Citation: OTHMAN Karwan ABDULMAJED, Jin-Jin CAI, Rui XIE, Xin-Ran ZHOU, Hui YAO, Nian-Yu HUANG. Synthesis and Absolute Configuration of(2R, 3S, 4Z, 6Z)-1, 3-bis(benzyloxy)-8-chloro-7-((E)-(2-(2, 4-dinitrophenyl)hydrazono)methyl)octa-4, 6-dien-2-ol[J]. Chinese Journal of Structural Chemistry, ;2020, 39(10): 1781-1787. doi: 10.14102/j.cnki.0254–5861.2011–2768 shu

Synthesis and Absolute Configuration of(2R, 3S, 4Z, 6Z)-1, 3-bis(benzyloxy)-8-chloro-7-((E)-(2-(2, 4-dinitrophenyl)hydrazono)methyl)octa-4, 6-dien-2-ol

a.
Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, China
b.
Department of Manufacturing and Industrial Engineering, Faculty of Engineering, Koya University, Koya KOY45, 45001, Kurdistan Region-F.R. Iraq

Corresponding author: Hui YAO, yaohui@ctgu.edu.cn Nian-Yu HUANG, huangny@ctgu.edu.cn
Received Date: 22 February 2020
Accepted Date: 8 April 2020

Fund Project: the National Natural Science Foundation of China 21602123

Figures(4)

Lewis acid-catalyzed [1,3]-sigmatropic O→C rearrangement was used to synthesize C-glycosides derivatives. The structure of the target compound was characterized by NMR and HR-ESI-MS, and its absolute configuration was confirmed. Compound 8 (C₂₉H₂₉ClN₄O₇): monoclinic system, space group P2₁2₁2₁, a = 6.1484(2), b = 12.3625(3), c = 37.0127(8) Å, V = 2813.32(13) Å³, Z = 4, F(000) = 1216.0, D_c = 1.372 g/cm³, μ = 1.662 mm⁻¹, R = 0.0522 and wR = 0.1358 for 5611 independent reflections (R_int = 0.0778) and 5169 observed ones (I > 2σ(I)).
- X-ray diffraction,
- crystal structure,
- absolute configuration,
- conjugated aliphatic imine,
- cytotoxity
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