Citation: WU Da-Ling, ZHANG Min-Zhi, WU Xiao-Yong, ZHAO Guo-Liang. Syntheses, Crystal Structures and DNA-Binding of Two Zinc(Ⅱ) Complexes Constructed by 4-Methyl-1, 2, 3-thiadiazol-5-carboxylic Acid[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(5): 973-980. doi: 10.11862/CJIC.2018.107 shu

Syntheses, Crystal Structures and DNA-Binding of Two Zinc(Ⅱ) Complexes Constructed by 4-Methyl-1, 2, 3-thiadiazol-5-carboxylic Acid

1.
College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, Zhejiang 321004, China
2.
Xingzhi College, Zhejiang Normal University, Jinhua, Zhejiang 321004, China

Corresponding author: ZHAO Guo-Liang, sky53@zjnu.cn
Received Date: 20 November 2017
Revised Date: 11 January 2018

Figures(9)

Two new zinc complexes[Zn(MTC)₂(bpp)]_n (1) and[Zn(MTC)(phen)(H₂O)₂](MTC) (2) (HMTC=4-methyl-1, 2, 3-thiadiazol-5-carboxylic, C₄H₄N₂O₂S; bpp=1, 3-bis(4-pyridyl) propane; phen=1-10-phenanthroline) have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis, IR spectra, PXRD and TG. The single crystal X-ray diffraction reveals that the complex 1 is two-dimensional network structure and crystallized in monoclinic with space group P2₁/c. Central Zn²⁺ is four-coordinated forming a distorted tetrahedron coordina-tion geometry. The complex 2 is two-dimensional layered structure and crystallized in triclinic with space group P1. Central Zn²⁺ is five-coordinated forming a distorted trigonal bipyramid coordination geometry. In addition, the interaction of complexes and ligand with EB-DNA were also studied by EtBr fluorescence probe. The interaction of complexes with DNA is stronger than ligand.
- 4-methyl-1, 2, 3-thiadiazol-5-carboxylic acid,
- zinc complex,
- crystal structure,
- DNA-binding
1. [1]
  Wang H L, Zhang D P, Sun D F, et al. CrystEngComm, 2010, 12:1096-1102 doi: 10.1039/B917659D
2. [2]
  Feng X, Ma L F, Liu L, et al. Cryst. Growth Des., 2013, 13(10):4469-4479 doi: 10.1021/cg4009587
3. [3]
  Sakamoto R, Iwashima T, Kogel J F, et al. J. Am. Chem. Soc., 2016, 138(17):5666-5677 doi: 10.1021/jacs.6b02128
4. [4]
  Medishetty R, Nalla V, Nemec L, et al. Adv. Mater., 2017, 29(17):1605637 doi: 10.1002/adma.v29.17
5. [5]
  Zhao J, Wang X L, Shi X, et al. Inorg. Chem., 2011, 50(8):3198-3205 doi: 10.1021/ic101112b
6. [6]
  Shi Z Z, Pan Z R, Jia H L, et al. Cryst. Growth Des., 2016, 16(5):2747-2755 doi: 10.1021/acs.cgd.6b00056
7. [7]
  Hwang I H, Jo Y D, Kim H Y, et al. Polyhedron, 2012, 42(1):282-290 doi: 10.1016/j.poly.2012.05.040
8. [8]
  Li Q Y, Chen D Y, He M H, et al. J. Solid State Chem., 2012, 190:196-201 doi: 10.1016/j.jssc.2012.02.007
9. [9]
  Okamoto K, Matsumoto K, Hille R, et al. Biochemsitry, 2004, 101(21):7931-7936
10. [10]
  Pinto L D, Puppin P A L, Behring V M, et al. Inorg Chim. Acta, 2010, 363(10):2624-2630
11. [11]
  Beckmann J, Dakternieks D, Duthie A, et al. J. Organomet. Chem., 2003, 688(1/2):56-61
12. [12]
  Chen B L, Ockwig N W, Contreras D S, et al. Angew. Chem. Int. Ed., 2005, 117(30):4823-4827 doi: 10.1002/(ISSN)1521-3757
13. [13]
  Kumar K V, Preuss K, Titirici M M, et al. Chem. Rev., 2017, 117(3)1796-1825 doi: 10.1021/acs.chemrev.6b00505
14. [14]
  Lin J Y S. Science, 2016, 353(6295):121-122 doi: 10.1126/science.aag2267
15. [15]
  Rodenas T, Luz I, Prieto G, et al. Nat. Mater., 2015, 14:48-55 doi: 10.1038/nmat4113
16. [16]
  Semerci F, Yesilel O Z, Soylu M S, et al. Polyhedron, 2013, 50(1):314-320 doi: 10.1016/j.poly.2012.10.009
17. [17]
  Ma Z B, Moulton B. Coord. Chem. Rev., 2011, 255(15/16):1623-1641
18. [18]
  Efthimiadou E K, Karaliota A, Psomas G. J. Inorg. Biochem., 2010, 104(4):455-466 doi: 10.1016/j.jinorgbio.2009.12.019
19. [19]
  Rosi N L, Kim J, Eddaoudi M, et al. J. Am. Chem. Soc., 2005, 127(5):1504-1518 doi: 10.1021/ja045123o
20. [20]
  HU De-Yu, SONG Bao-An, HE Wei, et al. Chinese Journal of Synthetic Chemistry, 2006, 14(4):319-328
