Citation: Qi XIAO, Guang-Xian LIU, Jian-Dan CHEN, Zheng-Zhi YIN, Chun-Chuan GU, Hong-Ying LIU. Non-enzyme Glucose Biosensor Based on Bimetallic Pt-Au Nanoparticles Decorated Acupuncture Needle[J]. Chinese Journal of Inorganic Chemistry, ;2022, 38(6): 1159-1170. doi: 10.11862/CJIC.2022.119 shu

Non-enzyme Glucose Biosensor Based on Bimetallic Pt-Au Nanoparticles Decorated Acupuncture Needle

Qi XIAO ^{1, #} ,
Guang-Xian LIU ^{1, #} ,
Jian-Dan CHEN ¹ ,
Zheng-Zhi YIN ^2,, ,
Chun-Chuan GU ³ ,
Hong-Ying LIU ^1,,

1.
College of Automation, Hangzhou Dianzi University, Hangzhou 310018, China
2.
College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing, Zhejiang 314001, China
3.
Hangzhou Cancer Hospital, Hangzhou 310002, China

Corresponding author: Zheng-Zhi YIN, yinzhengzhi@mail.zjxu.edu.cn Hong-Ying LIU, liuhongying@hdu.edu.cn
Received Date: 18 December 2021
Revised Date: 22 April 2022

Figures(9)

An electrochemical biosensor for non-enzyme glucose detection was constructed based on the synergistic action of gold (Au) nanoparticles and platinum (Pt) nanoparticles on the surface of a stainless steel acupuncture needle (AN), which was achieved by respectively electrodepositing. The functional interface (Pt/Au/AN) was characterized by a scanning electron microscope, showing that cabbage-like nanomaterials were uniformly and densely distributed on the surface of AN. Pt/Au/AN electrode also possessed outstanding electrochemical characteristics, which were studied by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Significantly, Pt/Au/AN electrode exhibited remarkably electrocatalytic activity toward glucose oxidation compared with Au/AN or Pt/AN electrode. The results indicated that the contact interface of bimetallic Pt/Au was the vital electrocatalytic site for glucose oxidation. A further study proved that the contact interface exhibited intrinsic features and distinct selectivity for sensing glucose. The prepared sensor showed a wide linear range from 0.1 to 35 mmol·L^-1, and the detection limit of glucose was 0.076 3 mmol·L^-1. The sensor showed great stability, excellent selectivity, and miniaturization. Furthermore, the sensor was successfully used for the detection of glucose in human serum.
- acupuncture needle,
- contact interface of bimetallic Pt/Au,
- non-enzyme sensor,
- glucose
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