Citation: ZHOU Feng, LIU Shu, LIU Zhiqiang, SONG Fengrui. Application of Methanol and Ethanol in Argon-Direct Real Time Mass Spectrometry Analysis[J]. Chinese Journal of Applied Chemistry, ;2017, 34(6): 729-732. doi: 10.11944/j.issn.1000-0518.2017.06.160392 shu

Application of Methanol and Ethanol in Argon-Direct Real Time Mass Spectrometry Analysis

ZHOU Feng ^a,b ,
LIU Shu ^a ,
LIU Zhiqiang ^a ,
SONG Fengrui ^a,*,,

a.
National Center of Mass Spectrometry in Changchun, Jilin Province Key Laboratory of Chinese Medicine Chemistry and Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
b.
University of the Chinese Academy of Sciences, Beijing 100039, China

Corresponding author: SONG Fengrui, songfr@ciac.ac.cn
Received Date: 28 September 2016
Revised Date: 15 December 2016
Accepted Date: 17 January 2017

Fund Project: the National Natural Science Foundation of China 81373952the National Natural Science Foundation of China 21673219

Figures(3)

In this research, argon was used as the running gas in direct analysis in real time mass spectrometry instead of helium in order to reduce the cost of experiment. Methanol and alcohol as reactive reagents improve the ionization efficiency of analytes and expand the application of Ar-DART-MS. This is because the above reagents play important roles as the medium of the energy transferring and the domor of proton in Ar-DART-MS analysis. Through the analysis of background signal from methol and alcohol as reactive reagents in Ar-DART-MS and their affect on sample ionization, the application scope of methanol and alcohol as reactive reagents in Ar-DART-MS was discussed. Some possible characteristic reactions were also explored. The validity of this method was verified by the analysis of reserpine.
- direct analysis in real time mass spectrometry,
- argon,
- methanol,
- alcohol
1. [1]
  Cody R B, Larame'e J A, Durst H D. Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions[J]. Anal Chem, 2005,77(8):2297-2302. doi: 10.1021/ac050162j
2. [2]
  Takats Z, Wiseman J M, Gologan B. Mass Spectrometry Sampling under Ambient Conditions with Desorption Electrospray Ionization[J]. Science, 2004,306(5695):471-474. doi: 10.1126/science.1104404
3. [3]
  Song L G, Gibson S C, Bhandari D. Ionization Mechanism of Positive-Ion Direct Analysis in Real Time:A Transient Microenvironment Concept[J]. Anal Chem, 2009,81(24):10080-10088. doi: 10.1021/ac901122b
4. [4]
  Gross J H. Direct Analysis in Real Time-A Critical Review on DART-MS[J]. Anal Bioanal Chem, 2014,406(1):63-80. doi: 10.1007/s00216-013-7316-0
5. [5]
  Harris G A, Falcone C E, Fernández F M. Sensitivity "Hot Spots" in the Direct Analysis in Real Time Mass Spectrometry of Nerve Agent Simulants[J]. J Am Soc Mass Spectrom, 2012,23(1):153-161. doi: 10.1007/s13361-011-0276-8
6. [6]
  CHEN Huanwen, HU Bin, ZHANG Xie. Fundamental Principles, Practical Applications of Ambient Ionization Mass Spectrometry for Direct Analysis of Complex Samples[J]. Chinese J Anal Chem, 2010,38(8):1069-1088.
7. [7]
  ZHANG Jialing, HUO Feifeng, ZHOU Zhigui. The Principles and Application of an Ambient Ionization Method-Direct Analysis in Real Time(DART)[J]. Prog Chem, 2012,24(1):101-109.
8. [8]
  Dane A J, Cody O B. Selective Ionization of Melamine in Powdered Milk by Using Argon Direct Analysis in Real Time(DART) Mass Spectrometry[J]. Analyst, 2010,135:696-699. doi: 10.1039/b923561b
9. [9]
  Ding X L, Zhan X F, Yuan X. Microfabricated Glow Discharge Plasma(MFGDP) for Ambient Desorption/Ionization Mass Spectrometry[J]. Anal Chem, 2013,85(19):9013-9020. doi: 10.1021/ac401359k
10. [10]
  Abedi A, Sattar L, Gharibi M. Investigation of Temperature, Electric Field and Drift-Gas Composition Effects on the Mobility of NH₄⁺ Ions in He, Ar, N₂, and CO₂[J]. Int J Mass Spectrom, 2014,370:101-106. doi: 10.1016/j.ijms.2014.06.014
11. [11]
  Cody R B. Observation of Molecular Ions and Analysis of Nonpolar Compounds with the Direct Analysis in Real Time Ion Source[J]. Anal Chem, 2009,81(3):1101-1107. doi: 10.1021/ac8022108
12. [12]
  Kratzer J, Mester Z, Sturgeon R E. Comparison of Dielectric Barrier Discharge, Atmospheric Pressure Radiofrequency-driven Glow Discharge and Direct Analysis in Real Time Sources for Ambient Mass Spectrometry of Acetaminophen[J]. Spectrochim Acta Part B, 2011,66(8):594-603. doi: 10.1016/j.sab.2011.06.005
13. [13]
  DAI Chunmei, WANG Jiabo, KONG Weijun. Investigation on the Antibacterial Activity of Coptischinensis Franch and Its Components Compatibility by Microcalorimetry[J]. Acta Chim Sin, 2010,68(10):936-940.
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