Citation: HAN Xu, DING Guanyu, DONG Qing, YANG Xiuyun, LI Dan, DU Yan, WANG Erkang. Research Progress of Nano-Gene Carriers Based on Liposomes[J]. Chinese Journal of Applied Chemistry, ;2018, 35(7): 735-744. doi: 10.11944/j.issn.1000-0518.2018.07.180031 shu

Research Progress of Nano-Gene Carriers Based on Liposomes

HAN Xu ^a ,
DING Guanyu ^a ,
DONG Qing ^a ,
^a ,
YANG Xiuyun ^a,, ,
LI Dan ^b,, ,
DU Yan ^b,, ,
WANG Erkang ^b,,

a.
School of Chemistry and Environmental Engineering, Changchun University of Science and Technology, Changchun 130022, China
b.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Corresponding author: YANG Xiuyun, yangxiuyun@cust.edu.cn LI Dan, lidan@ciac.ac.cn DU Yan, duyan@ciac.ac.cn WANG Erkang, ekwang@ciac.ac.cn
Received Date: 30 January 2018
Revised Date: 15 March 2018
Accepted Date: 3 May 2018

Figures(7)

Gene therapy is a method for curing diseases caused by genetic defects and anomalies through introducing normal foreign genes into targeted cells. Efficient and sustained expression of foreign genes in cells is the decisive factor in gene therapy, which is significantly relied on the vectors used in the treatment. With the development of science and technology, the research of liposome/nanocomposites as gene carriers has widely attracted people's attention, due to the following advantages:versatile functions, easy surface modification, good biocompatibility, high transfection efficiency. Herein, the structure of liposome bilayer was introduced and the complexes of magnetic nanoparticles, gold nanoparticles, quantum dots, chitosan, upconversion nanoparticles with liposomes as gene carriers have been reviewed and prospected.
- liposome,
- gene carrier,
- nanomaterials
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