Citation: Xinhui Fang, Xinrui Wang, Bin Ding. Applications of luminescent metal-organic frameworks as pioneering biosensors for biological and chemical detection[J]. Chinese Chemical Letters, ;2025, 36(8): 110453. doi: 10.1016/j.cclet.2024.110453 shu

Applications of luminescent metal-organic frameworks as pioneering biosensors for biological and chemical detection

Tianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, Tianjin 300387, China

wangxinrui-tjnu@outlook.com

hxxydb@tjnu.edu.cn

Received Date: 7 July 2024
Revised Date: 9 August 2024
Accepted Date: 12 September 2024
Available Online: 12 September 2024

Figures(10)

Biological sensing technology plays a crucial role in various key areas such as disease diagnosis, environmental monitoring, and biotechnology. Luminescent metal-organic frameworks (LMOFs), with their remarkable advantages including large surface area, customizable pore structures, and highly active functional sites, have emerged as a frontier in biosensor research. This review clarifies the potential of LMOFs in biological sensing applications, with particular emphasis on their efficient performance in detecting amino acids, biomarkers, and drugs, explore the possibility of integrating LMOFs with portable analytical techniques, providing an innovative perspective for advancing luminescence detection technology. Some effective characterization methods to encode these sensing mechanisms including Förster resonance energy transfer (FRET), photoinduced electron transfer (PET) and thermally activated energy back transfer (BENT) highlighted their connection and difference. Finally, the article summarizes the achievements of LMOFs in biological sensing and provides a perspective on future research directions and potential applications, aiming to propel the continuous development of this field.
- LMOFs,
- Luminescence,
- Amino acids,
- Biomarkers,
- Pharmaceuticals
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沈阳化工大学材料科学与工程学院沈阳 110142