Citation: YANG Chan, MAI Danti, PAN Zhemin, XUE Yun, WANG Yan, YAN Chao. Recent advances in the methods and applications used to analyze eicosanoids[J]. Chinese Journal of Chromatography, ;2016, 34(5): 449-455. doi: 10.3724/SP.J.1123.2016.01004 shu

Recent advances in the methods and applications used to analyze eicosanoids

  • Corresponding author: WANG Yan,  YAN Chao, 
  • Received Date: 4 January 2016

    Fund Project: 国家自然科学基金项目(21175092) (21175092)上海市科委科研计划项目(15142200200) (15142200200)上海市教育委员会科研创新项目(14YZ170) (14YZ170)中国博士后科学基金项目(2015M581628). (2015M581628)

  • Eicosanoids are a large family derived from polyunsaturated fatty acids, including prostaglandins, thromboxanes and leukotrienes. They are biologically active lipid mediators and are known to play an important role in numerous physiological and pathophysiological processes, such as inflammation. This complete enzymatic system produces hundreds of eicosanoids derived from arachidonic acids and related polyunsaturated fatty acids with very similar structures, chemistries and physical properties which makes the analysis of eicosanoids a challenging task, especially in biological samples. In this article, we review and discuss the methods and applications published over the last five years that have been used to analyze eicosanoids in biological samples, and emphasize the recent advances and the latest developments.
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