Citation:
ZHENG Yi, WANG Jun-Fang, ZHANG Ying-Peng, YANG Yun-Shang. Synthesis of Novel Pyridyl-pyrazole-5-carboxylic Acid Amide Compounds[J]. Chinese Journal of Applied Chemistry,
;2010, 27(9): 1105-1107.
doi:
10.3724/SP.J.1095.2010.90797
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Key intermediate pyridinyl-1H-pyrazole-5-carboxylic acid was synthesized from the reaction of 2,3-dichloropyridine with hydrazine,which was then treated with diethyl maleate,then esterified through halogenation,oxidation,hydrolysis.Carbonyl chloride was synthesized by dichloro sulfoxide,and pyridinyl-1H-pyrazole-5-carboxylic acid amide compounds were synthesized by carbonyl chloride reacting with corresponding ammonia.
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Keywords:
- pyridyl-pyrazolecarboxylic acid,
- amide,
- synthesis
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