Citation: SU Zhe, QIN Wenjing, BAI Lei, SUN Pengfei, YU Changmin, FAN Quli, LI Lin. Research Progress on Bioimaging with the Second Near-infrared Fluorescence Probes[J]. Chinese Journal of Applied Chemistry, ;2019, 36(2): 123-136. doi: 10.11944/j.issn.1000-0518.2019.02.180116 shu

Research Progress on Bioimaging with the Second Near-infrared Fluorescence Probes

  • Corresponding author: YU Changmin, iamcmyu@njtech.edu.cn LI Lin, iamlli@njtech.edu.cn
  • Received Date: 16 April 2018
    Revised Date: 11 June 2018
    Accepted Date: 4 July 2018

    Fund Project: the National Natural Science Foundation of China 81672508the Jiangsu Provincial Foundation for Distinguished Young Scholars BK20170041the National Natural Science Foundation of China 61505076Supported by the National Natural Science Foundation of China(No.81672508, No.61505076, No.21708034), the Jiangsu Provincial Foundation for Distinguished Young Scholars(No.BK20170041)the National Natural Science Foundation of China 21708034

Figures(13)

  • Due to simple operation, high resolution and real-time imaging, fluorescence technology has been widely used in detection and bioimaging. The second near-infrared window dyes(NIR-Ⅱ, 1000~1700 nm) have longer emission wavelength, less interference with light scattering and tissue autofluorescence, resulting in higher temporal and spatial resolution and deeper imaging depth in tissue imaging. In this review, we mainly introduce the designed mechanism and research progress in bioimaging based on NIR-Ⅱ dyes, and further give an outlook in the following studies.
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