Citation: TIAN Wen-Shuai, CAO Hou-Yong, GAO Jie, ZHANG Yu, CAI Wu-Qi, WANG Fan, HUI Yu, WANG Xing-An, ZHANG Xu-Xin, SUN Jing, LI Yan-Zhao. Research Progress of Wearable Flexible Sensors Based on Polydimethylsiloxane[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(11): 1712-1722. doi: 10.19756/j.issn.0253-3820.221274 shu

Research Progress of Wearable Flexible Sensors Based on Polydimethylsiloxane

TIAN Wen-Shuai ¹ ,
CAO Hou-Yong ¹ ,
GAO Jie ¹ ,
ZHANG Yu ¹ ,
CAI Wu-Qi ¹ ,
WANG Fan ^1,1 ,
HUI Yu ^1,2 ,
WANG Xing-An ³ ,
ZHANG Xu-Xin ^1,4 ,
SUN Jing ^3,, ,
LI Yan-Zhao ^,

1.
College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China;
2.
Dalian Chivy Biotechnology Co., Ltd., Dalian 116023, China;
3.
Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China;
4.
Dalian Key Laboratory of Oligosaccharide Recombination and Recombinant Protein Modification, Dalian 116622, China

Corresponding author: SUN Jing, LI Yan-Zhao,
Received Date: 31 May 2022
Revised Date: 5 July 2022

Fund Project: Supported by the Liaoning Province-Shenyang National Laboratory for Materials Science Joint Research and Development Fund (No.2019010274-JH3/301), the Natural Science Foundation of Liaoning Province (No.2021JH6/10500143), the Innovation and Entrepreneurship Team Fund of Dalian University, the Natural Science Foundation of Liaoning Province, China (No.2020-KF-14-05) and the State Key Laboratory of Light Alloy Casting Technology for High-end Equipment (No.LACT-006).

A wearable flexible sensor is a device that is tightly attached to the skin or tissue of human to collect physiological parameters of the body for data analysis and reference in real time, which has important applications in the fields of medical care, diagnosis and treatment, etc. With the advantages such as stable chemical properties, strong thermal stability, good transparency and biocompatibility, polydimethylsiloxane (PDMS) has been proved to be the best choice for wearable flexible sensors substrates,which can achieve different functions through surface modification and overall characteristic customization. In this paper, the research progress of wearable flexible sensors based on PDMS in recent years is reviewed, as well as the working principles of the sensors and performance comparisons of conductive modified materials. The performance parameters, advantages and disadvantages of different conductive modified materials are exhibited and compared due to their significance in the sensors. This review also introduces different sensors from the application aspect, such as photosensors, temperature sensors, strain sensors, pressure sensors and biochemical sensors. Finally, the challenges and development directions of wearable sensors are prospected.
- Wearable,
- Flexible sensors,
- Polydimethylsiloxane,
- Health monitoring,
- Review
1. [1]
2. [2]
3. [3]
  ROSSI E, SALAHSHOOR Z, HO K V, LIN C H, ERREA M I, FIDALGO M M. Microchim. Acta, 2021, 188(3):70.
4. [4]
  KUZUBASOGLU B A, BAHADIR S K. Sens. Actuators, A, 2020, 315:112282.
5. [5]
  ZHANG J, ZHANG Y, LI Y, WANG P. Polym. Rev., 2022, 62(1):65-94.
6. [6]
  HAN T, NAG A, AFSARIMANESH N, MUKHOPADHYAY S C, KUNDU S, XU Y Z. Sensors, 2019, 19(6):1462.
7. [7]
  KATARIA D, SANCHEZ G, NAIDU J P, SRINIVASAN M A. IETE J. Res., 2021, 67:646-653.
8. [8]
  KWAK Y H, KIM W, PARK K B, KIM K, SEO S. Biosens. Bioelectron., 2017, 94:250-255.
9. [9]
  WANG X F, YU J H, CUI Y X, LI W. Sens. Actuators, A, 2021, 330:112838.
