Citation: CAI Qi-Yong, LEI Yang, LI Zhao-Hui. Application Advances in Single Molecule Array Technology for Diagnosis of Disease[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(7): 1154-1165. doi: 10.19756/j.issn.0253-3820.211087 shu

Application Advances in Single Molecule Array Technology for Diagnosis of Disease

College of Chemistry, Zhengzhou University, Zhengzhou 450001, China

Corresponding author: LI Zhao-Hui, zhaohui.li@zzu.edu.cn
Received Date: 30 January 2021
Revised Date: 25 April 2021

Fund Project: Supported by the Zhengzhou Major Project for Collaborative Innovation (No.18XTZX12002).

Single molecule array technology (Simoa) is a digital enzyme-linked immunosorbent assay (ELISA) that performs single-molecule enzymatic reactions in microwell with a volume of femtoliters and enables fluorescence imaging. Simoa has many advantages such as rapidity, high sensitivity and wide detection range, which has shown great application potential in the fields of bioanalysis, disease diagnosis and prognosis evaluation. On the basis of summarizing the principles and key technologies of Simoa, in this article, the application progress of Simoa in the fields of neurodegenerative diseases, tumors, infectious diseases, etc., were mainly reviewed, and application prospects of Simoa were anticipated.
- Single molecule array,
- Fluorescence imaging,
- Digital enzyme-linked immunosorbent assay,
- Diagnosis,
- Review
1. [1]
  WALT D R. Chem. Soc. Rev., 2010, 39(1): 38-50.
2. [2]
  GORRIS H H, WALT D R. Angew. Chem., Int. Ed., 2010, 49(23): 3880-3895.
3. [3]
  WU C, MALEY A M, WALT D R. Crit. Rev. Clin. Lab. Sci., 2019: 1-21.
4. [4]
  COHEN L, WALT D R. Annu. Rev. Anal. Chem., 2017, 10(1): 345-363.
5. [5]
  RISSIN D M, WALT D R. Nano Lett., 2006, 6(3): 520-523.
6. [6]
  ZHANG H, NIE S, ETSON C M, WANG R M, WALT D R. Lab Chip, 2012, 12(12): 2229-2239.
7. [7]
  RISSIN D M, KAN C W, CAMPBELL T G, HOWES S C, FOURNIER D R, SONG L, PIECH T, PATEL P P,CHANG L, RIVNAK A J, FERRELL E P, RANDALL J D, PROVUNCHER G K, WALT D R, DUFFY D C. Nat. Biotechnol., 2010, 28(6): 595-599.
8. [8]
  KAN C W, RIVNAK A J, CAMPBELL T G, PIECH T, RISSIN D M, MOSL M, PETERCA A, NIEDERBERGER H P, MINNEHAN K A, PATEL P P, FERRELL E P, MEYER R E, CHANG L, WILSON D H, FOURNIER D R, DUFFY D C. Lab Chip, 2012, 12(5): 977-985.
9. [9]
  COHEN L, WALT D R. Chem. Rev., 2019, 119(1): 293-321.
10. [10]
  RISSIN D M, FOURNIER D R, PIECH T, KAN C W, CAMPBELL T G, SONG L, CHANG L, RIVNAK A J, PATEL P P, PROVUNCHER G K, FERRELL E P, HOWES S C, PINK B A, MINNEHAN K A, WILSON D H, DUFFY D C. Anal. Chem., 2011, 83(6): 2279-2285.
11. [11]
  RANDALL J, MöRTBERG E, PROVUNCHER G K, FOURNIER D R, DUFFY D C, RUBERTSSON S, BLENNOW K, ZETTERBERG H, WILSON D H. Resuscitation, 2013, 84(3): 351-356.
12. [12]
  WILSON D H, RISSIN D M, KAN C W, FOURNIER D R, PIECH T, CAMPBELL T G, MEYER R E, FISHBURN M W, CABRERA C, PATEL P P, FREW E, CHEN Y, CHANG L, FERRELL E P, VON EINEM V, MCGUIGAN W, REINHARDT M, SAYER H, VIELSACK C, DUFFY D C. J. Lab. Autom., 2015, 21(4): 533-547.
