Citation: WU Zhongtao, ZHANG Lei, SHAO Baiqi, LIU Kai. Recent Research Progress on Biomacromolecular Thermotropic Liquid Crystals[J]. Chinese Journal of Applied Chemistry, ;2018, 35(2): 123-128. doi: 10.11944/j.issn.1000-0518.2018.02.170427 shu

Recent Research Progress on Biomacromolecular Thermotropic Liquid Crystals

WU Zhongtao ^a ,
ZHANG Lei ^a,, ,
SHAO Baiqi ^b,, ,
LIU Kai ^b,,

a.
Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, Shandong 266042, China
b.
State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Corresponding author: ZHANG Lei, leizhang0216@hotmail.com SHAO Baiqi, bqshao@ciac.ac.cn LIU Kai, kai.liu@ciac.ac.cn
Received Date: 27 November 2017
Revised Date: 22 December 2017
Accepted Date: 22 December 2017

Fund Project: the National Natural Science Foundation of China 21704099Supported by the National Natural Science Foundation of China(No.21704099)

Figures(4)

Biomacromolecules, such as DNA, protein and virus, can only undergo thermal degradation because their dimensions exceed the range of their intermolecular forces. Hence the formation of solvent-free biomacromolecular liquid and liquid crystal materials remains a significant challenge. Here, we briefly introduce the preparation and characterization of solvent-free biomacromolecular liquid crystal materials. Lamellar mesophases of solvent-free thermotropic liquid crystals are formed by electrostatic complexation of biomacromolecules and oppositely charged surfactants. These thermotropic liquid crystals retain the ordering and fluidity of biomolecules, providing great opportunities for their technical applications in water-free environments.
- biomacromolecule,
- thermotropic liquid crystal,
- surfactant,
- electrostatic force
1. [1]
  Nakata M, Zanchetta G, Chapman B D. End-to-End Stacking and Liquid Crystal Condensation of 6 to 20 Base Pair DNA Duplexes[J]. Science, 2007,318(5854):1276-1279. doi: 10.1126/science.1143826
2. [2]
  Koltover I, Salditt T, Rädler J O. An Inverted Hexagonal Phase of Cationic Liposome-DNA Complexes Related to DNA Release and Delivery[J]. Science, 1998,281(5373):78-81. doi: 10.1126/science.281.5373.78
3. [3]
  Hamley I W. Liquid Crystal Phase Formation by Biopolymers[J]. Soft Matter, 2010,6(9):1863-1871. doi: 10.1039/b923942a
4. [4]
  Bangham A D. Liposome Letters[M]. New York:Academic Press, 1983.
5. [5]
  Strzelecka T E, Davidson M W, Rill R L. Multiple Liquid Crystal Phases of DNA at High Concentrations[J]. Nature, 1988,331(6155):457-461. doi: 10.1038/331457a0
6. [6]
  Livolant F. Ordered Phases of DNA in vivo and in vitro[J]. Physica A, 1991,176(1):117-137. doi: 10.1016/0378-4371(91)90436-G
7. [7]
  Livolant F, Bouligand Y. Liquid Crystalline Phases Given by Helical Biological Polymers(DNA, PBLG and xanthan). Columnar Textures[J]. J Phys Fr, 1986,47(10):1813-1827. doi: 10.1051/jphys:0198600470100181300
8. [8]
  Yu S M, Conticello V P, Zhang G. Smectic Ordering in Solutions and Films of a Rod-Like Polymer Owing Tomonodispersity of Chain Length[J]. Nature, 1997,389(6647):167-170. doi: 10.1038/38254
9. [9]
  Dogic Z, Fraden S. Ordered Phases of Filamentous Viruses[J]. Curr Opin Colloid Interface Sci, 2006,11(1):47-55. doi: 10.1016/j.cocis.2005.10.004
10. [10]
