Citation: YU Qiong-Lin, LIANG Ping, JIAN Wei, QIAO Ting-Yi, DONG Nan. Column-free Matrix Solid Phase Dispersion Extraction Based on Cucurbit[7]uril Coupled with High Performance Liquid Chromatography for Determination of Camptothecin Content in Camptotheca acuminate Decne[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(8): 1217-1223. doi: 10.19756/j.issn.0253-3820.221066 shu

Column-free Matrix Solid Phase Dispersion Extraction Based on Cucurbit[7]uril Coupled with High Performance Liquid Chromatography for Determination of Camptothecin Content in Camptotheca acuminate Decne

YU Qiong-Lin ¹ ,
LIANG Ping ¹ ,
JIAN Wei ¹ ,
QIAO Ting-Yi ¹ ,
DONG Nan ^1,2,,

1.
School of Chemistry and Chemical Engineering, Guizhou University, Guiyang 550025, China;
2.
Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guiyang 550025, China

Corresponding author: DONG Nan, ndong@gzu.edu.cn
Received Date: 9 February 2022
Revised Date: 26 May 2022

Fund Project: Supported by the Guizhou Science and Technology Foundation (No.ZK[2021] General 054) and the National Natural Science Foundation of China (No.22164006).

A simple, rapid and environmentally friendly method named column-free matrix solid-phase dispersion (FMSPD) was developed for extraction of camptothecin from the fruits of Camptotheca acuminate Decne. Cucurbit[7]uril (Q[7]) was used as the sorbent of FMSPD to selectively extract camptothecin, which was transferred into an aqueous solution and was directly detected using high performance liquid chromatography-ultraviolet detector (HPLC-UV) based on the recognition interaction of Q[7] toward the compound. The factors that influenced the extraction efficiency were investigated, including the amount of Q[7], grinding time, volume of added water, and pH value of the solution. Under the optimal experimental conditions, the dynamic linear range of the developed FMSPD-HPLC-UC method was 1.0-100 μg/mL, the limit of detection was 0.15 μg/mL, and the intra- and inter-day precisions were 4.5% and 5.2%, respectively. The mean recoveries (n=3) at three spiked concentration levels were from 97.1% to 119.3%. The developed method was applied to analyze four kinds of fruits of Camptotheca acuminate Decne.F- and t-tests showed that the results had no significant difference when comparing the traditional ultrasound-assisted extraction method to the novel FMSPD extraction method. However the method developed here was simpler, faster and did not use organic solvents.
- Cucurbit[7]uril,
- Matrix solid phase dispersion,
- Camptothecin,
- Fruits of Camptotheca acuminate Decne
1. [1]
2. [2]
3. [3]
4. [4]
  HOFF R B, PIZZOLATO T M. TrAC, Trend. Anal. Chem., 2018, 109:83-96.
5. [5]
  RAMOS L. TrAC, Trend. Anal. Chem., 2019, 118:751-758.
6. [6]
  PENG L Q, LI Q, CHANG Y X, AN M, YANG R, TAN Z J, HAO J, CAO J, XU J J, HU S S. J. Chromatogr. A, 2016, 1456:68-76.
7. [7]
  HU Y H, WANG Q Y, YE L H, YANG J, DONG X, ZHENG H, ZHOU J. Ind. Crop. Prod, 2019, 141:111752.
8. [8]
  LEON-GONZALEZ M E, ROSALES-CONRADA N. J. Chromatogr. A, 2017, 1514:88-94.
9. [9]
  LOZOWICKA B, ILYASOVA G, KACZYNSKI P, JANKOWSKA M, RUTKOWSKA E, HRYNKO I, MOJSAK P, SZABUNKO J. Talanta, 2016, 151:51-61.
10. [10]
  CAPRIOTTI A L, CAVALIERE C, FOGLIA P, SAMPERI R, STAMPACHIACCHIERE S, VENTURA S, LAGANA A. TrAC, Trend. Anal. Chem., 2015, 71:186-193.
11. [11]
  RAN J F, ZHANG L X, YAO J M, WANG S S, LIANG P, DONG N. Food Chem., 2021, 350:129236.