13. [13]
  KAN C W, TOBOS C I, RISSIN D M, WIENER A D, MEYER R E, SVANCARA D M, COMPERCHIO A, WARWICK C, MILLINGTON R, COLLIER N, DUFFY D C. Lab Chip, 2020, 20(12): 2122-2135
14. [14]
  WEI G, ZHU J, HU H B, LIU J Q. Gene, 2021, 771: 145365.
15. [15]
  SINGHI A D, KOAY E J, CHARI S T, MAITRA A. Gastroenterology, 2019, 156(7): 2024-2040.
16. [16]
  SEIJO L M, PELED N, AJONA D, BOERI M, FIELD J K, SOZZI G, PIO R, ZULUETA J J, SPIRA A, MASSION P P, MAZZONE P J, MONTUENGA L M. J. Thorac. Oncol., 2019, 14(3): 343-357.
17. [17]
  PROKIC M D, RADOVANOVIC T B, GAVRIC J P, FAGGIO C. TrAC-Trends Anal. Chem., 2019, 111: 37-46.
18. [18]
  HOFMAN P, HEEKE S, ALIX-PANABIERES C, PANTEL K. Ann. Oncol., 2019, 30(9): 1448-1459.
19. [19]
  BRIDEL C, VAN WIERINGEN W N, ZETTERBERG H, TIJMS B M, TEUNISSEN C E, ALVAREZ-CERMENO J C, ANDREASSON U, AXELSSON M, BACKSTROM D C, BARTOS A, BJERKE M, BLENNOW K, BOXER A, BRUNDIN L, BURMAN J, CHRISTENSEN T, FIALOVA L, FORSGREN L, FREDERIKSEN J L, GISSLEN M, GRAY E, GUNNARSSON M, HALL S, HANSSON O, HERBERT M K, JAKOBSSON J, JESSEN-KRUT J, JANELIDZE S, JOHANNSSON G, JONSSON M, KAPPOS L, KHADEMI M, KHALIL M, KUHLE J, LANDEN M, LEINONEN V, LOGROSCINO G, LU C H, LYCKE J, MAGDALINOU N K, MALASPINA A, MATTSSON N, MEETER L H, MEHTA S R, MODVIG S, OLSSON T, PATERSON R W, PEREZ-SANTIAGO J, PIEHL F, PIJNENBURG Y A L, PYYKKO O T, RAGNARSSON O, ROJAS J C, CHRISTENSEN J R, SANDBERG L, SCHERLING C S, SCHOTT J M, SELLEBJERG F T, SIMONE I L, SKILLBACK T, STILUND M, SUNDSTROM P, SVENNINGSSON A, TORTELLI R, TORTORELLA C, TRENTINI A, TROIANO M, TURNER M R, VAN SWIETEN J C, VAGBERG M, VERBEEK M M, VILLAR L M, VISSER P J, WALLIN A, WEISS A, WIKKELSO C, WILD E J, GRP N F L. JAMA Neurol., 2019, 76(9): 1035-1048.
20. [20]
  HAMPEL H, O’BRYANT S E, MOLINUEVO J L, ZETTERBERG H, MASTERS C L, LISTA S, KIDDLE S J, BATRLA R, BLENNOW K. Nat. Rev. Neurol., 2018, 14(11): 639-652.
21. [21]
  BLENNOW K, ZETTERBERG H. J. Int. Med., 2018, 284(6): 643-663.
22. [22]
  KARIKARI T K, PASCOAL T A, ASHTON N J, JANELIDZE S, BENEDET A L, RODRIGUEZ J L, CHAMOUN M, SAVARD M, KANG M S, THERRIAULT J, SCHöLL M, MASSARWEH G, SOUCY J-P, HöGLUND K, BRINKMALM G, MATTSSON N, PALMQVIST S, GAUTHIER S, STOMRUD E, ZETTERBERG H, HANSSON O, ROSA-NETO P, BLENNOW K. Lancet Neurol., 2020, 19(5): 422-433.
