Citation: Qi Li, Zi-Lu Wang, Yun-He Xu. Copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters for synthesis of functionalized 2, 3-allenoates[J]. Chinese Chemical Letters, ;2023, 34(9): 108150. doi: 10.1016/j.cclet.2023.108150 shu

Copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters for synthesis of functionalized 2, 3-allenoates

Department of Chemistry, University of Science and Technology of China, Hefei 230026, China

xyh0709@ustc.edu.cn

Received Date: 17 September 2022
Revised Date: 7 January 2023
Accepted Date: 11 January 2023
Available Online: 13 January 2023

Figures(6)

Herein, copper-catalyzed 1,4-protosilylation and 1,4-protoborylation of enynic orthoesters have been developed. The enynic orthoesters as precursors of unstable enynic esters were applied to produce the functionalized 2, 3-allenoate products. Meanwhile, the asymmetric 1,4-protosilylation of enynic orthoesters with PhMe₂Si-Bpin was also studied. The chiral monopyridine imidazoline ligand was efficient to provide the asymmetric 1,4-protosilylation products with high enantioselectivity.
- Copper-catalyzed,
- 1,4-Protosilylation,
- 1,4-Protoborylation,
- 2, 3-Allenoate,
- Enynic orthoesters
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