Citation: JIN Xiao-Wei, LI Zhe-Yu, XU Pian-Pian, ZHANG Xiao-Yan, REN Nan-Qi, VITALIY V. Kurilenko, SUN Kai. Advances in Microfluidic Biosensors Based on Luminescent Bacteria[J]. Chinese Journal of Analytical Chemistry, ;2019, 47(2): 181-190. doi: 10.19756/j.issn.0253-3820.181320 shu

Advances in Microfluidic Biosensors Based on Luminescent Bacteria

1.
State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China;
2.
Institute of Earth Sciences, Saint-Petersburg State University, Saint-Petersburg 199034, Russian Federation

Received Date: 12 May 2018
Revised Date: 7 November 2018

Fund Project: This work was supported by the National Natural Science Foundation of China (No. 61674046).

Luminescent bacteria are a kind of bacteria which emit visible light at 450 nm-490 nm. Its luminous intensity decreases with the increase of the concentration of toxic substances in test solution. The methods hased on luminescent bacteria are widely used in acute toxicity analysis of water quality because of its sensitiveness, quickness and inexpensiveness. With the rapid development of genetic modification technology, non-luminescent bacteria can also produce visible light by planting luminescent genes, which makes the application field of luminescent bacteria widen. In recent years, biosensors based on luminescent bacteria have attracted more and more attention, and the reports of bioluminescence biosensors based on microfluidic systems are increasing day by day. Based on the characteristics and mechanism of luminescent bacteria, this review introduced their applications in the environmental monitoring, and summarized several new bioluminescence sensors.
- Luminescent bacteria,
- Acute toxicity,
- Environmental pollutant,
- Microfluidic,
- Biosensor,
- Review
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沈阳化工大学材料科学与工程学院沈阳 110142