Citation:
YANG Xin-Bin, ZHANG Jin-Sheng, CHEN Zhao-Hui, ZENG Ren-Quan. Synthesis and Characterization of A New Schiff Base Copper(Ⅱ) Complex from Tris(hydroxymethyl) aminomethane and 2-Pyridinecarboxaldehyde, and Its Interaction with DNA[J]. Chinese Journal of Applied Chemistry,
;2010, 27(8): 903-906.
doi:
10.3724/SP.J.1095.2010.90646
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A schiff base copper complex prepared through the condensation between tris (hydroxymethyl) aminomethane and 2-pyridinecarboxaldehyde was characterized by elemental analysis,molar conductance,IR and HRMS. The interaction of the complex with culf thymus (CT-DNA) was investigated by UV spectra, viscosity measurements and DNA thermal denaturation experiments. The experimental results show that the mode of the complex bound to DNA is intercalation.
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Keywords:
- copper complex,
- CT-DNA,
- inercalation
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