Citation: LIAN Jiao-Yuan, ZHENG Su-Xia, XU Zhong-Bin, RUAN Xiao-Dong. Study on Co-flow Effect on Janus Droplet Generation Based on Step Emulsification[J]. Chinese Journal of Analytical Chemistry, ;2020, 48(1): 57-65. doi: 10.19756/j.issn.0253-3820.191343 shu

Study on Co-flow Effect on Janus Droplet Generation Based on Step Emulsification

1.
Institute of Process Equipment, College of Energy Engineering, Zhejiang University, Hangzhou 310027, China;
2.
Hangzhou Vocational and Technical College, Hangzhou 310018, China;
3.
The State Key Laboratory of Fluid Power and Mechatronic Systems, Zhejiang University, Hangzhou 310027, China

Received Date: 20 June 2019
Revised Date: 15 July 2019

Fund Project: This work was supported by the National Natural Science Foundation of China (No. 21676244).

Continuous phase co-flow can increase the throughput and control flexibility of step emulsification, and has an important effect on droplet microfluidic. This study built a multi-channel step emulsification device to generate Janus droplets and to study the effects of both continuous phase co-flow and dispersed phase flow on the generation of Janus droplets. Firstly, Janus droplets were successfully prepared by the device, and the generation stability was optimized by using glass capillaries instead of microcapillary film based on their different wall contact angles at the channel outlet. Secondly, the effect on the generation of Janus droplet was studied by changing the flows of the continuous and dispersed phases, respectively. The result showed that the Janus droplets generation stability was almost independent of the two phases flow rates. When the continuous phase co-flow rate increased, the resulted Janus droplet diameter decreased, and the generation frequency increased. The droplet diameter decreased by 61% with the co-flow rate increasing from 0.01 mL/h to 30 mL/h. When the flow rate of dispersed phase increased, both the diameter and generation frequency of the generated Janus droplet increased. The droplet diameter increased by 63% as the dispersed phase flow increased from 0.1 mL/h to 3.0 mL/h. Within the scope of this study, the diameter and the generation frequency of the two components Janus droplet could be controlled in 638-1640 μm and 0.02-2.2 Hz, respectively. In addition, three-component droplets were generated successfully and steadily by a three-component droplet generation chip which was prepared based on the two-component droplet generation device. By changing the two phase flow rates, the droplet diameter and frequency could also be tuned on-line. When the co-flow rate increased from 1 mL/h to 30 mL/h, the droplet diameter decreased by 45%, and when the dispersed phase flow increased from 0.1 mL/h to 5 mL/h, the droplet diameter increased by 89%. The generation frequencies increased accordingly. Additionally, it was found that the co-flow effect had a greater impact on the generation of three-component droplet due to the result that the three-component droplet diameter changed greater than the two-component droplet when changing both the continuous and dispersed phase flows. Therefore, in this study, two-component and three-component droplets were generated by co-flowing step emulsification, which could be controlled on-line by changing the co-flow rate. The results of this study provided a basis and method for micro and trace research of chemical and analysis industry.
- Co-flow,
- Microfluidic,
- Janus droplet,
- Step emulsification,
- Chemical industry,
- Analysis
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沈阳化工大学材料科学与工程学院沈阳 110142