21. [21]
  Cui Y J, Qian G, Chen L, et al. Dyes Pigm., 2008, 77(1):217-222 doi: 10.1016/j.dyepig.2007.05.005
22. [22]
  Yamamoto T, Otsuka S I, Fukumoto H, et al. J. Polym. Sci. Part A:Polym. Chem., 2011, 49(6):1508-1512 doi: 10.1002/pola.24557
23. [23]
  Osaka I, Zhang R, Liu J Y, et al. Chem. Mater., 2010, 22(14):4191-4196 doi: 10.1021/cm101052b
24. [24]
  Lyu F J, Zhang Y F, Zare R N, et al. Nano Lett., 2014, 14(10):5761-5765 doi: 10.1021/nl5026419
25. [25]
  Yang J, Chen X J, Li Y S, et al. Chem. Mater., 2017, 29(10):4580-4589 doi: 10.1021/acs.chemmater.7b01329
26. [26]
  CHEN Qing, LU Li-Ping. Chinese J. Inorg. Chem., 2016, 32(6):1001-1008 doi: 10.11862/CJIC.2016.123
27. [27]
  ZHU Xing-Cheng, HUANG Chao, ZHANG Qi-Long, et al. Chinese J. Inorg. Chem., 2016, 32(6)1041-1046 doi: 10.11862/CJIC.2016.128
28. [28]
  Sheldrick G M. SADABS: Program for Empirical Absorption Correction of Area Detector Data, University of Göttingen, Germany, 1996.
29. [29]
  Sheldrick G M. SHELXS-97, Program for the Solution of Crystal Structure, University of Göttingen, Germany, 1997.
30. [30]
  Sheldrick G M. SHELXL-97, Program for the Refinement of Crystal Structure, University of Göttingen, Germany, 1997.
31. [31]
  Li X M, Dong Y H, Wang Q W, et al. Acta Crystallogr. Sect. E:Struct. Rep. Online, 2007, 63:1274-1276
32. [32]
  Lin X F. Acta Crystallogr. Sect. E:Struct. Rep. Online, 2006, 62:2039-2040 doi: 10.1107/S1600536806029928
33. [33]
  GUO Hang-Min, ZHAO Guo-Liang, WU Xiao-Yong, et al. Chinese J. Inorg. Chem., 2011, 27(5):855-859
34. [34]
  Lakowicz J R, Webber G. Biochemistry, 1973, 12(21):4161-4170 doi: 10.1021/bi00745a020
1. [1]
  Lu LIU , Huijie WANG , Haitong WANG , Ying LI . Crystal structure of a two-dimensional Cd(Ⅱ) complex and its fluorescence recognition of p-nitrophenol, tetracycline, 2, 6-dichloro-4-nitroaniline. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1180-1188. doi: 10.11862/CJIC.20230489
2. [2]
  Chao LIU , Jiang WU , Zhaolei JIN . Synthesis, crystal structures, and antibacterial activities of two zinc(Ⅱ) complexes bearing 5-phenyl-1H-pyrazole group. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 1986-1994. doi: 10.11862/CJIC.20240153
3. [3]
  Yao HUANG , Yingshu WU , Zhichun BAO , Yue HUANG , Shangfeng TANG , Ruixue LIU , Yancheng LIU , Hong LIANG . Copper complexes of anthrahydrazone bearing pyridyl side chain: Synthesis, crystal structure, anticancer activity, and DNA binding. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 213-224. doi: 10.11862/CJIC.20240359
4. [4]
  Yingyue ZHANG , Liuqing KANG , Yating YANG , Xiaofen GUAN , Wenmin WANG . Crystal structure and antibacterial activity of two Gd₂ complexes based on polydentate Schiff-base ligands. Chinese Journal of Inorganic Chemistry, 2025, 41(9): 1867-1877. doi: 10.11862/CJIC.20250100
5. [5]
  Jiarong ZHU , Xiaohua ZHANG , Xinting XIONG , Xuliang NIE , Xiuying SONG , Miaomiao ZHANG , Dayong PENG , Xiuguang YI . Crystal structure, Hirshfeld surface analysis, and antifungal activity of five complexes based on 2,5-bis(carboxymethoxy)terephthalic acid. Chinese Journal of Inorganic Chemistry, 2025, 41(11): 2358-2370. doi: 10.11862/CJIC.20250150
6. [6]
  Lulu DONG , Jie LIU , Hua YANG , Yupei FU , Hongli LIU , Xiaoli CHEN , Huali CUI , Lin LIU , Jijiang WANG . Synthesis, crystal structure, and fluorescence properties of Cd-based complex with pcu topology. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 809-820. doi: 10.11862/CJIC.20240171
7. [7]
  Xiaoling WANG , Hongwu ZHANG , Daofu LIU . Synthesis, structure, and magnetic property of a cobalt(Ⅱ) complex based on pyridyl-substituted imino nitroxide radical. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 407-412. doi: 10.11862/CJIC.20240214
8. [8]
