Citation: Huan Ye, Ying Yang, Lirong Jiang, Taotao Zhe, Junchao Xu, Lintao Zeng. An intelligent sensing platform for discrimination of formaldehyde and nitrite in food[J]. Chinese Chemical Letters, ;2025, 36(11): 110840. doi: 10.1016/j.cclet.2025.110840 shu

An intelligent sensing platform for discrimination of formaldehyde and nitrite in food

Huan Ye ^{a, 1} ,
Ying Yang ^{a, 1} ,
Lirong Jiang ^b ,
Taotao Zhe ^a ,
Junchao Xu ^{c, *,} ,
Lintao Zeng ^{a, *,}

a.
Guangxi Key Laboratory of Clean Pulp & Papermaking and Pollution Control, School of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China
b.
Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University, Nanning 530006, China
c.
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

JunchaoXu@hun.edu.cn

zlt1981@126.com

Received Date: 30 October 2024
Revised Date: 4 January 2025
Accepted Date: 9 January 2025
Available Online: 10 January 2025

Figures(6)

Formaldehyde (FA) and excessive nitrite (NO₂⁻) are highly carcinogenic compounds that pose serious risks to human health. In this study, we designed a sensing platform 8-hydrazine-boron dipyrromethene (OPTY) for the detection of FA and nitrite in food. Upon aldimine condensation with FA, OPTY produced strong blue fluorescence. By contrast, NO₂⁻ underwent an intramolecular cyclization cascade reaction with OPTY to boast bright green fluorescence. OPTY has the advantages of high signal-to-noise ratio, good selectivity, and a low limit of detection (LOD = 26.5 nmol/L for FA, LOD = 20.8 nmol/L for NO₂⁻). Furthermore, OPTY was fabricated into a portable sensing chip, which was combined with smartphone to form a portable sensing platform. This platform has been successfully applied for the determination of FA/NO₂⁻ in meat and seafood with high accuracy (93.49%–102.35%). Therefore, the intelligent sensing platform can realize on-site visual detection of FA/NO₂⁻ content in food, demonstrating great potential for ensuring food safety.
- Fluorescent probe,
- Formaldehyde,
- Nitrite,
- Discrimination detection,
- Intelligent sensing platform
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沈阳化工大学材料科学与工程学院沈阳 110142