Citation: Shen-wei Shi, Ting Li, Yang Wang, Wei-fu Dong. Preparation of Antibacterial Hybrid Silica Nanoparticle and Its Application in Polyurethane[J]. Acta Polymerica Sinica, ;2019, 50(7): 721-729. doi: 10.11777/j.issn1000-3304.2019.19009 shu

Preparation of Antibacterial Hybrid Silica Nanoparticle and Its Application in Polyurethane

School of Chemical Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University, Wuxi 214122

Corresponding author: Wei-fu Dong, wfdong@jiangnan.edu.cn
Received Date: 11 January 2019
Revised Date: 30 January 2019
Available Online: 19 March 2019

A series of reactive QACs with different chain lengths were prepared by inexpensive tertiary amine silane coupling agent, which were covalently grafted onto the surface of SiO₂ nanoparticles in one step via a modified Stöber method. This method can increase the graft ratio of QAC relative to the use of dry silica powder. The structure and appearance of hybrid SiO₂ nanoparticles were studied by Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), zeta potential and thermogravimetric analysis (TGA). The antibacterial activity of hybrid SiO₂ nanoparticles was evaluated by shake flask method. The composite films with excellent antimicrobial properties were obtained from a mixture of a polyurethane acrylate prepolymer and hybrid SiO₂ nanoparticles via UV curing. The standard antibacterial test method ISO 22196 was used to evaluate the antibacterial properties of the film. The results showed that the hybrid SiO₂ nanoparticles have a uniform particle size (~ 40 nm), a smooth spherical shape and a high positive charge on the surface. Antibacterial test results indicated that the hybrid SiO₂ nanoparticles have excellent antibacterial activity compared with pure SiO₂ nanoparticles, and can completely killed Escherichia coli and Staphylococcus epidermidis in 50 min. As the QAC alkyl chain grows, the antibacterial properties of the nanoparticles are further improved and SiO₂-Q-12 can killed two bacteria completely within 20 min. This is mainly due to the hybrid SiO₂ nanoparticles are light and have a high positive charge on the surface, so they can be quickly adsorbed on the surface of bacteria to achieve rapid sterilization. The hybrid SiO₂ nanoparticles were enriched on the surface of the film. Adding a small amount (5 wt%) of hybrid SiO₂ nanoparticles could endow the film with good antibacterial properties and high tensile strength. After the accelerated aging treatment of the composite film according to the national standard GB 15979-2002, it still possessed good antibacterial properties, indicating that the composite film has excellent antibacterial durability and stability. The test of the inhibition zone showed that the composite film was a contact antibacterial material, no antibacterial substance leaching, which was safer and more efficient.
- Covalent grafting,
- Hybrid SiO₂,
- Surface enrichment,
- Contact antibacterial
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