Citation: XUE Yi-Fei, XIAO Tong-Fang, JIANG Ya-Nan, . Progress of in Vivo Electrochemical Analysis of Brain Neurochemistry[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(10): 1443-1454. doi: 10.19756/j.issn.0253-3820.191467 shu

Progress of in Vivo Electrochemical Analysis of Brain Neurochemistry

XUE Yi-Fei ^1,2, ,
XIAO Tong-Fang ¹ ,
JIANG Ya-Nan ^1,2 ,
^1,2 ,
^1,2 ,
^1,2

1.
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China;
2.
University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 30 July 2019
Revised Date: 16 August 2019

Fund Project: This work was supported by the National Natural Science Foundation of China (Nos. 21790390, 21790391, 21621062, 21874139) and the National Key Research and Develop Program of China (No.2018YFE0200800).

Brain science has become one of the most advanced interdisciplinary research topics. Analysis of brain neurochemistry has attracted great attention in both neuroscience and chemistry, because it provides a powerful tool to understand the physiological and pathological progresses of the brain at a molecular level. For neurochemical monitoring, electrochemical methods come to prominence with high selectivity, sensitivity, spatiotemporal resolution and designable electrode/solution interface to match the pursuit for in vivo analysis of brain neurochemistry. This review summarizes the development of electrochemical approaches toward brain neurochemistry research from both principal and practical perspectives. In addition, future trends of in vivo electrochemical analysis are prospected.
- In vivo electrochemistry,
- Brain neurochemistry,
- In vivo measurement,
- Review
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