23. [23]
  PREISCHE O, SCHULTZ S A, APEL A, KUHLE J, KAESER S A, BARRO C, GRäBER S, KUDER-BULETTA E, LAFOUGERE C, LASKE C, VöGLEIN J, LEVIN J, MASTERS C L, MARTINS R, SCHOFIELD P R, ROSSOR M N, GRAFF-RADFORD N R, SALLOWAY S, GHETTI B, RINGMAN J M, NOBLE J M, CHHATWAL J, GOATE A M, BENZINGER T L S, MORRIS J C, BATEMAN R J, WANG G, FAGAN A M, MCDADE E M, GORDON B A, JUCKER M, ALLEGRI R, AMTASHAR F, BATEMAN R, BENZINGER T, BERMAN S, BODGE C, BRANDON S, BROOKS W, BUCK J, BUCKLES V, CHEA S, CHHATWAL J, CHREM P, CHUI H, CINCO J, CLIFFORD J, CRUCHAGA C, D’MELLO M, DONAHUE T, DOUGLAS J, EDIGO N, EREKIN-TANER N, FAGAN A, FARLOW M, FARRAR A, FELDMAN H, FLYNN G, FOX N, FRANKLIN E, FUJII H, GANT C, GARDENER S, GHETTI B, GOATE A, GOLDMAN J, GORDON B, GRAFF-RADFORD N, GRAY J, GURNEY J, HASSENSTAB J, HIROHARA M, HOLTZMAN D, HORNBECK R, DIBARI S H, IKEUCHI T, IKONOMOVIC S, JEROME G, JUCKER M, KARCH C, KASUGA K, KAWARABAYASHI T, KLUNK W, KOEPPE R, KUDER-BULETTA E, LASKE C, LEE J-H, LEVIN J, MARCUS D, MARTINS R, MASON N S, MASTERS C, MAUE-DREYFUS D, MCDADE E, MONTOYA L, MORI H, MORRIS J, NAGAMATSU A, NEIMEYER K, NOBLE J, NORTON J, PERRIN R, RAICHLE M, RINGMAN J, ROH J H, SALLOWAY S, SCHOFIELD P, SHIMADA H, SHIROTO T, SHOJI M, SIGURDSON W, SOHRABI H, SPARKS P, SUZUKI K, SWISHER L, TADDEI K, WANG J, WANG P, WEINER M, WOLFSBERGER M, XIONG C, XU X, DOMINANTLY INHERITED ALZHEIMER N. Nat. Med., 2019, 25(2): 277-283.
24. [24]
  HOU Y, DAN X, BABBAR M, WEI Y, HASSELBALCH S G, CROTEAU D L, BOHR V A. Nat. Rev. Neurol., 2019, 15(10): 565-581.
25. [25]
  SOTO C, PRITZKOW S. Nat. Neurosci., 2018, 21(10): 1332-1340.
26. [26]
  SCHOONENBOOM N S M, PIJNENBURG Y A L, MULDER C, ROSSO S M, VAN ELK E J, VAN KAMP G J, VAN SWIETEN J C, SCHELTENS P. Neurology, 2004, 62(9): 1580.
27. [27]
  MULDER C, VERWEY N A, VAN DER FLIER W M, BOUWMAN F H, KOK A, VAN ELK E J, SCHELTENS P, BLANKENSTEIN M A. Clin. Chem., 2010, 56(2): 248-253.
28. [28]
  VAQUER-ALICEA J, DIAMOND M I. Annu. Rev. Biochem, 2019, 88(1): 785-810.
29. [29]
  BLENNOW K, HAMPEL H, WEINER M, ZETTERBERG H. Nat. Rev. Neurol., 2010, 6(3): 131-144.
30. [30]
  LI D, MIELKE M M. Neurol. Therapy, 2019, 8(Suppl 2): 73-82.
31. [31]
  OLSSON B, LAUTNER R, ANDREASSON U, ÖHRFELT A, PORTELIUS E, BJERKE M, HöLTTä M, ROSéN C, OLSSON C, STROBEL G, WU E, DAKIN K, PETZOLD M, BLENNOW K, ZETTERBERG H. Lancet Neurol., 2016, 15(7): 673-684.