  Chung W J, Oh J W, Kwak K. Biomimetic Self-Templating Supramolecular Structures[J]. Nature, 2011,478(7369):364-368. doi: 10.1038/nature10513
11. [11]
  Liu K, Chen D, Marcozzi A. Thermotropic Liquid Crystals from Biomacromolecules[J]. Proc Natl Acad Sci USA, 2014,111(52):18596-18600. doi: 10.1073/pnas.1421257111
12. [12]
  Perriman A W, Cölfen H, Hughes R W. Solvent-Free Protein Liquids and Liquid Crystals[J]. Angew Chem Int Ed, 2009,48(34):6242-6246. doi: 10.1002/anie.200903100
13. [13]
  Liu K, Shuai M, Chen D. Solvent-free Liquid Crystals and Liquids from DNA[J]. Chem Eur J, 2015,21(13):4898-4903. doi: 10.1002/chem.201500159
14. [14]
  Zhang L, Maity S, Liu K. Nematic DNA Thermotropic Liquid Crystals with Photoresponsive Mechanical Properties[J]. Small, 2017,13(34)1701207. doi: 10.1002/smll.v13.34
15. [15]
  Liu K, Pesce D, Ma C. Solvent-Free Liquid Crystals and Liquids Based on Genetically Engineered Supercharged Polypeptides with High Elasticity[J]. Adv Mater, 2015,27(15):2459-2465. doi: 10.1002/adma.201405182
16. [16]
  Ramamoorthy A. Thermotropic Liquid Crystals[M]. Wiley, 2007: 269-274.
17. [17]
  Radler J O, Salditt T, Safinya C R. Structure of DNA-Cationic Liposome Complexes:DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing Regimes[J]. Science, 1997,275(5301):810-814. doi: 10.1126/science.275.5301.810
18. [18]
  Liu K, Zheng L, Liu Q. Nucleic Acid Chemistry in the Organic Phase:From Functionalized Oligonucleotides to DNA Side Chain Polymers[J]. J Am Chem Soc, 2014,136(40):14255-14262. doi: 10.1021/ja5080486
19. [19]
  Strzelecka T E, Davidson M W, Rill R L. Multiple Liquid Crystal Phases of DNA at High Concentrations[J]. Nature, 1988,331(6155):457-460. doi: 10.1038/331457a0
20. [20]
  Liu K, Varghese J, Gerasimov J Y. Controlling the Volatility of the Written Optical State in Electrochromic DNA Liquid Crystals[J]. Nat Commun, 2016,711476. doi: 10.1038/ncomms11476
21. [21]
  Candeias L P, Steenken S. Structure and Acid-Base Properties of One-Electron-Oxidized Deoxyguanosine, Guanosine, and 1-Methylguanosine[J]. J Am Chem Soc, 1989,20(20):1094-1099.
22. [22]
  Rokhlenko Y, Cadet J, Geacintov N E. Mechanistic Aspects of Hydration of Guanine Radical Cations in DNA[J]. J Am Chem Soc, 2014,136(16):5956-5962. doi: 10.1021/ja412471u
23. [23]
  XIA Xulin, YAN Liangfa, GU Xupeng. Synthesis, Characterization and Properties of Novel Azobenzene Containing Metal Complexes[J]. Chinese J Appl Chem, 2010,27(1):32-37.
24. [24]
  GUAN Xiaolin, ZHANG Yang, FAN Hongting. Synthesis and Photoelectric Properties of Novel Liquid Crystalline Compound Bearing Diethynyl and Naphthyl Groups with High Birefringence[J]. Chinese J Appl Chem, 2016,33(5):533-541. doi: 10.11944/j.issn.1000-0518.2016.05.150198
25. [25]
  Perriman A W, Cölfen H, Hughes R W. Solvent-Free Protein Liquids and Liquid Crystals[J]. Angew Chem Int Ed, 2009,48(34):6242-6246. doi: 10.1002/anie.200903100
26. [26]
  TANG Longxiang, YAN Manqing, LIU Chunhua. Crystallization Behavior of UV-Photocrosslinked High-Density Polyethylene[J]. Chinese J Appl Chem, 2009,26(9):1019-1022.
27. [27]
  Sharma K P, Zhang Y, Thomas M R. Self-Organization of Glucose Oxidase-Polymer Surfactant Nanoconstructs in Solvent-Free Soft Solids and Liquids[J]. J Phys Chem B, 2014,118(39):11573-11580. doi: 10.1021/jp507566u
