Citation: ZHOU Shuo, TANG Peng, WANG Yun-Jiao, WANG Liang, WANG De-Qiang. Applications of Nanopore Sensing in Detection of Toxic Molecules[J]. Chinese Journal of Analytical Chemistry, ;2018, 46(6): 826-835. doi: 10.11895/j.issn.0253-3820.181200 shu

Applications of Nanopore Sensing in Detection of Toxic Molecules

Research Center for Precision Medicine & Single-Molecule Diagnostics, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China

Received Date: 26 March 2018
Revised Date: 8 May 2018

Fund Project: This work was supported by the West Light Foundation of Chinese Academy of Sciences (CAS), the CAS Pioneer Hundred Talents Program, the National Natural Science Foundation of China (No. 51503206) and the Entrepreneurship and Innovation Support Program for Returned Oversea Students of Chongqing, China (No.cx2017097).

As a novel analytical method, nanopore sensing is widely applied in many fields such as nucleic acids sequencing, protein/peptide analysis, detection of metal ions and biomacromolecules including virus, bacteria, etc. With the growing public concerns over dietary safety and public security, there has been a greater demand on the detection of toxic molecules. With its high sensitivity and selectivity, nanopore sensing is considered as a more powerful assay, which has been reported in many research articles. Accordingly, this paper surveys the application studies of nanopore sensing in detection of toxic molecules.
- Nanopore technology,
- Single-molecule sensing,
- Toxic molecules,
- Sensitivity,
- Selectivity,
- Review
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