12. [12]
  GHOLAMI H, ARABI M, GHAEDI M, OSTOVAN A, BAGHERI A R. J. Chromatogr. A, 2019, 1594:13-22.
13. [13]
  LEE J W, SAMAL S, SELVAPALAM N, KIM H J, KIM K. Acc. Chem. Res., 2003, 36(8):621-630.
14. [14]
  ONG W, KAIFER A E. Organometallics, 2003, 22(21):4181-4183.
15. [15]
16. [16]
  LIANG F, YANG W S. Curr. Nanosci., 2019, 15:326-327.
17. [17]
  ELBASHIR A A, ABOUL-ENEIN H Y. Crit. Rev. Anal. Chem., 2015, 45:52-61.
18. [18]
  MA D, HETTIARACHCHI G, NGUYEN D, ZHANG B, WITTENBERG J B, ZAVALIJ P Y, BRIKEN V, ISAACS L. Nat. Chem., 2012, 4(6):503-510.
19. [19]
  MACARTNEY D H. Isr. J. Chem., 2011, 51(5-6):600-615.
20. [20]
  CONG H, TAO Z, XUE S F, ZHU Q J. Curr. Org. Chem., 2011, 15(1):86-95.
21. [21]
  DONG N, XUE S F, ZHU Q J, TAO Z, ZHAO Y, ZHANG B, PENG Z B. Supramol. Chem., 2008, 20(7):659-665.
22. [22]
  DONG N, DONG M Y, ZHAO A T, ZHU Q J, TAO Z, ZHAO Y. Sci. China:Chem., 2010, 53(11):2304-2310.
23. [23]
24. [24]
  GEMPERLINE P J. Taylor&Francis Group, New York, 2006:18-25.
1. [1]
  Zhilian Liu , Wengui Wang , Hongxiao Yang , Yu Cui , Shoufeng Wang . Ideological and Political Education Design for the Synthesis of Irinotecan Drug Intermediate 7-Ethyl Camptothecin. University Chemistry, 2024, 39(2): 89-93. doi: 10.3866/PKU.DXHX202306012
2. [2]
  Yanhui Zhong , Ran Wang , Zian Lin . Analysis of Halogenated Quinone Compounds in Environmental Water by Dispersive Solid-Phase Extraction with Liquid Chromatography-Triple Quadrupole Mass Spectrometry. University Chemistry, 2024, 39(11): 296-303. doi: 10.12461/PKU.DXHX202402017
3. [3]
  Conghao Shi , Ranran Wang , Juli Jiang , Leyong Wang . The Illustration on Stereoisomers of Macrocycles Containing Multiple Chiral Centers via Tröger Base-based Macrocycles. University Chemistry, 2024, 39(7): 394-397. doi: 10.3866/PKU.DXHX202311034
4. [4]
  Jiaxin Su , Jiaqi Zhang , Shuming Chai , Yankun Wang , Sibo Wang , Yuanxing Fang . Optimizing Poly(heptazine imide) Photoanodes Using Binary Molten Salt Synthesis for Water Oxidation Reaction. Acta Physico-Chimica Sinica, 2024, 40(12): 2408012-. doi: 10.3866/PKU.WHXB202408012
5. [5]
  Chongjing Liu , Yujian Xia , Pengjun Zhang , Shiqiang Wei , Dengfeng Cao , Beibei Sheng , Yongheng Chu , Shuangming Chen , Li Song , Xiaosong Liu . Understanding Solid-Gas and Solid-Liquid Interfaces through Near Ambient Pressure X-Ray Photoelectron Spectroscopy. Acta Physico-Chimica Sinica, 2025, 41(2): 100013-. doi: 10.3866/PKU.WHXB202309036
6. [6]
  Chunai Dai , Yongsheng Han , Luting Yan , Zhen Li , Yingze Cao . Ideological and Political Design of Solid-liquid Contact Angle Measurement Experiment. University Chemistry, 2024, 39(2): 28-33. doi: 10.3866/PKU.DXHX202306065
7. [7]
  Fang Niu , Rong Li , Qiaolan Zhang . Analysis of Gas-Solid Adsorption Behavior in Resistive Gas Sensing Process. University Chemistry, 2024, 39(8): 142-148. doi: 10.3866/PKU.DXHX202311102
8. [8]
  Limei CHEN , Mengfei ZHAO , Lin CHEN , Ding LI , Wei LI , Weiye HAN , Hongbin WANG . Preparation and performance of paraffin/alkali modified diatomite/expanded graphite composite phase change thermal storage material. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 533-543. doi: 10.11862/CJIC.20230312
9. [9]
  Jing WU , Puzhen HUI , Huilin ZHENG , Pingchuan YUAN , Chunfei WANG , Hui WANG , Xiaoxia GU . Synthesis, crystal structures, and antitumor activities of transition metal complexes incorporating a naphthol-aldehyde Schiff base ligand. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2422-2428. doi: 10.11862/CJIC.20240278
