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Citation: Shiyi WANG, Chaolong CHEN, Xiangjian KONG, Lansun ZHENG, Lasheng LONG. Polynuclear lanthanide compound [Ce4ⅢCe6Ⅳ(μ3-O)4(μ4-O)4(acac)14(CH3O)6]·2CH3OH for the hydroboration of amides to amine[J]. Chinese Journal of Inorganic Chemistry, ;2025, 41(1): 88-96. doi: 10.11862/CJIC.20240342 shu

Polynuclear lanthanide compound [Ce4ⅢCe6Ⅳ(μ3-O)4(μ4-O)4(acac)14(CH3O)6]·2CH3OH for the hydroboration of amides to amine

  • State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005, China

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  • In this study, we utilized a polynuclear lanthanide complex [Ce4ⅢCe6Ⅳ(μ3-O)4(μ4-O)4(acac)14(CH3O)6]·2CH3OH (Ce10) constructed with acetylacetone (Hacac) as a Lewis acid catalyst to achieve an efficient borohydride reduction of amides, with yields ranging from 50% to 99%. Additionally, this method was successfully applied for the gram-scale synthesis of the antidepressant drug phenylethylamine. The catalytic mechanism was investigated using NMR and single-crystal X-ray diffraction analysis.
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