32. [32]
  BLENNOW K. Neurol. Therapy, 2017, 6(1): 15-24.
33. [33]
  MIELKE M M, HAGEN C E, XU J, CHAI X, VEMURI P, LOWE V J, AIREY D C, KNOPMAN D S, ROBERTS R O, MACHULDA M M, JACK JR C R, PETERSEN R C, DAGE J L. Alzheimers. Dement., 2018, 14(8): 989-997.
34. [34]
  DE WOLF F, GHANBARI M, LICHER S, MCRAE-MCKEE K, GRAS L, WEVERLING G J, WERMELING P, SEDAGHAT S, IKRAM M K, WAZIRY R, KOUDSTAAL W, KLAP J, KOSTENSE S, HOFMAN A, ANDERSON R, GOUDSMIT J, IKRAM M A. Brain, 2020, 143(4): 1220-1232.
35. [35]
  DOBSON R, GIOVANNONI G. Eur. J. Neurol., 2019, 26(1): 27-40.
36. [36]
  CANTO E, BARRO C, ZHAO C, CAILLIER S J, MICHALAK Z, BOVE R, TOMIC D, SANTANIELLO A, HäRING D A, HOLLENBACH J, HENRY R G, CREE B A C, KAPPOS L, LEPPERT D, HAUSER S L, BENKERT P, OKSENBERG J R, KUHLE J. JAMA Neurol., 2019, 76(11): 1359-1366.
37. [37]
  MCCORD M R, BIGIO E H, KAM K L, FISCHER V, OBEIDIN F, WHITE C L, BRAT D J, MULLER W A, MAO Q. J. Neuropathol. Exp. Neurol., 2020, 79(6): 641-646.
38. [38]
  PENG Y, ZHANG Y, CHEN Z, PENG H, WAN N, ZHANG J, TANG J, WANG P, XIE Y, CAI Q, LIU S, ZHANG X, WANG C, YUAN H, LI T, WAN L, SHI Y, QIU R, KLOCKGETHER T, TANG B, LIAO W, JIANG H. Neurology, 2020, 95(22): e2977-e2987.
39. [39]
  LI Q F, DONG Y, YANG L, XIE J J, MA Y, DU Y C, CHENG H L, NI W, WU Z Y. Mol. Neurodegener., 2019, 14(1): 39.
40. [40]
  LUE L F, GUERRA A, WALKER D G. Neurol. Therapy, 2017, 6(1): 25-36.
41. [41]
  FOSSATI S, RAMOS CEJUDO J, DEBURE L, PIRRAGLIA E, SONE J Y, LI Y, CHEN J, BUTLER T, ZETTERBERG H, BLENNOW K, DE LEON M J. Alzheimers. Dement., 2019, 11(1): 483-492.
42. [42]
  PALMQVIST S, JANELIDZE S, QUIROZ Y T, ZETTERBERG H, LOPERA F, STOMRUD E, SU Y, CHEN Y, SERRANO G E, LEUZY A, MATTSSON-CARLGREN N, STRANDBERG O, SMITH R, VILLEGAS A, SEPULVEDA-FALLA D, CHAI X, PROCTOR N K, BEACH T G, BLENNOW K, DAGE J L, REIMAN E M, HANSSON O. JAMA, J. Am. Med. Assoc., 2020, 324(8): 772-781.
43. [43]
  LEHMANN S, DUMURGIER J, AYRIGNAC X, MARELLI C, ALCOLEA D, ORMAECHEA J F, THOUVENOT E, DELABY C, HIRTZ C, VIALARET J, GINESTET N, BOUAZIZ-AMAR E, LAPLANCHE J L, LABAUGE P, PAQUET C, LLEO A, GABELLE A, FOR THE ALZHEIMER’S DISEASE NEUROIMAGING I. Alzheimers Res. Ther., 2020, 12(1): 123.
44. [44]
  REBECCA S L, KIMBERLY M D, AHMEDIN J. CA Cancer J. Clin., 2018, 68(1): 7-30.
