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Citation: ZHAO Jia-Hui, FENG Jing-Lan, XI Nan-Nan, SUN Jian-Hui. Determination of Paraben and Its Metabolite in Sediments by Ultra Performance Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry[J]. Chinese Journal of Analytical Chemistry, ;2018, 46(2): 260-264. doi: 10.11895/j.issn.0253-3820.170330 shu

Determination of Paraben and Its Metabolite in Sediments by Ultra Performance Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

College of Chemistry and Environmental Sciences, Henan Normal University, Henan Key Laboratory for Environmental Pollution Control, Xinxiang 453007, China

Received Date: 25 May 2017
Revised Date: 10 October 2017

A new method for simultaneous determination of six benzoic acid esters and their metabolite p-hydroxybenzoic acid (p-HB) in sediments was developed. The samples were extracted with methanol and water, and then the extraction was purified by Oasis MCX solid phase column. The separation of targets was conducted by passing through a UPLC^® HSS T3 column with a methanol-0.1% acid aqueous solution as the mobile phase under gradient elution. The qualitative analysis of the analytes was measured by Ultra performance liquid chromatography-Triple quadrupole tandem mass under multiple reaction monitoring mode (MRM) and the internal standard method was applied for quantitative analysis. The results indicated that seven target substances had a good linear relationship in the range of 0.1-500 μg/L with correlation coefficients above 0.9995 and the detection limits of 0.75-1.23 ng/g. The recoveries ranged from 65.5% to 88.3% and the relative standard deviation was 7.4%-13.6%. This method was suitable for the measurement of benzoic acid esters with the advantages such as simple processing, good selectivity and high sensitivity.
- Ultra performance liquid chromatography-triple quadrupole tandem mass spectrometry,
- Benzoic acid esters,
- Sediment
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
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Determination of Paraben and Its Metabolite in Sediments by Ultra Performance Liquid Chromatography-Triple Quadrupole Tandem Mass Spectrometry

南开大学师唯/华北电力大学（保定）刘景维：二维配位聚合物中有序的亲锂冠醚位点用于无枝晶锂沉积

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通讯作者: 陈斌, bchen63@163.com