Citation: FENG Yong-Lan, KUANG Dai-Zhi, ZHANG Fu-Xing, YU Jiang-Xi, JIANG Wu-Jiu, ZHU Xiao-Ming. Microwave-Solvothermal Syntheses, Crystal Structures and in Vitro Antitumor Activities of Two Bis[oxo-bis (aromatic carboxylato dibutyltin)][J]. Chinese Journal of Inorganic Chemistry, ;2017, 33(4): 589-594. doi: 10.11862/CJIC.2017.071 shu

Microwave-Solvothermal Syntheses, Crystal Structures and in Vitro Antitumor Activities of Two Bis[oxo-bis (aromatic carboxylato dibutyltin)]

Key Laboratory of Functional Organometallic Materials of Hengyang Normal University, Colleges of Hunan Province, College of Chemistry and Material Science, Hengyang Normal University, Hengyang, Hunan 421008, China

Corresponding author: KUANG Dai-Zhi, hnkcq@qq.com
Received Date: 25 September 2016
Revised Date: 7 January 2017

Figures(3)

Two di-n-butyltin compounds with μ₃-O bridging the framework, [(μ₃-O)(n-Bu₂Sn)₂(O₂CR)₂]₂(R=4-(t-Bu)-C₆H₅ (1), (3-Me-4-NH₂)-C₆H₄ (2)), were obtained by microwave-assisted solvothermal reaction of di-n-butyltin oxide precursor with the aromatic acid in methanol environments, which have been structurally characterized by elemental analysis, IR and NMR (¹H, ¹³C and ¹¹⁹Sn) spectra and X-ray crystallography diffraction analyses. This compound was of a centrosymmetric dimer structure mode with a four-membered central endo-cyclic Sn2O₂ unit in which the bridging oxygen atoms were tri-coordinated. Each bridging oxygen atom also connects with an exo-cyclic tin atom. The endo-cyclic and exo-cyclic tin atoms all were five-coordinated with distorted trigonal bipyramid geometry. The compounds 1 and 2 have strong anti-tumor activity in vitro.
- organotin compound,
- microwave solvothermal synthesis,
- in vitro antitumor activity
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