Citation: Weiqian Jin, Lin Liao, Tao Qin, Xiaoxuan Guan, Huyang Gao, Peng Liang, Ming Gao, Junyu Lu. Recent advances in nanomedicine therapy for bacterial pneumonia[J]. Chinese Chemical Letters, ;2025, 36(6): 110920. doi: 10.1016/j.cclet.2025.110920 shu

Recent advances in nanomedicine therapy for bacterial pneumonia

Weiqian Jin ^{a, 1} ,
Lin Liao ^{b, 1} ,
Tao Qin ^a ,
Xiaoxuan Guan ^c ,
Huyang Gao ^c ,
Peng Liang ^a ,
Ming Gao ^{c, *,} ,
Junyu Lu ^{a, *,}

a.
Intensive Care Unit, The Second Affiliated Hospital of Guangxi Medical University, Nanning 530007, China
b.
Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China
c.
Life Sciences Institute, Guangxi Medical University, Nanning 530021, China

Received Date: 3 December 2024
Revised Date: 31 January 2025
Accepted Date: 4 February 2025
Available Online: 4 February 2025

Figures(5)

Bacterial pneumonia is one of the most common infectious diseases, a great threat to the health of children and the elderly. In the clinic, due to the extensive use of antibiotics, multi-drug-resistant bacteria have increased in large numbers, seriously affects the treatment of patients with bacterial pneumonia. With the development of nanomedicine, it shows great potential in the treatment of bacterial pneumonia. In this review, it initially comprehensively describes the pathological process of bacterial pneumonia and the current status of its clinical treatment. Then it summarizes the strategies of nanomedicine for the treatment of bacterial pneumonia, including inorganic nanomaterials, polymer nanoparticles, natural source nanomaterials and artificial antimicrobial peptides, with a focus on novel nanomaterials for the treatment of bacterial pneumonia (biomimetic nanomaterials, nanovaccines and genetically engineered nanomaterials). Finally, the prospect of nanomedicine for bacterial pneumonia therapy is discussed in the hope of providing new ideas for the clinical treatment of bacterial pneumonia.
- Bacterial pneumonia,
- Antibiotic therapy,
- Nanomedicine,
- Immunotherapy,
- Antioxidant and anti-inflammation
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沈阳化工大学材料科学与工程学院沈阳 110142