Citation: Tianyu Sun, Zhoujun Dong, Paul Michael Malugulu, Tengfei Zhen, Lei Wang, Yao Chen, Haopeng Sun. Advances in design strategies and imaging applications of specific butyrylcholinesterase probes[J]. Chinese Chemical Letters, ;2025, 36(7): 110451. doi: 10.1016/j.cclet.2024.110451 shu

Advances in design strategies and imaging applications of specific butyrylcholinesterase probes

Tianyu Sun ^a ,
Zhoujun Dong ^c ,
Paul Michael Malugulu ^a ,
Tengfei Zhen ^a ,
Lei Wang ^a ,
Yao Chen ^{b, *,} ,
Haopeng Sun ^{a, *,}

a.
School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
b.
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
c.
School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China

Received Date: 4 July 2024
Revised Date: 8 September 2024
Accepted Date: 11 September 2024
Available Online: 12 September 2024

Figures(22)

Butyrylcholinesterase (BChE) is a pivotal enzyme that degrades the neurotransmitter acetylcholine, which is related to learning and memory, into choline and acetic acid. BChE activity is strongly associated with various diseases, including Alzheimer's disease, multiple sclerosis, diabetes, and lipid metabolism disorders. It also possesses pharmacological properties for combating cocaine addiction and detoxifying organophosphate poisoning. Given the significant importance of BChE in the biological and medical fields, detecting its activity and understanding its expression in the body are crucial for advancing related research. Herein, a brief review of recently reported specific fluorescence or chemiluminescence probes for quantifying and real-time monitoring BChE is provided. By utilizing unique recognition groups, these probes achieve highly selective identification of BChE and effectively resist interference from other biological factors. Probes demonstrate excellent performance in measuring BChE activity, screening BChE inhibitors, and locating BChE in cells and mice. These also offer strong technical support for early diagnosis, precise intervention, and effective treatment of diseases with pathological changes in BChE.
- Butyrylcholinesterase,
- Fluorescent probes,
- Chemiluminescence,
- "AND" logic probes,
- Quantitative detection,
- Real-time monitoring
1. [1]
  S. Darvesh, D.A. Hopkins, C. Geula, Nat. Rev. Neurosci. 4 (2003) 131–138. doi: 10.1038/nrn1035
2. [2]
  M.E. Hasselmo, B.P. Anderson, J.M. Bower, J. Neurophysiol. 67 (1992) 1230–1246. doi: 10.1152/jn.1992.67.5.1230
3. [3]
  M. Sarter, J.P. Bruno, Brain Res. Rev. 23 (1997) 28–46.
4. [4]
  J. Haam, J.L. Yakel, J. Neurochem. 142 (2017) 111–121. doi: 10.1111/jnc.14052
5. [5]
  R.A. Bekdash, Int. J. Mol. Sci. 22 (2021) 1273. doi: 10.3390/ijms22031273
6. [6]
  Z. Chen, J. Huang, S. Yang, F. Hong, Molecules 27 (2022) 1816. doi: 10.3390/molecules27061816
7. [7]
  N.H. Greig, T. Utsuki, Q. Yu, et al., Curr. Med. Res. Opin. 17 (2001) 159–165. doi: 10.1185/0300799039117057
8. [8]
  J.L. Sussman, M. Harel, F. Frolow, et al., Science 253 (1991) 872–879. doi: 10.1126/science.1678899
9. [9]
  D. Kaplan, A. Ordentlich, D. Barak, et al., Biochemistry 40 (2001) 7433–7445. doi: 10.1021/bi010181x
10. [10]
  A. Saxena, A.M. Redman, X. Jiang, et al., Biochemistry 36 (1997) 14642–14651. doi: 10.1021/bi971425+
11. [11]
  D.F. Garcia, T.G. Oliveira, G.A. Molfetta, et al., Genet. Mol. Biol. 34 (2011) 40–44. doi: 10.1590/S1415-47572011000100008
12. [12]
  D.A. Gorelick, Drug Alcohol Depend. 48 (1997) 159–165.
