Citation: CHENG Shi-Qi, YANG Jin, QIN Shang-Ying, HUANG Li, SHI Rui, WANG Yi-Lin. Molecularly Imprinted Glucose Electrochemical Sensor Sensitized by Carbon Quantum Dots[J]. Chinese Journal of Analytical Chemistry, ;2023, 51(4): 549-558. doi: 10.19756/j.issn.0253-3820.221338 shu

Molecularly Imprinted Glucose Electrochemical Sensor Sensitized by Carbon Quantum Dots

Guangxi Key Laboratory of Electrochemical Energy Materials, School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China

Corresponding author: WANG Yi-Lin, theanalyst@163.com
Received Date: 9 July 2022
Revised Date: 16 October 2022

Fund Project: Supported by the Innovation Project of Guangxi Graduate Education (No. YCSW2021050) and the Opening Project of Guangxi Key Laboratory of Electrochemical Energy Materials (No. KF2020012).

An enzyme-free molecularly imprinted electrochemical sensor was constructed for highly sensitive determination of glucose. The molecular imprinting polymer was electro-deposited on the surface of carbon quantum dots and chitosan modified glassy carbon electrode using 3-aminobenzeneboronic acid as functional monomer and glucose as template molecule. The electrochemical and analytical characteristics of the sensor were investigated by cyclic voltammetry, electrochemical impedance spectroscopy and differential pulse voltammetry. Under the optimal conditions, variation of the peak current of the sensor showed good linear correlation with the glucose concentration in the range of 0.1-1.0 μmol/L and 1.0-300 μmol/L, respectively. The linear regression equations were ΔI_p (μA)=3.792 + 23.41C (R²=0.9968) and ΔI_p (μA)=28.18 +0.1316C (R²=0.9914), respectively, with a detection limit of 0.034 μmol/L (3σ/k). The method exhibited potential application in detection of glucose in body fluids with recoveries of 95.1%-106.8%.
- Carbon quantum dots,
- Molecular imprinting polymer,
- Electrochemical sensor,
- Glucos
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