Citation: GUO Xiang-Yu, HUANG Xue-Mei, ZHAI Jun-Feng, BAI Hua, LI Xiao-Xu, MA Xiao-Xiao, MA Qiang. Research Advances in Ambient Ionization and Miniature Mass Spectrometry[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(3): 335-346. doi: 10.19756/j.issn.0253-3820.181626 shu

Research Advances in Ambient Ionization and Miniature Mass Spectrometry

1.
Chinese Academy of Inspection and Quarantine, Beijing 100176, China;
2.
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China;
3.
School of Mechanical and Electric Engineering, Soochow University, Suzhou 215021, China;
4.
Department of Precision Instrument, Tsinghua University, Beijing 100084, China

Received Date: 3 October 2018
Revised Date: 25 November 2018

Fund Project: This work was supported by the National Key Research and Development Program of China (No. 2016YFF0203704).

The development and application of ambient ionization and miniature mass spectrometry are current research focus in chemical measurements. The analytical technology based on ambient ionization coupled with miniature mass spectrometry can bypass chromatographic separation and eliminate or simplify sample pretreatment process. The protocol breaks through the drawbacks of labor-intensive and time-consuming of traditional analytical methodologies, and can be used for the rapid and on-site analysis with high sensitivity and high throughput. In this paper, research progress of ambient ionization and miniature mass spectrometry as well as their applications in the fields of food safety, consumer product safety, public security, life science and environmental monitoring have been reviewed, and future trends and prospective have been discussed, which may provide a technical guidance for the researchers engaged in relevant fields.
- Ambient ionization,
- Miniature mass spectrometry,
- Review
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