13. [13]
  O. Lockridge, R.B. Jr. Norgren, R.C. Johnson, T.A. Blake, Chem. Res. Toxicol. 29 (2016) 1381–1392. doi: 10.1021/acs.chemrestox.6b00228
14. [14]
  A.J. Franjesevic, S.B. Sillart, J.M. Beck, et al., Chemistry (Easton) 25 (2019) 5337–5371. doi: 10.1002/chem.201805075
15. [15]
  M. Scheiner, M. Hoffmann, F. He, et al., J. Med. Chem. 64 (2021) 9302–9320. doi: 10.1021/acs.jmedchem.1c00534
16. [16]
  E.K. Perry, R.H. Perry, G. Blessed, B.E. Tomlinson, Neuropathol. Appl. Neurobiol. 4 (1978) 273–277. doi: 10.1111/j.1365-2990.1978.tb00545.x
17. [17]
  Q. Li, Y. Chen, S. Xing, et al., J. Med. Chem. 64 (2021) 6856–6876. doi: 10.1021/acs.jmedchem.1c00167
18. [18]
  R. Ghobadian, R. Esfandyari, H. Nadri, et al., Mol. Divers. 24 (2020) 211–223. doi: 10.1007/s11030-019-09943-6
19. [19]
  X. Lu, N. Qin, Y. Liu, et al., Eur. J. Med. Chem. 243 (2022) 114729.
20. [20]
  C. Du, L. Wang, Q. Guan, et al., J. Med. Chem. 65 (2022) 11365–11387. doi: 10.1021/acs.jmedchem.2c00944
21. [21]
  R. Ullah, G. Ali, F. Subhan, et al., Int. Immunopharmacol. 100 (2021) 108083.
22. [22]
  K. OzadaliSari, T. Tüylü Küçükkılınç, B. Ayazgok, et al., Bioorganic Chem. 72 (2017) 208–214. doi: 10.1016/j.bioorg.2017.04.018
23. [23]
  A.L. Guillozet, M.M. Mesulam, J.F. Smiley, D.C. Mash, Ann. Neurol. 42 (1997) 909–918. doi: 10.1002/ana.410420613
24. [24]
  D.R. DeBay, G.A. Reid, I.R. Macdonald, et al., Brain Res. 1671 (2017) 102–110. doi: 10.1016/j.brainres.2017.07.009
25. [25]
  I. Mateo, J. Llorca, J. Infante, et al., Eur. J. Neurol. 15 (2008) 219–222. doi: 10.1111/j.1468-1331.2008.02059.x
26. [26]
  M.W.D. Thorne, M.K. Cash, G.A. Reid, et al., Mol. Imaging Biol. 23 (2021) 127–138. doi: 10.1007/s11307-020-01540-6
27. [27]
  S. Darvesh, A.M. LeBlanc, I.R. Macdonald, et al., Chem. Biol. Interact. 187 (2010) 425–431. doi: 10.1016/j.cbi.2010.01.037
28. [28]
  M. Reale, F. De Angelis, M. Di Nicola, et al., Int. J. Mol. Sci. 13 (2012) 12656–12664. doi: 10.3390/ijms131012656
29. [29]
  M. Di Bari, M. Reale, M. Di Nicola, et al., Int. J. Mol. Sci. 17 (2016) 2009. doi: 10.3390/ijms17122009
30. [30]
  I.R. Pottie, E.A. Higgins, R.A. Blackman, et al., ACS Chem. Neurosci. 2 (2011) 151–159. doi: 10.1021/cn100090g
31. [31]
  M. Gok, C. Cicek, E. Bodur, J. Neurochem. 168 (2024) 381–385. doi: 10.1111/jnc.15833
32. [32]
  L. FurtadoAlle, L.V. Tureck, C.S. de Oliveira, et al., Chem. Biol. Interact. 383 (2023) 110680.
33. [33]
  B. Li, E.G. Duysen, O. Lockridge, Chem. Biol. Interact. 175 (2008) 88–91. doi: 10.1016/j.cbi.2008.03.009
34. [34]
  V.P. Chen, Y. Gao, L. Geng, et al., Endocrinology 157 (2016) 3086–3095. doi: 10.1210/en.2016-1166
35. [35]
  V.P. Chen, Y. Gao, L. Geng, et al., Proc. Natl. Acad. Sci. 112 (2015) 2251–2256. doi: 10.1073/pnas.1421536112
36. [36]
  L.M. Schopfer, O. Lockridge, S. Brimijoin, Gen. Comp. Endocrinol. 224 (2015) 61–68.
