Citation: GONG Shao-Hua, PAN Wei, LI Na, TANG Bo. Progress of Portable Biosensors for Quantitative Detection of Cancer Biomarkers[J]. Chinese Journal of Analytical Chemistry, ;2022, 50(11): 1599-1612. doi: 10.19756/j.issn.0253-3820.210507 shu

Progress of Portable Biosensors for Quantitative Detection of Cancer Biomarkers

Institute of Molecular and Nano Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, College of Chemistry, Chemical Engineering and Materials Science, Shandong Normal University, Jinan 250014, China

Corresponding author: LI Na, lina@sdnu.edu.cn
Received Date: 17 May 2021
Revised Date: 23 November 2021

Fund Project: Supported by the National Natural Science Foundation of China (Nos.21874086, 21775094) and the Youth Innovation Science and Technology Program of Higher Education Institution of Shandong Province, China (No.2019KJC022).

Accurate detection of cancer biomarkers plays a significant role in early diagnosis of cancer and improving the survival rate of cancer patients. Liquid biopsy can non-invasively and repeatedly detect cancer biomarkers in human body fluid and holds great promise for early diagnosis of cancer. Liquid biopsy based on simple signal output can obtain detection result via simple operation and thus hopefully realizing on-site detection, showing great potential in early screening, prognosis and monitoring of therapeutic effect of cancer. In this review, we focused on the recent advances of portable and quantitative detection of cancer biomarkers and summarized the detection strategies based on portable pressure meter, volumetric bar-chart chip, personal glucose meter, thermal meter, pH meter and digital multimeter. In addition, the perspectives and challenges in this field were also discussed.
- Cancer biomarker,
- Biosensor,
- Quantitative detection,
- Portable equipment,
- Review
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