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Citation: LI Jingyun, WANG Yi, XU Jiali, LI Yuanfang. Detection of Cefazolin Based on the Plasmonic Resonance Absorption of Gold Nanoparticles[J]. Chinese Journal of Applied Chemistry, ;2012, 29(4): 455-461. doi: 10.3724/SP.J.1095.2012.00231 shu

Detection of Cefazolin Based on the Plasmonic Resonance Absorption of Gold Nanoparticles

1.
Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715

Corresponding author: LI Yuanfang,
Received Date: 30 May 2011
Available Online: 3 August 2011
Fund Project: 国家自然科学基金(NSFC,20775061) (NSFC,20775061)

The cefazolin can be detected according to the change of solution color resulting from the plasmonic resonance absorption of AuNPs.The absorbance ratio at 520/660 nm of AuNPs is proportional to the concentration of cefazolin in the range of 0.1~5.0 μmol/L with the detection limit of 14 nmol/L.This method could be extended to the determination of cefazolin sodium powder injection,the recovery of cefazolin was in the range of 97.4%~100.2% while the relative standard deviation was less than 6.1%.
- Gold nanoparticles,
- cefazolin,
- sodium chloride,
- plasma resonance absorption,
- colorimetric determination
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