Citation: WANG Zhao-Lu, FENG Hui-Yun, LI Yan, XU Tao, XUE Ze-Chun, LI Lian-Zhi. A High Selective Fluorescent Ratio Sensor for Cd²⁺ Based on the Interaction of Peptide with Metal Ion[J]. Chinese Journal of Inorganic Chemistry, ;2015, 31(10): 1946-1952. doi: 10.11862/CJIC.2015.261 shu

A High Selective Fluorescent Ratio Sensor for Cd²⁺ Based on the Interaction of Peptide with Metal Ion

1.
School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China

Corresponding author: LI Lian-Zhi,
Received Date: 11 January 2015
Available Online: 23 July 2015
Fund Project: 山东省自然科学基金(No.ZR2011BL002)资助项目。 (No.ZR2011BL002)

A new fluorescent ratio chemosensor (Dansyl-Cys-Pro-Pro-Cys-Trp-NH₂) for metal ions has been synthesized via Fmoc solid-phase peptide synthesis. The interactions of the peptide with metal ions were investigated by fluorescence spectroscopy. Results showed that it showed high selectivity toward Cd²⁺ over other commonly coexistent metal ions. The peptide has the advantages of specific recognition to Cd²⁺, a good water-soluble and a fast response. The peptide tightly binds to Cd²⁺ with the binding constant of 3.0×10¹¹ L²·mol^-2 and the detection limit of 11.5 nmol·L^-1.
- peptide;Cd²⁺;fluorescent chemosensor;fluorescent ratio;fluorescence resonance energy transfer
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沈阳化工大学材料科学与工程学院沈阳 110142

A High Selective Fluorescent Ratio Sensor for Cd2+ Based on the Interaction of Peptide with Metal Ion

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通讯作者: 陈斌, bchen63@163.com

A High Selective Fluorescent Ratio Sensor for Cd²⁺ Based on the Interaction of Peptide with Metal Ion