45. [45]
  SHI Y, GAO W, LYTLE N K, HUANG P, YUAN X, DANN A M, RIDINGER-SAISON M, DELGIORNO K E, ANTAL C E, LIANG G, ATKINS A R, ERIKSON G, SUN H, MEISENHELDER J, TERENZIANI E, WOO G, FANG L, SANTISAKULTARM T P, MANOR U, XU R, BECERRA C R, BORAZANCI E, VON HOFF D D, GRANDGENETT P M, HOLLINGSWORTH M A, LEBLANC M, UMETSU S E, COLLISSON E A, SCADENG M, LOWY A M, DONAHUE T R, REYA T, DOWNES M, EVANS R M, WAHL G M, PAWSON T, TIAN R, HUNTER T. Nature, 2019, 569(7754): 131-135.
46. [46]
  WEI P, WU F, KANG B, SUN X, HESKIA F, PACHOT A, LIANG J, LI D. J. Extracell. Vesicles., 2020, 9(1): 1809765.
47. [47]
  WILSON D H, HANLON D W, PROVUNCHER G K, CHANG L, SONG L, PATEL P P, FERRELL E P, LEPOR H, PARTIN A W, CHAN D W, SOKOLL L J, CHELI C D, THIEL R P, FOURNIER D R, DUFFY D C. Clin. Chem., 2011, 57(12): 1712-1721.
48. [48]
  KEEGAN A, RICCIUTI B, GARDEN P, COHEN L, NISHIHARA R, ADENI A, PAWELETZ C, SUPPLEE J, JäNNE P A, SEVERGNINI M, AWAD M M, WALT D R. J. ImmunoTher. Cancer, 2020, 8(2): e000678.
49. [49]
  ZHOU B, XU K, ZHENG X, CHEN T, WANG J, SONG Y, SHAO Y, ZHENG S. Signal. Transduct. Tar., 2020, 5(1): 144.
50. [50]
  BORIACHEK K, MASUD M K, PALMA C, PHAN H P, YAMAUCHI Y, HOSSAIN M S A, NGUYEN N T, SALOMON C, SHIDDIKY M J A. Anal. Chem., 2019, 91(6): 3827-3834.
51. [51]
  TóTH K, BARTáK B K, TULASSAY Z, MOLNáR B. Expert Rev. Mol. Diagn., 2016, 16(2): 239-252.
52. [52]
  FAUCI A S, MORENS D M. New Engl. J. Med., 2012, 366(5): 454-461.
53. [53]
  CABRERA C, CHANG L, STONE M, BUSCH M, WILSON D H. Clin. Chem., 2015, 61(11): 1372-1380.
54. [54]
  CHANG L, SONG L, FOURNIER D R, KAN C W, PATEL P P, FERRELL E P, PINK B A, MINNEHAN K A, HANLON D W, DUFFY D C, WILSON D H. J. Virol. Methods, 2013, 188(1): 153-160.
55. [55]
  PASSAES C, DELAGREVERIE H M, AVETTAND-FENOEL V, DAVID A, MONCEAUX V, ESSAT A, MüLLER-TRUTWIN M, DUFFY D, DE CASTRO N, ROUZIOUX C, MOLINA J-M, MEYER L, DELAUGERRE C, SAEZ-CIRION A. medRxiv, 2021.
56. [56]
  AHMAD R, XIE L, PYLE M, SUAREZ M F, BROGER T, STEINBERG D, AME S M, LUCERO M G, SZUCS M J, MACMULLAN M, BERVEN F S, DUTTA A, SANVICTORES D M, TALLO V L, BENCHER R, EISINGER D P, DHINGRA U, DEB S, ALI S M, MEHTA S, FAWZI W W, RILEY I D, SAZAWAL S, PREMJI Z, BLACK R, MURRAY C J L, RODRIGUEZ B, CARR S A, WALT D R, GILLETTE M A. Sci. Transl. Med., 2019, 11(515): eaaw8287.
57. [57]
  NORMAN M, GILBOA T, OGATA A F, MALEY A M, COHEN L, BUSCH E L, LAZAROVITS R, MAO C P, CAI Y, ZHANG J, FELDMAN J E, HAUSER B M, CARADONNA T M, CHEN B, SCHMIDT A G, ALTER G, CHARLES R C, RYAN E T, WALT D R. Nat. Biomed. Eng., 2020, 4(12): 1180-1187.
