Citation: Xin Zhang, Zhihao Lu, Tianci Ren, Junxiang Tang, Shuo Li, Chenghao Zhu, Lijun Mao, Da Ma. Fluorescent "Texas-sized" macrocyclic receptors for the recognition and detection of nucleotides in water[J]. Chinese Chemical Letters, ;2025, 36(11): 110946. doi: 10.1016/j.cclet.2025.110946 shu

Fluorescent "Texas-sized" macrocyclic receptors for the recognition and detection of nucleotides in water

School of Pharmaceutical and Chemical Engineering & Institute for Advanced Studies, Taizhou University, Taizhou 318000, China

zx91318@163.com

dama@tzc.edu.cn

Received Date: 21 November 2024
Revised Date: 22 January 2025
Accepted Date: 11 February 2025
Available Online: 13 February 2025

Figures(4)

New water-soluble fluorescent tetracationic imidazolium-based macrocycles are synthesized via a modular S_N2 nucleophilic substitution reaction. The positive charge and acidic C–H sites of these macrocycles enable them to bind with nucleotides in water, driven by hydrogen bonds and electrostatic interactions. The binding is high affinity for suitable nucleotides. These properties position them as promising candidates for the selective sensing of nucleotides.
- Macrocycle,
- Water-soluble,
- Tetra-imidazolium salt,
- Nucleotide,
- Host-guest interaction
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