28. [28]
  Hanski S, Junnila S, Almásy L. Structural and Conformational Transformations in Self-Assembled Polypeptide-Surfactant Complexes[J]. Macromolecules, 2008,41(3):866-872. doi: 10.1021/ma7019495
29. [29]
  Kolbe A, del Mercato L L, Abbasi A Z. De Novo Design of Supercharged, Unfolded Protein Polymers, and Their Assembly into Supramolecular Aggregates[J]. Macromol Rapid Commun, 2011,32(2):186-190. doi: 10.1002/marc.v32.2
30. [30]
  ZHU Xin, ZHANG Shuyuan, LI Hui. Liquid Crystalline Behavior of Schiff-Base Type Liquid Crystalline Crown ether Potassium Complexes Containing Dibenzo-18-crown-6 Unit[J]. Chinese J Appl Chem, 2010,27(1):38-42.
1. [1]
  Yukai Jiang , Yihan Wang , Yunkai Zhang , Yunping Wei , Ying Ma , Na Du . Characterization and Phase Diagram of Surfactant Lyotropic Liquid Crystal. University Chemistry, 2024, 39(4): 114-118. doi: 10.3866/PKU.DXHX202309033
2. [2]
  Congying Lu , Fei Zhong , Zhenyu Yuan , Shuaibing Li , Jiayao Li , Jiewen Liu , Xianyang Hu , Liqun Sun , Rui Li , Meijuan Hu . Experimental Improvement of Surfactant Interface Chemistry: An Integrated Design for the Fusion of Experiment and Simulation. University Chemistry, 2024, 39(3): 283-293. doi: 10.3866/PKU.DXHX202308097
3. [3]
  Yongmin Zhang , Shuang Guo , Mingyue Zhu , Menghui Liu , Sinong Li . Design and Improvement of Physicochemical Experiments Based on Problem-Oriented Learning: a Case Study of Liquid Surface Tension Measurement. University Chemistry, 2024, 39(2): 21-27. doi: 10.3866/PKU.DXHX202307026
4. [4]
  Zhenhua Wang , Haoyang Feng , Xiaoyang Shao , Wenru Fan . Vitamins in Solid Propellants: Controlled Synthesis of Neutral Macromolecular Bonding Agents. University Chemistry, 2025, 40(4): 1-9. doi: 10.3866/PKU.DXHX202401007
5. [5]
  Shuang Meng , Haixin Long , Zhou Zhou , Meizhu Rong . Inorganic Chemistry Curriculum Design and Implementation of Based on “Stepped-Task Driven + Multi-Dimensional Output” Model: A Case Study on Intermolecular Forces. University Chemistry, 2024, 39(3): 122-131. doi: 10.3866/PKU.DXHX202309008
6. [6]
  Haitang WANG , Yanni LING , Xiaqing MA , Yuxin CHEN , Rui ZHANG , Keyi WANG , Ying ZHANG , Wenmin WANG . Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1474-1482. doi: 10.11862/CJIC.20240188
7. [7]
  Dan Li , Hui Xin , Xiaofeng Yi . Comprehensive Experimental Design on Ni-based Catalyst for Biofuel Production. University Chemistry, 2024, 39(8): 204-211. doi: 10.3866/PKU.DXHX202312046
8. [8]
  Jiaxun Wu , Mingde Li , Li Dang . The R eaction of Metal Selenium Complexes with Olefins as a Tutorial Case Study for Analyzing Molecular Orbital Interaction Modes. University Chemistry, 2025, 40(3): 108-115. doi: 10.12461/PKU.DXHX202405098
9. [9]
  Changqing MIAO , Fengjiao CHEN , Wenyu LI , Shujie WEI , Yuqing YAO , Keyi WANG , Ni WANG , Xiaoyan XIN , Ming FANG . Crystal structures, DNA action, and antibacterial activities of three tetranuclear lanthanide-based complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2455-2465. doi: 10.11862/CJIC.20240192
10. [10]