10. [10]
  Yanan Liu , Yufei He , Dianqing Li . Preparation of Highly Dispersed LDHs-based Catalysts and Testing of Nitro Compound Reduction Performance: A Comprehensive Chemical Experiment for Research Transformation. University Chemistry, 2024, 39(8): 306-313. doi: 10.3866/PKU.DXHX202401081
11. [11]
  Xin MA , Ya SUN , Na SUN , Qian KANG , Jiajia ZHANG , Ruitao ZHU , Xiaoli GAO . A Tb₂ complex based on polydentate Schiff base: Crystal structure, fluorescence properties, and biological activity. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1347-1356. doi: 10.11862/CJIC.20230357
12. [12]
  Jinlong YAN , Weina WU , Yuan WANG . A simple Schiff base probe for the fluorescent turn-on detection of hypochlorite and its biological imaging application. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1653-1660. doi: 10.11862/CJIC.20240154
13. [13]
  Yanyang Li , Zongpei Zhang , Kai Li , Shuangquan Zang . Ideological and Political Design for the Comprehensive Experiment of the Synthesis and Aggregation-Induced Emission (AIE) Performance Study of Salicylaldehyde Schiff-Base. University Chemistry, 2024, 39(2): 105-109. doi: 10.3866/PKU.DXHX202307020
14. [14]
  Yurong Tang , Yunren Shi , Yi Xu , Bo Qin , Yanqin Xu , Yunfei Cai . Innovative Experiment and Course Transformation Practice of Visible-Light-Mediated Photocatalytic Synthesis of Isoquinolinone. University Chemistry, 2024, 39(5): 296-306. doi: 10.3866/PKU.DXHX202311087
15. [15]
  Zian Lin , Yingxue Jin . Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) for Disease Marker Screening and Identification: A Comprehensive Experiment Teaching Reform in Instrumental Analysis. University Chemistry, 2024, 39(11): 327-334. doi: 10.12461/PKU.DXHX202403066
16. [16]
  Yang YANG , Pengcheng LI , Zhan SHU , Nengrong TU , Zonghua WANG . Plasmon-enhanced upconversion luminescence and application of molecular detection. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 877-884. doi: 10.11862/CJIC.20230440
17. [17]
  Lijuan Wang , Yuping Ning , Jian Li , Sha Luo , Xiongfei Luo , Ruiwen Wang . Enhancing the Advanced Nature of Natural Product Chemistry Laboratory Courses with New Research Findings: A Case Study of the Application of Berberine Hydrochloride in Photodynamic Antimicrobial Films. University Chemistry, 2024, 39(11): 241-250. doi: 10.12461/PKU.DXHX202403017
18. [18]
  Zhanhui Yang , Jiaxi Xu . (m+n+…) or [m+n+…]cycloaddition?. University Chemistry, 2025, 40(3): 387-389. doi: 10.12461/PKU.DXHX202406032
19. [19]
  Jianbao Mei , Bei Li , Shu Zhang , Dongdong Xiao , Pu Hu , Geng Zhang . Enhanced Performance of Ternary NASICON-Type Na_3.5-xMn_0.5V_1.5-xZr_x(PO₄)₃/C Cathodes for Sodium-Ion Batteries. Acta Physico-Chimica Sinica, 2024, 40(12): 2407023-. doi: 10.3866/PKU.WHXB202407023
20. [20]
  Zhangshu Wang , Xin Zhang , Jixin Han , Xuebing Fang , Xiufeng Zhao , Zeyu Gu , Jinjun Deng . Exploration and Design of Experimental Teaching on Ultrasonic-Enhanced Synergistic Treatment of Ternary Composite Flooding Produced Water. University Chemistry, 2024, 39(5): 116-124. doi: 10.3866/PKU.DXHX202310056

Get Citation

PDF

XML

Metrics

PDF Downloads(9)
Abstract views(430)
HTML views(51)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142