Citation: JIN Yafeng, CHEN Na, LIU Runqiang, CHEN Jun, BAI Lianyang, ZHANG Yuping. Preparation and evaluation of molecularly imprinted polymer of olivetol for solid phase extraction[J]. Chinese Journal of Chromatography, ;2013, 31(6): 587-595. doi: 10.3724/SP.J.1123.2012.12014 shu

Preparation and evaluation of molecularly imprinted polymer of olivetol for solid phase extraction

JIN Yafeng ¹ ,
CHEN Na ¹ ,
LIU Runqiang ^1,2 ,
CHEN Jun ^1,2 ,
BAI Lianyang ² ,
ZHANG Yuping ^1,,

1.
1. Institute of Applied Chemistry, Henan Institute of Science and Technology, Xinxiang 453003, China;

Corresponding author: ZHANG Yuping,
Received Date: 5 December 2012
Available Online: 14 January 2013
Fund Project: Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry and the National Natural Science Foundation of China (30771436). (30771436)

Molecularly imprinted polymer (MIP) was synthesized by bulk polymerization, using olivetol as template molecule, methyl acrylic acid (MAA) as monomer, ethylene glycol dimethacrylate (EDMA) as crosslinker, toluene and dodecanol as solvents. The resulted MIP was characterized by the equilibrium binding experiments, scanning electron microscope (SEM) and Fourier transform infrared spectrometer (FTIR). The polymer was then applied to solid phase extraction (SPE) of olivetol from spiked wheat bran samples. From the equilibrium binding experiments, it was showed that MIP had a better recognizability for the template molecule. Scatchard analysis showed that MIP had specific adsorption to olivetol with two classes of binding sites. The high and low binding sites dissociation constants were 0.021 and 1.002 mmol/L. The corresponding maximum binding capacities were 18.74 and 135.9 μ mol/g, respectively. Under the optimum condition of SPE, the recoveries of olivetol on MIP cartridge were in the range of 97.8%-98.8%. The relative standard deviations (RSDs) were 2.8%-4.2%. The linearity range was between 0.1 and 100 mg/L. The limit of detection (S/N=3) was 0.062 mg/L. MIP cartridge showed stronger selectivity, higher recovery and purified the sample more drastically compared with non-imprinted polymer (NIP) cartridge and commercial poly(styrene/divinylbenzene) (PLS) cartridge.
- molecularly imprinted polymer (MIP),
- solid phase extraction,
- olivetol,
- bulk polymerization
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沈阳化工大学材料科学与工程学院沈阳 110142

Preparation and evaluation of molecularly imprinted polymer of olivetol for solid phase extraction

南开大学师唯/华北电力大学（保定）刘景维：二维配位聚合物中有序的亲锂冠醚位点用于无枝晶锂沉积

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通讯作者: 陈斌, bchen63@163.com