Citation: CHEN Ye-Quan, QUAN Shuai, DU Fang-Xin, LOU Bao-Hua, LI Jian-Ping, XU Guo-Bao. Recent Advances in Chemiluminescence and Electrochemiluminescence Assays of Acute Myocardial Infarction Biomarkers[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(6): 849-857. doi: 10.19756/j.issn.0253-3820.211223 shu

Recent Advances in Chemiluminescence and Electrochemiluminescence Assays of Acute Myocardial Infarction Biomarkers

CHEN Ye-Quan ^1,2,3 ,
QUAN Shuai ^1,2,3 ,
DU Fang-Xin ^2,3 ,
LOU Bao-Hua ^2,3 ,
LI Jian-Ping ^1,, ,
XU Guo-Bao ^1,2,3,,

1.
College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China;
2.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China;
3.
University of Science and Technology of China, Hefei 230022, China

Corresponding author: LI Jian-Ping, XU Guo-Bao,
Received Date: 18 March 2021
Revised Date: 9 April 2021

Fund Project: Supported by the National Key Research and Development Program of China (No.2016YFA0201300), the National Natural Science Foundation of China (No.21874126) and the Department of Science and Technology of Jilin Province, China(No.20200703024ZP).

Chemiluminescence (CL) and electrochemiluminescence (ECL) assays are widely utilized in clinical diagnosis, drug analysis, food testing, environmental monitoring and other fields because of their superiorities of high sensitivity, rapid analysis and facile operation. In this review, the recent advances of CL and ECL assays of acute myocardial infarction biomarkers were emphatically summarized. The diagnostic value of cardiac troponin, myoglobin, heart type fatty acid-binding protein, creatine kinase MB, copeptin and myocardial specific microRNAs as biomarkers were compared. The fabrication and application advantages of these Cl and ECL biosensors were discussed. Furthermore, the further research orientations were also prospected.
- Acute myocardial infarction,
- Biomarkers,
- Chemiluminescence,
- Electrochemiluminescence,
- Review
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