37. [37]
  M.G. Akimov, D.S. Kudryavtsev, E.V. Kryukova, et al., Biomolecules 10 (2020) 283. doi: 10.3390/biom10020283
38. [38]
  M. Gok, C. Cicek, S. Sari, E. Bodur, Biochimie 204 (2023) 127–135. doi: 10.1016/j.biochi.2022.09.008
39. [39]
  D. Wang, K.S. Tan, W. Zeng, et al., Life Sci. 293 (2022) 120336.
40. [40]
  K. Dave, S. Katyare, J. Endocrinol. 175 (2002) 241–250. doi: 10.1677/joe.0.1750241
41. [41]
  A. Tvarijonaviciute, J.J. Ceron, M. Caldin, Vet. J. 192 (2012) 494–497.
42. [42]
  V.P. Chen, Y. Gao, L. Geng, S. Brimijoin, Int. J. Obes. 41 (2017) 1413–1419. doi: 10.1038/ijo.2017.123
43. [43]
  S. ShenharTsarfaty, T. Bruck, E.R. Bennett, et al., J. Cell. Mol. Med. 15 (2011) 1747–1756. doi: 10.1111/j.1582-4934.2010.01165.x
44. [44]
  L. Turecky, V. Kupcova, M. Durfinova, E. Uhlikova, Bratisl. Med. J. 122 (2021) 689–694. doi: 10.4149/bll_2021_110
45. [45]
  O.O. Ogunkeye, A.I. Roluga, Pathophysiology 13 (2006) 91–93.
46. [46]
  R. Yu, Y. Guo, Y. Dan, et al., BMC Med. Genet. 19 (2018) 58. doi: 10.1186/s12881-018-0561-5
47. [47]
  J. Liu, T. Tian, X. Liu, Z. Cui, J. Immunol. Res. 2022 (2022) 6051092. doi: 10.1155/2022/6051092
48. [48]
  M. Pohanka, Bratisl. Med. J. 114 (2013) 726–734. doi: 10.4149/bll_2013_153
49. [49]
  J. BaranowskaKortylewicz, Z.P. Kortylewicz, E.M. McIntyre, et al., J. Pediatr. Hematol. Oncol. 44 (2022) 293–304. doi: 10.1097/mph.0000000000002285
50. [50]
  K. Prabhu, Australas. Med. J. 4 (2011) 374–378. doi: 10.4066/AMJ.2011.569
51. [51]
  R. Kumar, S. Razab, K. Prabhu, et al., J. Cancer Res. Ther. 13 (2017) 367.
52. [52]
  N. Poetsch, A. Sturdza, S. Aust, et al., Strahlenther. Onkol. 195 (2019) 430–440. doi: 10.1007/s00066-019-01430-z
53. [53]
  E.V. Klocker, D.A. Barth, J.M. Riedl, et al., Cancers (Basel) 12 (2020) 1154. doi: 10.3390/cancers12051154
54. [54]
  Y. Miao, N. He, J. Zhu, Chem. Rev. 110 (2010) 5216–5234. doi: 10.1021/cr900214c
55. [55]
  O. Holas, K. Musilek, M. Pohanka, K. Kuca, Expert Opin. Drug Discov. 7 (2012) 1207–1223. doi: 10.1517/17460441.2012.729037
56. [56]
  M. Pohanka, Int. J. Electrochem. Sci. 11 (2016) 7440–7452. doi: 10.20964/2016.09.16
57. [57]
  X. Zhang, C. Zhao, Y. Shu, J. -H. Wang, Anal. Chem. 91 (2019) 15866–15872. doi: 10.1021/acs.analchem.9b04304
58. [58]
  G.L. Ellman, K.D. Courtney, V. Andres, R.M. Featherstone, Biochem. Pharmacol. 7 (1961) 88–95. doi: 10.1016/0006-2952(61)90145-9
59. [59]
  M. Pohanka, Talanta 119 (2014) 412–416.
60. [60]
  S. Yang, Q. Sun, H. Xiong, et al., Chem. Commun. 53 (2017) 3952–3955. doi: 10.1039/c7cc00577f
61. [61]