10. [10]
  PATEL S, PARK H, BONATO P, CHAN L, RODGERS M. J. Neuroeng. Rehabil., 2012, 9:21.
11. [11]
  QI D P, ZHANG K Y, TIAN G W, JIANG B, HUANG Y D. Adv.Mater., 2021, 33(6):2003155.
12. [12]
  SHER M, ZHUANG R, DEMIRCI U, ASGHAR W. Expert. Rev. Mol. Diagn., 2017, 17(4):351-366.
13. [13]
  YANG Y B, YANG X D, TAN Y N, YUAN Q. Nano Res., 2017, 10(5):1560-1583.
14. [14]
  CHEN J, ZHENG J H, GAO Q W, ZHANG J J, ZHANG J Y, OMISOREO M, WANG L, LI H. Appl. Sci., 2018, 8(3):345.
15. [15]
  XU C, MIAO L M, WANG H B, REN Z Y, GUO H, ZHANG H X. IEEE Trans. Nanotechnol., 2021, 20:137-142.
16. [16]
  CHEN S W, QI J M, FAN S C, QIAO Z, YEO J C, LIM C T. Adv. Healthcare Mater., 2021, 10(17):2100116.
17. [17]
  NGUYEN T D, LEE J S. Sensors, 2022, 22(1):50.
18. [18]
  XIANG L, ZENG X W, XIA F, JIN W L, LIU Y D, HU Y F. ACS Nano, 2020, 14(6):6449-6469.
19. [19]
  JEONG Y R, LEE G, PARK H, HA J S. Acc. Chem. Res., 2019, 52(1):91-99.
20. [20]
  VAN DEN B J, DE KOK M, KOETSE M, CAUWE M, VERPLANCKE R, BOSSUYT F, JABLONSKI M, VANFLETEREN J. Solid-State. Electron., 2015, 113:116-120.
21. [21]
  SAVAGATRUP S, PRINTZ A D, O'CONNOR T F, ZARETSKI A V, LIPOMI D J. Chem. Mater., 2014, 26(10):3028-3041.
22. [22]
  SCHROEDER V, SAVAGATRUP S, HE M, LING S B, SWAGER T M. Chem. Rev., 2019, 119(1):599-663.
23. [23]
  JUSTINO C I L, COMES A R, FREITAS A C, DUARTE A C, ROCHA-SANTOS T A P. TrAC, Trends Anal. Chem., 2017, 91:53-66.
24. [24]
  BIALAS K, MOSCHOU D, MARKEN F, ESTRELA P. Microchim. Acta, 2022, 189(4):172.
25. [25]
  PAVEL I A, LAKARD S, LAKARD B. Chemosensors, 2022, 10(3):97.
26. [26]
  CHEN X L, ZENG Q, SHAO J Y, LI S, LI X M, TIAN H M, LIU G F, NIE B B, LUO Y S. ACS Appl. Mater. Interfaces, 2021, 13(29):34637-34647.
27. [27]
  WANG D, SHENG B, PENG L N, HUANG Y S, NI Z J. Polymers, 2019, 11(9):1433.
28. [28]
29. [29]
  YANG T, DENG W L, CHU X, WANG X, HU Y T, FAN X, SONG J, GAO Y Y, ZHANG B B, TIAN G, XIONG D, ZHONG S, TANG L H, HU Y H, YANG W Q. ACS Nano, 2021, 15(7):11555-11563.
30. [30]
  ZHANG K M, SUN J W, SONG J Y, GAO C H, WANG Z, SONG C X, WU Y M, LIU Y T. ACS Appl. Mater. Interfaces, 2020, 12(40):45306-45314.
31. [31]
  FERRIER D C, HONEYCHURCH K C. Biosensors, 2021, 11(12):486.
32. [32]
  MICHEL T R, CAPASSO M J, CAVUSOGLU M E, DECKER J, ZEPPILLI D, ZHU C, BAKRANIA S, KADLOWEC J A, XUE W. Microsyst. Technol., 2020, 26(4):1101-1112.