  Kaimin WANG , Xiong GU , Na DENG , Hongmei YU , Yanqin YE , Yulu MA . Synthesis, structure, fluorescence properties, and Hirshfeld surface analysis of three Zn(Ⅱ)/Cu(Ⅱ) complexes based on 5-(dimethylamino) isophthalic acid. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1397-1408. doi: 10.11862/CJIC.20240009
9. [9]
  Yinling HOU , Jia JI , Hong YU , Xiaoyun BIAN , Xiaofen GUAN , Jing QIU , Shuyi REN , Ming FANG . A rhombic Dy₄-based complex showing remarkable single-molecule magnet behavior. Chinese Journal of Inorganic Chemistry, 2025, 41(3): 605-612. doi: 10.11862/CJIC.20240251
10. [10]
  Meirong HAN , Xiaoyang WEI , Sisi FENG , Yuting BAI . A zinc-based metal-organic framework for fluorescence detection of trace Cu²⁺. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1603-1614. doi: 10.11862/CJIC.20240150
11. [11]
  Zihe SONG , Jinjin ZHAO , Ning REN , Jianjun ZHANG . Crystal structure, thermal analysis, and luminescence properties of six heterocyclic lanthanide complexes. Chinese Journal of Inorganic Chemistry, 2026, 42(1): 181-192. doi: 10.11862/CJIC.20250126
12. [12]
  Jia JI , Zhaoyang GUO , Wenni LEI , Jiawei ZHENG , Haorong QIN , Jiahong YAN , Yinling HOU , Xiaoyan XIN , Wenmin WANG . Two dinuclear Gd(Ⅲ)-based complexes constructed by a multidentate diacylhydrazone ligand: Crystal structure, magnetocaloric effect, and biological activity. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 761-772. doi: 10.11862/CJIC.20240344
13. [13]
  Hongren RONG , Gexiang GAO , Zhiwei LIU , Ke ZHOU , Lixin SU , Hao HUANG , Wenlong LIU , Qi LIU . High-performance supercapacitor based on 1D cobalt-based coordination polymer. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1183-1195. doi: 10.11862/CJIC.20250034
14. [14]
  Ruiyan CHEN , Yanping HE , Jian ZHANG . Synthesis and third-order nonlinear optical property of Ti₄L₆ cage-based metal-organic framework. Chinese Journal of Inorganic Chemistry, 2025, 41(10): 2149-2156. doi: 10.11862/CJIC.20250177
15. [15]
  Yuxin CHEN , Yanni LING , Yuqing YAO , Keyi WANG , Linna LI , Xin ZHANG , Qin WANG , Hongdao LI , Wenmin WANG . Construction, structures, and interaction with DNA of two Sm^Ⅲ₄ complexes. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1141-1150. doi: 10.11862/CJIC.20240258
16. [16]
  Xiumei LI , Yanju HUANG , Bo LIU , Yaru PAN . Syntheses, crystal structures, and quantum chemistry calculation of two Ni(Ⅱ) coordination polymers. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 2031-2039. doi: 10.11862/CJIC.20240109
17. [17]
  Xiumei LI , Linlin LI , Bo LIU , Yaru PAN . Syntheses, crystal structures, and characterizations of two cadmium(Ⅱ) coordination polymers. Chinese Journal of Inorganic Chemistry, 2025, 41(3): 613-623. doi: 10.11862/CJIC.20240273
18. [18]
  Yukun CHEN , Kexin FENG , Bolun ZHANG , Wentao SONG , Jianjun ZHANG . Syntheses, crystal structures, and diametrically opposed mechanically-stimulated luminescence response of two Mg(Ⅱ) metal-organic frameworks. Chinese Journal of Inorganic Chemistry, 2025, 41(6): 1227-1234. doi: 10.11862/CJIC.20240448
19. [19]
  Yinxia SUN , Liping LIU , Xue BAI , Yu SUN , Wanhong SUN , Zhepeng DENG , Jianghai CHEN , Jianjun WANG , Li XU , Shuzhen ZHANG . Synthesis and crystal structures of Co(Ⅱ)/Cu(Ⅱ) coordination polymers based on solvent and ligand concentration regulation strategy. Chinese Journal of Inorganic Chemistry, 2026, 42(2): 340-354. doi: 10.11862/CJIC.20250226
20. [20]
  Xiaoxia WANG , Ya'nan GUO , Feng SU , Chun HAN , Long SUN . Synthesis, structure, and electrocatalytic oxygen reduction reaction properties of metal antimony-based chalcogenide clusters. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1201-1208. doi: 10.11862/CJIC.20230478

Get Citation

PDF

XML

Metrics

PDF Downloads(3)
Abstract views(1134)
HTML views(85)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142