Citation: ZHANG Hao-Chen, GUO Yong-Ming. Advances of Carbon Quantum Dots for Fluorescence Turn-on Detection of Reductive Small Biomolecules[J]. Chinese Journal of Analytical Chemistry, ;2021, 49(1): 14-23. doi: 10.19756/j.issn.0253-3820.201349 shu

Advances of Carbon Quantum Dots for Fluorescence Turn-on Detection of Reductive Small Biomolecules

ZHANG Hao-Chen ,
GUO Yong-Ming ^,

School of Chemistry and Materials Science, Nanjing University of Information Science & Technology, Nanjing 210044, China

Corresponding author: GUO Yong-Ming, chinahenangm@163.com
Received Date: 15 June 2020
Revised Date: 18 September 2020

Fund Project: Supported by the Startup Foundation for Introducing Talent of NUIST (No. 2018r056), the Innovation and Entrepreneurship Training Program for College Students of NUIST (No. 201910300209) and the Foundation of NUIST-UoR International Research Institute.

Small biomolecules in human body involve in many important life activities, especially some small reductive biomolecules, and play important roles in maintaining human health and resisting diseases. Therefore, the rapid and accurate detection of small reductive biomolecules is of great significance. The fluorescence turn-on detection is a sensitive detection method with ease of operation. Carbon quantum dots (CQDs) are a novel zero-dimensional fluorescent carbon nanomaterial, which exhibit many advantages including good biocompatibility, low toxicity, ease of fabrication, low cost, good photostability and high fluorescence quantum yield, therefore, CQDs have great potential in the fluorescence turn-on detection of small biomolecules. In this paper, we summarized the development of CQDs in fluorescence turn-on detection of glucose, ascorbic acid, dopamine, biothiols and uric acid in recent three years. Finally, we discussed the opportunities and challenges of CQDs in the fluorescence turn-on detection of these small biomolecules.
- Carbon quantum dots,
- Small biomolecules,
- Fluorescence,
- Detection,
- Review
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