  Yuhui Yang , Jintian Luo , Biao Zuo . A Teaching Approach to Polymer Surface and Interface in Undergraduate Polymer Physics Courses. University Chemistry, 2025, 40(4): 126-130. doi: 10.12461/PKU.DXHX202408056
11. [11]
  Xin MA , Ya SUN , Na SUN , Qian KANG , Jiajia ZHANG , Ruitao ZHU , Xiaoli GAO . A Tb₂ complex based on polydentate Schiff base: Crystal structure, fluorescence properties, and biological activity. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1347-1356. doi: 10.11862/CJIC.20230357
12. [12]
  Xinyu ZENG , Guhua TANG , Jianming OUYANG . Inhibitory effect of Desmodium styracifolium polysaccharides with different content of carboxyl groups on the growth, aggregation and cell adhesion of calcium oxalate crystals. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1563-1576. doi: 10.11862/CJIC.20230374
13. [13]
  Zhuo WANG , Junshan ZHANG , Shaoyan YANG , Lingyan ZHOU , Yedi LI , Yuanpei LAN . Preparation and photocatalytic performance of CeO₂-reduced graphene oxide by thermal decomposition. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1708-1718. doi: 10.11862/CJIC.20240067
14. [14]
  Xiyuan Su , Zhenlin Hu , Ye Fan , Xianyuan Liu , Xianyong Lu . Change as You Want: Multi-Responsive Superhydrophobic Intelligent Actuation Material. University Chemistry, 2024, 39(5): 228-237. doi: 10.3866/PKU.DXHX202311059
15. [15]
  Tianyun Chen , Ruilin Xiao , Xinsheng Gu , Yunyi Shao , Qiujun Lu . Synthesis, Crystal Structure, and Mechanoluminescence Properties of Lanthanide-Based Organometallic Complexes. University Chemistry, 2024, 39(5): 363-370. doi: 10.3866/PKU.DXHX202312017
16. [16]
  Yang Lv , Yingping Jia , Yanhua Li , Hexiang Zhong , Xinping Wang . Integrating the Ideological Elements with the “Chemical Reaction Heat” Teaching. University Chemistry, 2024, 39(11): 44-51. doi: 10.12461/PKU.DXHX202402059
17. [17]
  Xinting XIONG , Zhiqiang XIONG , Panlei XIAO , Xuliang NIE , Xiuying SONG , Xiuguang YI . Synthesis, crystal structures, Hirshfeld surface analysis, and antifungal activity of two complexes Na(Ⅰ)/Cd(Ⅱ) assembled by 5-bromo-2-hydroxybenzoic acid ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1661-1670. doi: 10.11862/CJIC.20240145
18. [18]
  Hailian Tang , Siyuan Chen , Qiaoyun Liu , Guoyi Bai , Botao Qiao , Fei Liu . Stabilized Rh/hydroxyapatite Catalyst for Furfuryl Alcohol Hydrogenation: Application of Oxidative Strong Metal-Support Interactions in Reducing Conditions. Acta Physico-Chimica Sinica, 2025, 41(4): 100036-. doi: 10.3866/PKU.WHXB202408004
19. [19]
  Limei CHEN , Mengfei ZHAO , Lin CHEN , Ding LI , Wei LI , Weiye HAN , Hongbin WANG . Preparation and performance of paraffin/alkali modified diatomite/expanded graphite composite phase change thermal storage material. Chinese Journal of Inorganic Chemistry, 2024, 40(3): 533-543. doi: 10.11862/CJIC.20230312
20. [20]
  Mingxin LU , Liyang ZHOU , Xiaoyu XU , Xiaoying FENG , Hui WANG , Bin YAN , Jie XU , Chao CHEN , Hui MEI , Feng GAO . Preparation of La-doped lead-based piezoelectric ceramics with both high electrical strain and Curie temperature. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 329-338. doi: 10.11862/CJIC.20240206

Get Citation

PDF

XML

Metrics

PDF Downloads(8)
Abstract views(1355)
HTML views(162)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142