Citation: Ziyao Wang, Ziyan Feng, Fangxue Du, Xi Xiang, Xinyi Tang, Li Qiu, Zhiyong Qian. Recent progress in theranostic microbubbles[J]. Chinese Chemical Letters, ;2023, 34(9): 108137. doi: 10.1016/j.cclet.2023.108137 shu

Recent progress in theranostic microbubbles

Ziyao Wang ^{a, 1} ,
Ziyan Feng ^{a, 1} ,
Fangxue Du ^a ,
Xi Xiang ^a ,
Xinyi Tang ^a ,
Li Qiu ^{a, *,} ,
Zhiyong Qian ^{b, *,}

a.
Department of Medical Ultrasound, West China Hospital of Sichuan University, Chengdu 610041, China
b.
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu 610041, China

wsqiuli@vip.126.com

anderson-qian@163.com

^†

Received Date: 19 September 2022
Revised Date: 5 January 2023
Accepted Date: 6 January 2023
Available Online: 7 January 2023

Figures(6)

Ultrasonography is an important complement to clinical diagnosis, and the application of microbubbles effectively improved diagnostic accuracy in echography. In scientific research, the sizes of microbubbles range from nanometers to microns. By optimizing the fabrication process, bubble sizes and ultrasound parameters, microbubbles can also be used for drug delivery and therapeutic monitoring. In this review, we summarize the recent advances in the diagnosis and treatment of microbubbles according to their different components. Modification of microbubble shells allows for more accurate imaging and detection and the combined utilization of US-targeted MB destruction (UTMD) allows for non-invasive, precise and targeted delivery of drug molecules to pathological tissues. These features pave the way for the emerge of theranostic microbubbles by combination of functional compositions and the application of multifunctional materials. Theranostic microbubbles allow for the simultaneous process of diagnosis, visualization of drug delivery and therapeutic monitoring. Ultimately, theranostic microbubbles are promising in clinical practice and would enhance contrast-enhanced US (CEUS) to a new qualitative level.
- Microbubbles,
- Nanobubbles,
- Ultrasound,
- Ceus,
- Cavitation,
- Theranostics
1. [1]
  V. Paefgen, D. Doleschel, F. Kiessling, Front. Pharmacol. 6(2015) 197.
2. [2]
  A.S. Hannah, G.P. Luke, S.Y. Emelianov, Theranostics 6(2016) 1866–1876. doi: 10.7150/thno.14961
3. [3]
  E.G. Schutt, D.H. Klein, R.M. Mattrey, J.G. Riess, Angew. Chem. Int. Ed. 42(2003) 3218–3235. doi: 10.1002/anie.200200550
4. [4]
  J.N. Meegoda, S. Aluthgun Hewage, J.H. Batagoda, Environ. Eng. Sci. 35(2018) 1216–1227. doi: 10.1089/ees.2018.0203
5. [5]
  J. Bzyl, W. Lederle, A. Rix, et al., Eur. Radiol. 21(2011) 1988–1995. doi: 10.1007/s00330-011-2138-y
6. [6]
  N.F. Bunkin, A.V. Shkirin, N.V. Penkov, et al., Front. Chem. 9(2021) 630074. doi: 10.3389/fchem.2021.630074
7. [7]
  E. Stride, T. Segers, G. Lajoinie, et al., Ultrasound Med. Bio. 46(2020) 1326–1343. doi: 10.1016/j.ultrasmedbio.2020.01.027
8. [8]
  M.S. Khan, J. Hwang, K. Lee, et al., Cancers 11(2019) 1464. doi: 10.3390/cancers11101464
