Citation: ZHUANG Qi-Chen, NING Rui-Zhi, MA Yuan, LIN Jin-Ming. Recent Development in Microfluidic Chips for in vitro Cell-based Research[J]. Chinese Journal of Analytical Chemistry, ;2016, 44(4): 522-532. doi: 10.11895/j.issn.0253-3820.160003 shu

Recent Development in Microfluidic Chips for in vitro Cell-based Research

1.
¹ Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China;
2.
² Department of Biomaterial Sciences, The University of Tokyo, Tokyo 113-8657, Japan

Corresponding author: LIN Jin-Ming,
Received Date: 3 January 2016
Available Online: 16 January 2016
Fund Project: 本文系国家自然科学基金(Nos.81373373,21227006,21435002) (Nos.81373373,21227006,21435002)国家"211工程"项目"高等学校仪器设备和优质资源共享系统"(No.CERS-1-75)资助 (No.CERS-1-75)

Microfluidic technology has become a powerful tool in cell-based research due to its inherent advantages. The research progress of cell culture on chips, simulation and manipulation of cell microenvironment on chips, single cell analysis on chips, organ-on-a-chip, and chip-mass spectrometry technology was introduced in this review. Morover, the summary and prospect on the microfluidic technology were introduced to give some insights for researchers who were interested in developing microfluidic platforms for cell-based research.
- Microfluidic chip,
- Cell culture,
- Microenvironment,
- Single cell,
- Organ-on-a-chip,
- Chip-mass spectrometry,
- Cell analysis,
- Review
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