33. [33]
  LIU K, YANG C, SONG L H, WANG Y, WEI Q, ALAMUSI, DENG Q B, HU N. Compos. Sci. Technol., 2022, 218:109148.
34. [34]
  CHEN J W, ZHU Y T, JIANG W. Compos. Sci. Technol., 2020, 186:107938.
35. [35]
  SINGH E, MEYYAPPAN M, NALWA H S. ACS Appl. Mater. Interfaces, 2017, 9(40):34544-34586.
36. [36]
  JIRICKOVA A, JANKOVSKY O, SOFER Z, SEDMIDUBSKY D. Materials, 2022, 15(3):920.
37. [37]
  TIAN H, SHU Y, CUI Y L, MI W T, YANG Y, XIE D, REN T L. Nanoscale, 2014, 6(2):699-705.
38. [38]
  GUAN H, MENG J W, CHENG Z Y, WANG X Q. ACS Appl. Mater. Interfaces, 2020, 12(41):46357-46365.
39. [39]
  WANG H H, CEN Y M, ZENG X Q. ACS Appl. Mater. Interfaces, 2021, 13(24):28538-28545.
40. [40]
  MAO Y Y, JI B, CHEN G, HAO C X, ZHOU B P, TIAN Y Q. ACS Appl. Nano Mater., 2019, 2(5):3196-3205.
41. [41]
  MAZUMDER V, CHI M F, MORE K L, SUN S H. Angew. Chem., Int. Ed., 2010, 49(49):9368-9372.
42. [42]
  ZHANG X M, YANG X L, WANG B. J. Mater. Sci-Mater. El., 2022, 33(10):8104-8113.
43. [43]
  BAE C W, TOI P T, KIM B Y, LEE W I, LEE H B, HANIF A, LEE E H, LEE N E. ACS Appl. Mater. Interfaces, 2019, 11(16):14567-14575.
44. [44]
  LUAN R F, AN H, CHEN C, XUE Y, GUO A L, CHU L, AHMAD W, LI X A. Z. Anorg. Allg. Chem., 2021, 647(9):1031-1037.
45. [45]
  MEI J, BAO Z. Chem. Mater., 2014, 26(1):604-615.
46. [46]
  WU H C, HONG C W, CHEN W C. Polym. Chem., 2016, 7(26):4378-4392.
47. [47]
  TAN Z T, LI H W, HUANG Y N, GONG X, QI J N, LI J, CHEN X S, JI D Y, LV W B, LI L Q, HU W P. Composites, 2021, 143:106299.
48. [48]
  QI D P, LIU Z Y, LIU Y, JIANG Y, LEOW W R, PAL M, PAN S W, YANG H, WANG Y, ZHANG X Q, YU J C, LI B, YU Z, WANG W, CHEN X D. Adv. Mater., 2017, 29(40):1702800.
49. [49]
  ZHANG Y, HU Y, ZHU P, HAN F, ZHU Y, SUN R, WONG C P. ACS Appl. Mater. Interfaces, 2017, 9(41):35968-35976.
50. [50]
  LEE M S, LEE K, KIM S Y, LEE H, PARK J, CHOI K H, KIM H K, KIM D G, LEE D Y, NAM S, PARK J U. Nano Lett., 2013, 13(6):2814-2821.
51. [51]
  SEGEV-BAR M, HAICK H. ACS Nano, 2013, 7(10):8366-8378.
52. [52]
  PUNEETHA P, MALLEM S P R, LEE Y W, SHIM J. ACS Appl. Mater. Interfaces, 2020, 12(32):36660-36669.
53. [53]
  WANG W, XIANG C X, ZHU Q, ZHONG W B, LI M F, YAN K L, WANG D. ACS Appl. Mater. Interfaces, 2018, 10(32):27215-27223.
54. [54]
  YU Q Y, ZHANG P, CHEN Y C. Micromachines, 2021, 12(10):1219.