  Z. Chen, X. Ren, X. Meng, et al., Biosens. Bioelectron. 44 (2013) 204–209.
62. [62]
  X. Xu, Y. Cen, G. Xu, et al., Biosens. Bioelectron. 131 (2019) 232–236. doi: 10.3390/pr7040232
63. [63]
  J. Zhang, M. Wang, J. Liu, et al., J. Agric. Food Chem. 71 (2023) 11884–11891. doi: 10.1021/acs.jafc.3c02902
64. [64]
  M. Yang, J. Huang, J. Fan, et al., Chem. Soc. Rev. 49 (2020) 6800–6815. doi: 10.1039/d0cs00348d
65. [65]
  H. Feng, Q. Meng, H.T. Ta, R. Zhang, New J. Chem. 44 (2020) 12890–12896. doi: 10.1039/d0nj02762f
66. [66]
  J.L. Kolanowski, F. Liu, E.J. New, Chem. Soc. Rev. 47 (2018) 195–208. doi: 10.1039/c7cs00528h
67. [67]
  J.M. An, K.O. Jung, M.S. Oh, D. Kim, Dyes Pigments 215 (2023) 111267.
68. [68]
  J. Zhou, H. Ma, Chem. Sci. 7 (2016) 6309–6315. doi: 10.1039/c6sc02500e
69. [69]
  S. Kang, S. Lee, W. Yang, et al., Org. Biomol. Chem. 14 (2016) 8815–8820.
70. [70]
  H. -W. Liu, L. Chen, C. Xu, et al., Chem. Soc. Rev. 47 (2018) 7140–7180. doi: 10.1039/c7cs00862g
71. [71]
  S. Lushchekina, P. Masson, Toxicology 409 (2018) 91–102. doi: 10.1016/j.tox.2018.07.020
72. [72]
  X. Chen, L. Fang, J. Liu, C. Zhan, J. Phys. Chem. B 115 (2011) 1315–1322. doi: 10.1021/jp110709a
73. [73]
  S. Liu, H. Xiong, J. Yang, et al., ACS Sens. 3 (2018) 2118–2128. doi: 10.1021/acssensors.8b00697
74. [74]
  J. Ma, X. Lu, H. Zhai, et al., Talanta 219 (2020) 121278.
75. [75]
  Y. Yang, L. Zhang, J. Wang, et al., Anal. Chem. 94 (2022) 13498–13506. doi: 10.1021/acs.analchem.2c02627
76. [76]
  L. Wang, T. Sun, T. Zhen, et al., J. Med. Chem. 67 (2024) 6793–6809. doi: 10.1021/acs.jmedchem.4c00355
77. [77]
  T. Cao, L. Zheng, L. Zhang, et al., Sens. Actuators B: Chem. 330 (2021) 129348.
78. [78]
  Z. Yu, X. Li, X. Lu, Y. Guo, New J. Chem. 46 (2022) 12034–12040. doi: 10.1039/d2nj01678h
79. [79]
  Y. Yang, L. Zhang, J. Wang, et al., Dyes Pigments 206 (2022) 110596.
80. [80]
  Q. Zhang, C. Fu, X. Guo, et al., ACS Sens. 6 (2021) 1138–1146. doi: 10.1021/acssensors.0c02398
81. [81]
  X. Liang, L. Zhang, B. Shi, et al., Talanta 220 (2020) 121433. doi: 10.1016/j.talanta.2020.121433
82. [82]
  W. Zhang, J. Zhang, C. Qin, et al., Anal. Chim. Acta 1235 (2022) 340540. doi: 10.1016/j.aca.2022.340540
83. [83]
  S. Zhang, D. Chen, L. Yan, et al., Microchem. J. 157 (2020) 105066.
84. [84]
  L. Dai, Q. Zhang, Q. Ma, W. Lin, Coord. Chem. Rev. 489 (2023) 215193.
85. [85]
  M. Zhu, F. Fan, Z. Zhao, et al., J. Mol. Liq. 296 (2019) 111832.
86. [86]
  L. Yan, L. Tang, X. Wu, L. Li, Crit. Rev. Anal. Chem. (2024), doi.org/10.1080/10408347.2024.2354328. doi: 10.1080/10408347.2024.2354328
87. [87]
  W. Kang, M. Ma, L. Xu, et al., Anal. Chim. Acta 1282 (2023) 341932. doi: 10.1016/j.aca.2023.341932
88. [88]
  Y. Jiang, H. Cui, Q. Yu, Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 308 (2024) 123801. doi: 10.1016/j.saa.2023.123801
89. [89]
