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Citation:
YAN Jiawen, MA Zhenmao. Preparation and Properties of Oleanolic Acid-Alkanolamines Complexes[J]. Chinese Journal of Applied Chemistry,
;2014, 31(7): 823-827.
doi:
10.3724/SP.J.1095.2014.30499
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Complexes of oleanolic acid(OA) and alkanolamines(EAs)[Ethanolamine(MEA),diethanolamine(DEA) or triethanolamine(TEA)]were prepared by an ultrasonic method.The complexes were characterized by DSC,XRD,IR and Raman spectroscopy.It was found that the complexes is formed through the intermolecular force between OA and EAs rather than chemical bonding.The solubility of OA-EAs complexes is much higher than that of OA.The present study supplies a novel concept for the design of an efficient delivery system of OA.
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Keywords:
- oleanic acid,
- alkanolamines,
- ultrasound method,
- solubility
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