55. [55]
  SONG Y H, DONG H, LIU W X, FU X, FU Z, LI P L, CHEN L, AHMAD Z, LIU J, CHEN X, CHANG M W. ACS. Appl. Polym. Mater., 2022, 4(2):868-878
56. [56]
  ZHENG Q B, LEE J H, SHEN X, CHEN X D, KIM J K. Mater. Today, 2020, 36:158-179.
57. [57]
  KIM T Y, SUH W, JEONG U. Mat. Sci. Eng. R., 2021, 146:100640.
58. [58]
  LI Z W, CHENG L, SONG Q K. IEEE. Sens. J., 2021, 21(4):4365-4376.
59. [59]
  HU Y F, HUANG T Q, ZHANG H J, LIN H J, ZHANG Y, KE L W, CAO W, HU K, DING Y, WANG X Y, RUI K, ZHU J X, HUANG W. ACS Appl. Mater. Interfaces, 2021, 13(20):23905-23914.
60. [60]
  LEE M E, ARMANI A M. ACS Sens., 2016, 1(10):1251-1255.
61. [61]
  RYU D, MONGARE A. Materials, 2018, 11(10):1970.
62. [62]
  HERBERT R, LIM H R, YEO W H. ACS Appl. Mater. Interfaces, 2020, 12(22):25020-25030.
63. [63]
  LI T Y, LI J H, ZHONG A, HAN F, SUN R, WONG C P, NIU F F, ZHANG G P, JIN Y F. Sens. Actuators, A, 2020, 306:111959.
64. [64]
  HAN M, LEE J, KIM J K, AN H K, KANG S W, JUNG D. Sens. Actuators, A, 2020, 305:111941.
65. [65]
  WANG F F, TAN Y H, PENG H Y, MENG F C, YAO X G. Mater. Lett., 2021, 303:130512.
66. [66]
  LI W, JIN X, HAN X, LI Y R, WANG W Y, LIN T, ZHU Z T. ACS Appl. Mater. Interfaces, 2021, 13(16):19211-19220.
67. [67]
  PEGAN J D, ZHANG J, CHU M, NGUYEN T, PARK S J, PAUL A, KIM J, BACHMAN M, KHINE M. Nanoscale, 2016, 8(39):17295-17303.
68. [68]
  LIU R P, HE L, CAO M J, SUN Z C, ZHU R Q, LI Y. Front. Chem., 2021, 9:539678.
69. [69]
  YANG J, WEI D P, TANG L L, SONG X F, LUO W, CHU J, GAO T P, SHI H F, DU C L. RSC Adv., 2015, 5(32):25609-25615.
70. [70]
  LI Y C, ZHENG C R, LIU S, HUANG L, FANG T S, LI J X Z, XU F, LI F. ACS Appl. Mater. Interfaces, 2020, 12(21):23764-23773.
71. [71]
  GAO Y J, YU L T, YEO J C, LIM C T. Adv. Mater., 2020, 32(15):1902133.
72. [72]
  SHEN G Z. Prog. Nat. Sci.-Mater., 2021, 31(6):872-882.
73. [73]
  SHU Y, SHANG Z J, SU T, ZHANG S H, LU Q, XU Q, HU X Y. Analyst, 2022, 147(7):1440-1448.
74. [74]
  HUI X, XUAN X, KIM J, PARK J Y. Electrochim. Acta, 2019, 328:135066.
75. [75]
  LIU Q, SHI W S, TIAN L, SU M J, JIANG M Y, LI J, GU H Y, YU C M. Anal. Chim. Acta, 2021, 1184:339010.
76. [76]
  ZHAO T M, ZHENG C W, HE H X, GUAN H Y, ZHONG T Y, XING L L, XUE X Y. Smart Mater. Struct., 2019, 28(8):085015.
77. [77]
  ZHAO Z T, HUANG Y Y, LI Q G, MEI H J, ZHU F L, GONG W P. Appl. Surf. Sci., 2021, 565:150553.
78. [78]
  YANG A N, YAN F. ACS Appl. Electron. Mater., 2021, 3(1):53-67.
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