  B. Yang, Y. He, X. Ding, et al., Dyes Pigments 229 (2024) 112295.
90. [90]
  W. Wang, X. Chen, Y. Zhang, et al., Chemosensors 12 (2024) 100. doi: 10.3390/chemosensors12060100
91. [91]
  Z. Zhang, J. Li, B. Yang, et al., Talanta 279 (2024) 126587. doi: 10.1016/j.talanta.2024.126587
92. [92]
  H. Li, X. Li, C. Yan, et al., Front. Bioeng. Biotechnol. 12 (2024) 1387146. doi: 10.3389/fbioe.2024.1387146
93. [93]
  Z. Guo, J. Peng, Z. Zhou, et al., Anal. Methods. 16 (2024) 4054–4059. doi: 10.1039/d4ay00662c
94. [94]
  J. Xu, B. Zhang, Y. Zhang, et al., Talanta 253 (2023) 124037.
95. [95]
  H. Dong, Y. Zhou, Y. Hao, et al., Biosens. Bioelectron. 165 (2020) 112402. doi: 10.1016/j.bios.2020.112402
96. [96]
  E. Lim, J. Ricci, M. Jung, Molecules 16 (2011) 9886–9899. doi: 10.3390/molecules16129886
97. [97]
  W. Li, R. Li, R. Chen, et al., Anal. Chem. 94 (2022) 7996–8004. doi: 10.1021/acs.analchem.2c01048
98. [98]
  H. Dong, L. Zhao, T. Wang, et al., Anal. Chem. 95 (2023) 8340–8347. doi: 10.1021/acs.analchem.3c00974
99. [99]
  L. Xu, M. Ma, J. Li, et al., Sens. Actuators B Chem. 394 (2023) 134432.
100. [100]
  A. Acari, T. Almammadov, M. Dirak, et al., J. Mater. Chem. B 11 (2023) 68881–6888.
101. [101]
  A.R. Lippert, ACS Cent. Sci. 3 (2017) 269–271. doi: 10.1021/acscentsci.7b00107
102. [102]
  Y. Gao, Y. Lin, T. Liu, et al., Chin. Chem. Lett. 30 (2019) 63–66.
103. [103]
  S. Bai, S. Huang, T. Luo, et al., Chin. Chem. Lett. (2024), https://doi.org/10.1016/j.cclet.2024.110054. doi: 10.1016/j.cclet.2024.110054
104. [104]
  M.H. Lee, J.S. Kim, J.L. Sessler, Chem. Soc. Rev. 44 (2015) 4185–4191. doi: 10.1039/c4cs00280f
105. [105]
  Y. Qi, Y. Li, M. Tan, et al., Coord. Chem. Rev. 486 (2023) 215130.
106. [106]
  X. Yang, C. Li, P. Li, Q. Fu, Theranostics 13 (2023) 2632–2656. doi: 10.7150/thno.82323
107. [107]
  R. Gui, H. Jin, X. Bu, et al., Coord. Chem. Rev. 383 (2019) 82–103.
108. [108]
  B. Zhang, S. Qin, N. Wang, et al., Talanta 266 (2024) 124971. doi: 10.1016/j.talanta.2023.124971
109. [109]
  J. Xu, J. Pan, X. Jiang, et al., Biosens. Bioelectron. 77 (2016) 725–732.
110. [110]
  Y. Cui, F. Chen, X. Yin, Biosens. Bioelectron. 135 (2019) 208–215. doi: 10.1016/j.bios.2019.04.008
111. [111]
  C. Wan, J. Li, J. Gao, et al., Dyes Pigments 197 (2022) 109874.
112. [112]
  J. Luo, Z. Xie, J.W.Y. Lam, et al., Chem. Commun. (2001) 1740–1741.
113. [113]
  D. Wang, H. Su, R.T.K. Kwok, et al., Chem. Sci. 9 (2018) 3685–3693. doi: 10.1039/c7sc04963c
114. [114]
  Y. Huang, J. Xing, Q. Gong, et al., Nat. Commun. 10 (2019) 169.
115. [115]
  R. Hu, A. Qin, B.Z. Tang, Prog. Polym. Sci. 100 (2020) 101176.
116. [116]
  Y. Hong, J.W.Y. Lam, B.Z. Tang, Chem. Commun. (2009) 4332–4353. doi: 10.1039/b904665h
117. [117]
  C. Xiang, J. Xiang, X. Yang, et al., J. Mater. Chem. B 10 (2022) 4254–4260. doi: 10.1039/d2tb00422d
118. [118]
  J.F. Lamère, N. Saffon, I. Dos Santos, S. Fery-Forgues, Langmuir 26 (2010) 10210–10217. doi: 10.1021/la100349d
119. [119]