58. [58]
  WIERSINGA W J, RHODES A, CHENG A C, PEACOCK S J, PRESCOTT H C. JAMA, J. AM. Med. Assoc., 2020, 324(8): 782-793.
59. [59]
  JAROLIM P, PATEL P P, CONRAD M J, CHANG L, MELENOVSKY V, WILSON D H. Clin. Chem., 2015, 61(10): 1283-1291.
60. [60]
  RIVIèRE E, PASCAUD J, VIRONE A, DUPRé A, LY B, PAOLETTI A, SEROR R, TCHITCHEK N, MINGUENEAU M, SMITH N, DUFFY D, CASSARD L, CHAPUT N, PENGAM S, GAUTTIER V, POIRIER N, MARIETTE X, NOCTURNE G. Arthritis Rheumatol., 2021, 73(4): 631-640.
61. [61]
  COHEN L, HARTMAN M R, AMARDEY-WELLINGTON A, WALT D R. Nucleic Acids Res., 2017, 45(14): e137.
62. [62]
  LI Z, HAYMAN R B, WALT D R. J. Am. Chem. Soc., 2008, 130(38): 12622-12623.
63. [63]
  WANG X, COHEN L, WANG J, WALT D R. J. Am. Chem. Soc., 2018, 140(51): 18132-18139.
64. [64]
  WU S G, CHANG T H, LIU Y N, SHIH J Y. Cancers (Basel), 2019, 11(2): 265.
1. [1]
  Siyi ZHONG , Xiaowen LIN , Jiaxin LIU , Ruyi WANG , Tao LIANG , Zhengfeng DENG , Ao ZHONG , Cuiping HAN . Targeting imaging and detection of ovarian cancer cells based on fluorescent magnetic carbon dots. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1483-1490. doi: 10.11862/CJIC.20240093
2. [2]
  Yue WANG , Zhizhi GU , Jingyi DONG , Jie ZHU , Cunguang LIU , Guohan LI , Meichen LU , Jian HAN , Shengnan CAO , Wei WANG . Effects of kelp-derived carbon dots on embryonic development of zebrafish. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1209-1217. doi: 10.11862/CJIC.20230423
3. [3]
  Jinlong YAN , Weina WU , Yuan WANG . A simple Schiff base probe for the fluorescent turn-on detection of hypochlorite and its biological imaging application. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1653-1660. doi: 10.11862/CJIC.20240154
4. [4]
  Jingwen Wang , Minghao Wu , Xing Zuo , Yaofeng Yuan , Yahao Wang , Xiaoshun Zhou , Jianfeng Yan . Advances in the Application of Electrochemical Regulation in Investigating the Electron Transport Properties of Single-Molecule Junctions. University Chemistry, 2025, 40(3): 291-301. doi: 10.12461/PKU.DXHX202406023
5. [5]
  Chun-Lin Sun , Yaole Jiang , Yu Chen , Rongjing Guo , Yongwen Shen , Xinping Hui , Baoxin Zhang , Xiaobo Pan . Construction, Performance Testing, and Practical Applications of a Home-Made Open Fluorescence Spectrometer. University Chemistry, 2024, 39(5): 287-295. doi: 10.3866/PKU.DXHX202311096
6. [6]
  Fei Xie , Chengcheng Yuan , Haiyan Tan , Alireza Z. Moshfegh , Bicheng Zhu , Jiaguo Yu . d带中心调控过渡金属单原子负载COF吸附O₂的理论计算研究. Acta Physico-Chimica Sinica, 2024, 40(11): 2407013-. doi: 10.3866/PKU.WHXB202407013
7. [7]
  Mi Wen , Baoshuo Jia , Yongqi Chai , Tong Wang , Jianbo Liu , Hailong Wu . Improvement of Fluorescence Quantitative Analysis Experiment: Simultaneous Determination of Rhodamine 6G and Rhodamine 123 in Food Using Chemometrics-Assisted Three-Dimensional Fluorescence Method. University Chemistry, 2025, 40(4): 390-398. doi: 10.12461/PKU.DXHX202405147
8. [8]
  Jiali CHEN , Guoxiang ZHAO , Yayu YAN , Wanting XIA , Qiaohong LI , Jian ZHANG . Machine learning exploring the adsorption of electronic gases on zeolite molecular sieves. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 155-164. doi: 10.11862/CJIC.20240408
