Home

Citation: WANG Hongrui, XIE Yuanyuan, LIANG Qionglin, WANG Yiming, HU Ping, LUO Guoan. Simultaneous determination of five Amadori compounds in tobacco by high performance liquid chromatography-mass spectrometry[J]. Chinese Journal of Chromatography, ;2013, 31(12): 1189-1193. doi: 10.3724/SP.J.1123.2013.06029 shu

Simultaneous determination of five Amadori compounds in tobacco by high performance liquid chromatography-mass spectrometry

WANG Hongrui ^1,2 ,
XIE Yuanyuan ^2,, ,
LIANG Qionglin ² ,
WANG Yiming ² ,
HU Ping ¹ ,
LUO Guoan ^1,2,,

1.
1. School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China;

Corresponding author: XIE Yuanyuan, LUO Guoan,
Received Date: 14 June 2013
Available Online: 8 September 2013
Fund Project:

A method of high performance liquid chromatography-triple quadrupole mass spectrometry (HPLC-QqQ MS) in multiple reaction monitoring (MRM) mode for simultaneous determination of five Amadori compounds in tobacco has been developed. The separation was performed on an XBridge^TM Amide column (250 mm×4.6 mm, 3.5 μm) by gradient elution using methanol and water as mobile phases. The linearity of this method was good with the correlation coefficients (r) of 0.9895-0.9989. The limits of detection (S/N=3) were from 3.51 μg/L to 14.86 μg/L, and the limits of quantitation (S/N=10) were from 10.18 μg/L to 44.58 μg/L. The recoveries varied from 92.6% to 123.6% with the relative standard deviations (RSDs) less than 9.4%. The established method is rapid, accurate, robust and convenient, and it could be applied to the measurement of the five Amadori compounds in tobacco and cigarettes.
- high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS),
- Maillard reaction,
- Amadori compounds,
- precursor aroma,
- tobacco
1. [1]
  [1] Cui T, Mao D B, Xu Z J. Guangxi Journal of Light Industry (崔韬, 毛多斌, 许志杰. 广西轻工业), 2010(12): 29
2. [2]
  [2] Wang J, Lu Y M, Liu B Z, et al. J Mass Spectrom, 2008, 43: 262
3. [3]
  [3] Eichner K, Reutter M, Wittmann R. The Maillard Reaction in Food ProcessIng, Human Nutrition and Physiology. Basel, Switzerland: Birkhauser Verlag, 1990: 63
4. [4]
  [4] Davidek T, Clety N, Devaud S, et al. J Agric Food Chem, 2003, 51: 7259
5. [5]
  [5] Davidek T, Kraehenbuehl K, Devaud S, et al. Anal Chem, 2005, 77: 140
6. [6]
  [6] Yang J Y, Mou D R, Mei Y, et al. Chinese Journal of Analysis Laboratory (杨金英, 牟定荣, 梅勇, 等. 分析试验室), 2010, 29(8): 97
7. [7]
  [7] Li W W, Dai Y H, Wu M J, et al. Journal of Instrumental Analysis (李苇苇, 戴云辉, 吴名剑, 等. 分析测试学报), 2009, 28(12): 1428
1. [1]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
2. [2]
  Hao Wu , Zhen Liu , Dachang Bai . ¹H NMR Spectrum of Amide Compounds. University Chemistry, 2024, 39(3): 231-238. doi: 10.3866/PKU.DXHX202309020
3. [3]
  Lili Jiang , Shaoyu Zheng , Xuejiao Liu , Xiaomin Xie . Copper-Catalyzed Oxidative Coupling Reactions for the Synthesis of Aryl Sulfones: A Fundamental and Exploratory Experiment for Undergraduate Teaching. University Chemistry, 2025, 40(7): 267-276. doi: 10.12461/PKU.DXHX202408004
4. [4]
  Yan Kong , Wei Wei , Lekai Xu , Chen Chen . Electrochemical Synthesis of Organonitrogen Compounds from N-integrated CO₂ Reduction Reaction. Acta Physico-Chimica Sinica, 2024, 40(8): 2307049-0. doi: 10.3866/PKU.WHXB202307049
5. [5]
  Qianlang Wang , Jijun Sun , Qian Chen , Quanqin Zhao , Baojuan Xi . The Appeal of Organophosphorus Compounds: Clearing Their Name. University Chemistry, 2025, 40(4): 299-306. doi: 10.12461/PKU.DXHX202405205
6. [6]