  R. Hu, S. Li, Y. Zeng, et al., Phys. Chem. Chem. Phys. 13 (2011) 2044–2051.
120. [120]
  Y. Qian, S. Li, G. Zhang, et al., J. Phys. Chem. B 111 (2007) 5861–5868. doi: 10.1021/jp070076i
121. [121]
  M. Ikegami, T. Arai, J. Chem. Soc. Perkin Trans. 2 (2002) 1296–1301.
122. [122]
  J. Ding, R. Xiao, A. Bi, et al., Chin. Chem. Lett. 34 (2023) 108273.
123. [123]
  M. Liu, S. Zhong, B. Feng, et al., Chin. Chem. Lett. 34 (2023) 107940.
124. [124]
  A.C. Sedgwick, L. Wu, H. Han, et al., Chem. Soc. Rev. 47 (2018) 8842–8880. doi: 10.1039/c8cs00185e
125. [125]
  Y. Li, D. Dahal, C.S. Abeywickrama, Y. Pang, ACS Omega 6 (2021) 6547–6553. doi: 10.1021/acsomega.0c06252
126. [126]
  B. Feng, Y. Zhu, J. Wu, et al., Chin. Chem. Lett. 32 (2021) 3057–3060.
127. [127]
  X. Pei, Y. Fang, H. Gu, et al., Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 287 (2023) 122044. doi: 10.1016/j.saa.2022.122044
128. [128]
  W. Yuan, C. Wan, J. Zhang, et al., Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 297 (2023) 122719. doi: 10.1016/j.saa.2023.122719
129. [129]
  Z. Yu, Y. Ma, S. Xu, et al., Sens. Actuators B Chem. 410 (2024) 135662.
130. [130]
  G. Chen, H. Feng, X. Jiang, et al., Anal. Chem. 90 (2018) 1643–1651. doi: 10.1021/acs.analchem.7b02976
131. [131]
  G. Chen, H. Feng, W. Xi, et al., Analyst 144 (2019) 559–566. doi: 10.1039/c8an01808a
132. [132]
  Th. Forster, Naturwissenschaften 33 (1946) 166–175.
133. [133]
  W.R. Algar, N. Hildebrandt, S.S. Vogel, I.L. Medintz, Nat. Methods 16 (2019) 815–829. doi: 10.1038/s41592-019-0530-8
134. [134]
  C.D.F. Martins, M.M.M. Raposo, S.P.G. Costa, Proceedings 41 (2019) 34. doi: 10.3390/ecsoc-23-06613
135. [135]
  E.D. Matayoshi, G.T. Wang, G.A. Krafft, J. Erickson, Science 247 (1990) 954–958. doi: 10.1126/science.2106161
136. [136]
  A.A. Gershkovich, V.V. Kholodovych, J. Biochem. Biophys. Methods 33 (1996) 135–162. doi: 10.1016/s0165-022x(96)00023-1
137. [137]
  S. Grahn, D. Ullmann, H. -D. Jakubke, Anal. Biochem. 265 (1998) 225–231. doi: 10.1006/abio.1998.2902
138. [138]
  J. Guo, C. Xu, X. Li, S. Chen, PLoS ONE 9 (2014) e114124. doi: 10.1371/journal.pone.0114124
139. [139]
  D.L. Goulet, U. Fraaz, C.J. Zulich, et al., Anal. Biochem. 604 (2020) 113826.
140. [140]
  Z. Bánóczi, A. Alexa, A. Farkas, et al., Bioconjug. Chem. 19 (2008) 1375–1381. doi: 10.1021/bc800021y
141. [141]
  M. Gong, C. Dai, S. Severance, et al., Catalysts 10 (2020) 1169. doi: 10.3390/catal10101169
142. [142]
  K. Blennow, H. Zetterberg, J. Intern. Med. 284 (2018) 643–663. doi: 10.1111/joim.12816
143. [143]
  Y.Y. Broza, X. Zhou, M. Yuan, et al., Chem. Rev. 119 (2019) 11761–11817. doi: 10.1021/acs.chemrev.9b00437
144. [144]
  J.D. Schiffman, P.G. Fisher, P. Gibbs, Am. Soc. Clin. Oncol. Educ. Book (2015) 57–65.