9. [9]
  Liang TANG , Jingfei NI , Kang XIAO , Xiangmei LIU . Synthesis and X-ray imaging application of lanthanide-organic complex-based scintillators. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1892-1902. doi: 10.11862/CJIC.20240139
10. [10]
  Yan ZHAO , Xiaokang JIANG , Zhonghui LI , Jiaxu WANG , Hengwei ZHOU , Hai GUO . Preparation and fluorescence properties of Eu³⁺-doped CaLaGaO₄ red-emitting phosphors. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1861-1868. doi: 10.11862/CJIC.20240242
11. [11]
  Donghui PAN , Yuping XU , Xinyu WANG , Lizhen WANG , Junjie YAN , Dongjian SHI , Min YANG , Mingqing CHEN . Preparation and in vivo tracing of ⁶⁸Ga-labeled PM_2.5 mimetic particles for positron emission tomography imaging. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 669-676. doi: 10.11862/CJIC.20230468
12. [12]
  Fang Niu , Rong Li , Qiaolan Zhang . Analysis of Gas-Solid Adsorption Behavior in Resistive Gas Sensing Process. University Chemistry, 2024, 39(8): 142-148. doi: 10.3866/PKU.DXHX202311102
13. [13]
  Xinyu Liu , Weiran Hu , Zhengkai Li , Wei Ji , Xiao Ni . Algin Lab: Surging Luminescent Sea. University Chemistry, 2024, 39(5): 396-404. doi: 10.3866/PKU.DXHX202312021
14. [14]
  Pingwei Wu . Application of Diamond Software in Simplex Teaching. University Chemistry, 2024, 39(3): 118-121. doi: 10.3866/PKU.DXHX202311043
15. [15]
  Endong YANG , Haoze TIAN , Ke ZHANG , Yongbing LOU . Efficient oxygen evolution reaction of CuCo₂O₄/NiFe-layered bimetallic hydroxide core-shell nanoflower sphere arrays. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 930-940. doi: 10.11862/CJIC.20230369
16. [16]
  Liang MA , Honghua ZHANG , Weilu ZHENG , Aoqi YOU , Zhiyong OUYANG , Junjiang CAO . Construction of highly ordered ZIF-8/Au nanocomposite structure arrays and application of surface-enhanced Raman spectroscopy. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1743-1754. doi: 10.11862/CJIC.20240075
17. [17]
  Jianjun Liu , Xue Yang , Chi Zhang , Xueyu Zhao , Zhiwei Zhang , Yongmei Chen , Qinghong Xu , Shao Jin . Preparation and Fluorescence Characterization of CdTe Semiconductor Quantum Dots. University Chemistry, 2024, 39(7): 307-315. doi: 10.3866/PKU.DXHX202311031
18. [18]
  Zishuo Yi , Peng Liu , Yan Xu . Fluorescent “Chameleon”: A Popular Science Experiment Based on Dynamic Luminescence. University Chemistry, 2024, 39(9): 304-310. doi: 10.12461/PKU.DXHX202311079
19. [19]
  Zhongxin YU , Wei SONG , Yang LIU , Yuxue DING , Fanhao MENG , Shuju WANG , Lixin YOU . Fluorescence sensing on chlortetracycline of a Zn-coordination polymer based on mixed ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2415-2421. doi: 10.11862/CJIC.20240304
20. [20]
  Zijuan LI , Xuan LÜ , Jiaojiao CHEN , Haiyang ZHAO , Shuo SUN , Zhiwu ZHANG , Jianlong ZHANG , Yanling MA , Jie LI , Zixian FENG , Jiahui LIU . Synthesis of visual fluorescence emission CdSe nanocrystals based on ligand regulation. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 308-320. doi: 10.11862/CJIC.20240138

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(731)
HTML views(135)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142