  Zhuoming Liang , Ming Chen , Zhiwen Zheng , Kai Chen . Multidimensional Studies on Ketone-Enol Tautomerism of 1,3-Diketones By ¹H NMR. University Chemistry, 2024, 39(7): 361-367. doi: 10.3866/PKU.DXHX202311029
7. [7]
  Chi Li , Jichao Wan , Qiyu Long , Hui Lv , Ying Xiong . N-Heterocyclic Carbene (NHC)-Catalyzed Amidation of Aldehydes with Nitroso Compounds. University Chemistry, 2024, 39(5): 388-395. doi: 10.3866/PKU.DXHX202312016
8. [8]
  Ying Xiong , Guangao Yu , Lin Wu , Qingwen Liu , Houjin Li , Shuanglian Cai , Zhanxiang Liu , Xingwen Sun , Yuan Zheng , Jie Han , Xin Du , Chengshan Yuan , Qihan Zhang , Jianrong Zhang , Shuyong Zhang . Basic Operations and Specification Suggestions for Determination of Physical Constants of Organic Compounds. University Chemistry, 2025, 40(5): 106-121. doi: 10.12461/PKU.DXHX202503079
9. [9]
  Yongjian Zhang , Fangling Gao , Hong Yan , Keyin Ye . Electrochemical Transformation of Organosulfur Compounds. University Chemistry, 2025, 40(5): 311-317. doi: 10.12461/PKU.DXHX202407035
10. [10]
  Nan Xiao , Fang Sun . 二芳基硫醚化合物的构建及应用. University Chemistry, 2025, 40(6): 360-363. doi: 10.12461/PKU.DXHX202407099
11. [11]
  Yerong Chen , Bingbin Yang , Xinglei He , Yuqi Lin , Keyin Ye . Enzyme-Directed Evolution Enables Bioconversion of Organosilicon Compounds. University Chemistry, 2025, 40(10): 121-129. doi: 10.12461/PKU.DXHX202411054
12. [12]
  Qiwen Chen , Baolei Wang . Research Progress on One-Electron σ-Bond of Organic Compounds. University Chemistry, 2025, 40(11): 191-198. doi: 10.12461/PKU.DXHX202412136
13. [13]
  Mingyang Men , Jinghua Wu , Gaozhan Liu , Jing Zhang , Nini Zhang , Xiayin Yao . Sulfide Solid Electrolyte Synthesized by Liquid Phase Approach and Application in All-Solid-State Lithium Batteries. Acta Physico-Chimica Sinica, 2025, 41(1): 100004-0. doi: 10.3866/PKU.WHXB202309019
14. [14]
  Geyang Song , Dong Xue , Gang Li . Recent Advances in Transition Metal-Catalyzed Synthesis of Anilines from Aryl Halides. University Chemistry, 2024, 39(2): 321-329. doi: 10.3866/PKU.DXHX202308030
15. [15]
  Jiaming Xu , Yu Xiang , Weisheng Lin , Zhiwei Miao . Research Progress in the Synthesis of Cyclic Organic Compounds Using Bimetallic Relay Catalytic Strategies. University Chemistry, 2024, 39(3): 239-257. doi: 10.3866/PKU.DXHX202309093
16. [16]
  Aidang Lu , Yunting Liu , Yanjun Jiang . Comprehensive Organic Chemistry Experiment: Synthesis and Characterization of Triazolopyrimidine Compounds. University Chemistry, 2024, 39(8): 241-246. doi: 10.3866/PKU.DXHX202401029
17. [17]
  Xilin Zhao , Xingyu Tu , Zongxuan Li , Rui Dong , Bo Jiang , Zhiwei Miao . Research Progress in Enantioselective Synthesis of Axial Chiral Compounds. University Chemistry, 2024, 39(11): 158-173. doi: 10.12461/PKU.DXHX202403106
18. [18]
  Hanxue LIU , Shijie LI , Meng REN , Xuling XUE , Hongke LIU . Design and antitumor properties of dehydroabietic acid functionalized cyclometalated iridium(Ⅲ) complex. Chinese Journal of Inorganic Chemistry, 2025, 41(8): 1483-1494. doi: 10.11862/CJIC.20250031
19. [19]
  Xiaodong Chen , Yumin Zhang . An Improved Simulated Annealing Algorithm for Predicting the Molecular Formulas of Organic Compounds. University Chemistry, 2025, 40(9): 19-24. doi: 10.12461/PKU.DXHX202408095
20. [20]
  Yijing GU , Huan PANG , Rongmei ZHU . Applications of nickel-based metal-organic framework compounds in supercapacitors. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 2029-2038. doi: 10.11862/CJIC.20250186

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(568)
HTML views(81)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return