145. [145]
  S. Wang, K. Zhang, S. Tan, et al., Mol. Cancer 20 (2021) 13.
146. [146]
  T. Rehman, M.A. Shabbir, M. Inam-Ur-Raheem, et al., Food Sci. Nutr. 8 (2020) 4696–4707. doi: 10.1002/fsn3.1818
147. [147]
  M. Chen, C. Wang, Z. Ding, et al., ACS Cent. Sci. 8 (2022) 837–844. doi: 10.1021/acscentsci.2c00387
148. [148]
  L. Wu, A.C. Sedgwick, X. Sun, et al., Acc. Chem. Res. 52 (2019) 2582–2597. doi: 10.1021/acs.accounts.9b00302
149. [149]
  H. Niu, X. Mi, X. Hua, et al., Anal. Chim. Acta 1192 (2022) 339341.
150. [150]
  A.C. Sedgwick, H.H. Han, J.E. Gardiner, et al., Chem. Sci. 9 (2018) 3672–3676. doi: 10.1039/c8sc00733k
151. [151]
  J.Z. Li, Y. Sun, C. Wang, et al., Anal. Chem. 91 (2019) 11946–11951. doi: 10.1021/acs.analchem.9b02749
152. [152]
  A. Romieu, Org. Biomol. Chem. 13 (2015) 1294–1306.
153. [153]
  X. Zhao, J. Kang, Y.P. Shi, Anal. Chem. 94 (2022) 6574–6581. doi: 10.1021/acs.analchem.2c00406
154. [154]
  C. Liu, R. Zhang, W. Zhang, et al., J. Am. Chem. Soc. 141 (2019) 8462–8472. doi: 10.1021/jacs.8b13898
155. [155]
  X. Yang, X. Han, Y. Zhang, et al., Anal. Chem. 92 (2020) 12002–12009. doi: 10.1021/acs.analchem.0c02509
156. [156]
  S. Yoo, M.S. Han, Chem. Commun. 55 (2019) 14574–14577. doi: 10.1039/c9cc07737e
157. [157]
  Z. Chen, C. Zhong, Neurosci. Bull. 30 (2014) 271–281. doi: 10.1007/s12264-013-1423-y
158. [158]
  D. Praticò, Trends Pharmacol. Sci. 29 (2008) 609–615.
159. [159]
  T.S. Leyane, S.W. Jere, N.N. Houreld, Int. J. Mol. Sci. 23 (2022) 7273. doi: 10.3390/ijms23137273
160. [160]
  P. Zhang, C. Fu, H. Liu, et al., Anal. Chem. 93 (2021) 11337–11345. doi: 10.1021/acs.analchem.1c02943
161. [161]
  K. Pravalika, D. Sarmah, H. Kaur, et al., ACS Chem. Neurosci. 9 (2018) 421–430. doi: 10.1021/acschemneuro.7b00462
162. [162]
  Y.W. Yap, M. Whiteman, N.S. Cheung, Cell. Signal. 19 (2007) 219–228.
163. [163]
  Y. Duan, S. Wang, F. Cao, et al., Ind. Eng. Chem. Res. 59 (2020) 992–999.
164. [164]
  C.M.C. Andrés, J.M. Pérez de la Lastra, C.A. Juan, et al., Int. J. Mol. Sci. 23 (2022) 10735. doi: 10.3390/ijms231810735
165. [165]
  J. Cao, D.M. Jiang, X. Ren, et al., Dyes Pigments 146 (2017) 279–286.
166. [166]
  F. Tian, Y. Jia, Y. Zhang, et al., Biosens. Bioelectron. 86 (2016) 68–74.
167. [167]
  R.A. Maki, V.A. Tyurin, R.C. Lyon, et al., J. Biol. Chem. 284 (2009) 3158–3169. doi: 10.1074/jbc.M807731200
168. [168]
  S. Samanta, T. Govindaraju, ACS Chem. Neurosci. 10 (2019) 4847–4853. doi: 10.1021/acschemneuro.9b00554
169. [169]
  J. Guo, J. Sun, D. Liu, et al., Anal. Chem. 95 (2023) 16868–16876. doi: 10.1021/acs.analchem.3c02634
170. [170]
  S. Xing, Q. Li, B. Xiong, et al., Med. Res. Rev. 41 (2021) 858–901. doi: 10.1002/med.21745
171. [171]
  P. GómezRamos, M.A. Morán, Mol. Chem. Neuropathol. 30 (1997) 161–173.
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沈阳化工大学材料科学与工程学院沈阳 110142