Citation:
LIAO Kechao, LU Fusui, LIU Cunping, XIA Hui. Preparation and Properties of Butylene Fipronilloaded Microcapsules[J]. Chinese Journal of Applied Chemistry,
;2014, 31(9): 1037-1043.
doi:
10.3724/SP.J.1095.2014.30582
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Butylene fipronil-loaded microcapsules were prepared by layer-by-layer self-assembly of oppositely charged chitosan and sodium alginate as shell materials. Sodium dodecyl benzene sulfonate was selected as the dispersant by flowing point method. The prepared microcapsules were characterized. The effect of drug loadings, entrapment efficiency, release profiles and photo degradation rate with the increase of layers was systematically studied. The results show that microcapsules with six to eight layers are the best with the entrapment efficiency up to 80%, the release time of 60 h and the photolysis rate down to 20%.
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Keywords:
- microcapsules,
- layer-by-layer,
- butylene fipronil,
- chitosan,
- sodium alginate
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