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Citation: WANG Meng, ZHU Li, XIAO Na, JI Cheng-Wei. Investigation of Generation Method of Double Emulsion Broplets Based on Compositional Microfluidic Chip[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(9): 1352-1358. doi: 10.19756/j.issn.0253-3820.191347 shu

Investigation of Generation Method of Double Emulsion Broplets Based on Compositional Microfluidic Chip

School of Mechanical Engineering, Nanjing University of Science and Technology, Microsystems Laboratory, Nanjing 210094, China

Received Date: 21 June 2019
Revised Date: 17 July 2019

Fund Project: This work was supported by the National Natural Science Foundation of China (No. 51705257).

A method was developed for producing double emulsion droplets based on a compositional microfluidic chip that was consisted of a T-micro connector, a cross-micro connector and a glass capillary. T-junction microfluidic chip could fabricate high throughput and uniform oil-in-water (O/W) and water-in-oil (W/O) droplets without hydrophobic or hydrophilic treatments. T-junction microfluidic chip was reusable and highly reliable. The process of generation droplet was simulated by COMSOL in 3D simulation model. The T-junction microfluidic chip was used to generate W/O droplets, and it was found that the high throughput and uniform W/O droplets could be obtained by adjusting the phase flow. Besides, the W/O droplets with different colors were obtained by a microfluidic chip comprised of cross-micro connector and glass capillary. Based on the above experiments, a combination microfluidic chip of T-micro connector, cross-micro connector and glass capillary was constructed. The constructed chip could produce W/O/W double emulsion droplets by adjusting the phase flows. This method offered a simple, low-cost way to produce double emulsion droplets in a short time without professional facilities.
- Double emulsions droplets,
- Microfluidic chip,
- COMSOL simulation
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