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Citation: WANG Jianhua, ZHANG Chong. Recent Progress in Synthetic Methods of Small Molecule Antigen[J]. Chinese Journal of Applied Chemistry, ;2011, 28(4): 367-375. doi: 10.3724/SP.J.1095.2011.00364 shu

Recent Progress in Synthetic Methods of Small Molecule Antigen

WANG Jianhua ^, ,
ZHANG Chong

1.
College of Biomedical Engineering, Chongqing University, Chongqing 400044

Corresponding author: WANG Jianhua,
Received Date: 24 June 2010
Available Online: 10 September 2010
Fund Project: 国家科技支撑计划(2007BAD51B05) (2007BAD51B05)

With increasing applications of immune assay,the synthesis of artificial antigen with good stability and immunogenic is the key and premise to prepare the antibody and to establish the method for small molecule immune assay.The progress of synthesis and design method of hapten,carrier selection and the couple method of hapten with carrier are reviewed in this paper.In addition,some questions of the synthesis of small molecule artificial antigen were also discussed.
- artificial antigen,
- hapten,
- synthesis,
- immune assay
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