Citation: DUAN Er-Yue, MA Jian-Gong, CHENG Peng. Advances in Gadolinium(Ⅲ) Chelates as MRI Contrast Agents[J]. University Chemistry, ;2016, 31(7): 1-13. doi: 10.3866/PKU.DXHX201512007 shu

Advances in Gadolinium(Ⅲ) Chelates as MRI Contrast Agents

College of Chemistry, Nankai Univeisity, Tianjin 300071, P. R. China

In this paper, the Gd(Ⅲ)-based contrast agents are reviewed from four aspects as followed:principles, conditions, research progresses and approaches for improving relaxivity. The research progresses in the fields of fluorescent and biological contrast agents are deeply introduced. Moreover, the activity of enzyme, pH and metal ions of biological contrast agents are discussed.
- Gd(Ⅲ)-based contrast agents,
- Principles,
- Relaxivity,
- Biological activity,
- Fluorescent sensor
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沈阳化工大学材料科学与工程学院沈阳 110142