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Citation: XIANG Dongshan, ZHAI Kun. Construction of Molecular Beacons and Their Research Progress of Application[J]. Chinese Journal of Applied Chemistry, ;2014, 31(1): 11-19. doi: 10.3724/SP.J.1095.2014.30116 shu

Construction of Molecular Beacons and Their Research Progress of Application

XIANG Dongshan ^a,b,, ,
ZHAI Kun ^b

1.
a Key Laboratory of Biologic Resources Protection and Utilization of Hubei Province;
2.
b School of Chemical and Environmental Engineering, Hubei University for Nationalities, Enshi 445000, China

Corresponding author: XIANG Dongshan,
Received Date: 8 March 2013
Available Online: 27 May 2013
Fund Project: 国家自然科学基金(21267009) (21267009)生物资源保护与利用湖北省重点实验室开放基金(PKLHB1110) (PKLHB1110)湖北省教育厅自然科学基金(D20131905) (D20131905)湖北民族学院博士科研启动基金(MY2012B016)资助项目 (MY2012B016)

Molecular beacon is an oligonucleotide probe of fluorescence.Molecular beacons are playing a very important role in molecular biology,genetics and molecular medicine because they have been shown to have very high selectivity,high sensitivity,and real-time detection capabilities.The structures and working mechanisms of a variety of novel molecular beacons have been outlined here.We briefly summarize the application of molecular beacon technology in the field of life sciences,and propose the prospect this technology.
- molecular beacons,
- construction,
- biochemical analysis,
- application
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