9. [9]
  L.J. Delaney, J.R. Eisenbrey, D. Brown, et al., Acta Biomater. 130(2021) 385–394. doi: 10.1016/j.actbio.2021.05.046
10. [10]
  M. Zahiri, S. Taghavi, K. Abnous, et al., J. Control. Release 339(2021) 164–194. doi: 10.1016/j.jconrel.2021.09.032
11. [11]
  A.H. Liao, C.R. Hung, H.K. Chen, C.P. Chiang, Sci. Rep. 8(2018) 8327. doi: 10.1038/s41598-018-26702-z
12. [12]
  M. Lee, E.Y. Lee, D. Lee, B.J. Park, Soft Matter 11(2015) 2067–2079. doi: 10.1039/C5SM00113G
13. [13]
  F. Cavalieri, M. Ashokkumar, F. Grieser, F. Caruso, Langmuir 24(2008) 10078–10083. doi: 10.1021/la801093q
14. [14]
  M.R. Böhmer, R. Schroeders, J.A.M. Steenbakkers, et al., Colloid. Surface. A 289(2006) 96–104. doi: 10.1016/j.colsurfa.2006.04.011
15. [15]
  M. Motornov, Y. Roiter, I. Tokarev, S. Minko, Prog. Polym. Sci. 35(2010) 174–211. doi: 10.1016/j.progpolymsci.2009.10.004
16. [16]
  E. Castro-Hernández, W. van Hoeve, D. Lohse, J.M. Gordillo, Lab Chip 11(2011) 2023–2029. doi: 10.1039/c0lc00731e
17. [17]
  G. Wang, L. Song, X. Hou, et al., Biomaterials 236(2020) 119803. doi: 10.1016/j.biomaterials.2020.119803
18. [18]
  A.A. Exner, M.C. Kolios, Curr. Opin. Colloid In. 54(2021) 101463. doi: 10.1016/j.cocis.2021.101463
19. [19]
  P.S. Sheeran, N. Matsuura, M.A. Borden, et al., IEEE T. Ultrason. Ferr. 64(2017) 252–263. doi: 10.1109/TUFFC.2016.2619685
20. [20]
  Z. Hu, S.V. Bachawal, X. Li, et al., Mol. Imaging Biol. 24(2022) 333–340. doi: 10.1007/s11307-021-01680-3
21. [21]
  G. Köse, M. Darguzyte, F. Kiessling, Nanomaterials 10(2020) 1935. doi: 10.3390/nano10101935
22. [22]
  A.L. Klibanov, P.T. Rasche, M.S. Hughes, et al., Invest. Radiol. 39(2004) 187–195. doi: 10.1097/01.rli.0000115926.96796.75
23. [23]
  M.W. Keller, S.S. Segal, S. Kaul, B. Duling, Circ. Res. 65(1989) 458–467. doi: 10.1161/01.RES.65.2.458
24. [24]
  S.V. Bachawal, K.C. Jensen, A.M. Lutz, et al., Cancer Res. 73(2013) 1689–1698.
25. [25]
  L. Zhang, T. Yin, B. Li, et al., ACS Nano 12(2018) 3449–3460. doi: 10.1021/acsnano.8b00076
26. [26]
  D.G. Ramirez, E. Abenojar, C. Hernandez, et al., Nat. Commun. 11(2020) 2238. doi: 10.1038/s41467-020-15957-8
27. [27]
  J. Wu, Y. Long, M. Li, Q. He, Acta Pharm. Sin. B 11(2021) 2286–2305. doi: 10.1016/j.apsb.2020.11.024
28. [28]
  H. Maeda, Adv. Drug Deliver. Rev. 91(2015) 3–6. doi: 10.1016/j.addr.2015.01.002
29. [29]
  X. Huang, W. Liao, Z. Xie, et al., Mat. Sci. Eng. C: Mat. 90(2018) 27–37. doi: 10.1016/j.msec.2018.04.036
30. [30]
  J.M. Gorce, M. Arditi, M. Schneider, Invest. Radiol. 35(2000) 661–671. doi: 10.1097/00004424-200011000-00003
31. [31]
  P.S. Sheeran, V.P. Wong, S. Luois, et al., Ultrasound Med. Biol. 37(2011) 1518–1530. doi: 10.1016/j.ultrasmedbio.2011.05.021
32. [32]
  J. Xu, Y. Chen, L. Deng, et al., Biomaterials 106(2016) 264–275. doi: 10.1016/j.biomaterials.2016.08.034
33. [33]
  T.O. Matsunaga, P.S. Sheeran, S. Luois, et al., Theranostics 2(2012) 1185–1198. doi: 10.7150/thno.4846
34. [34]
  H. Yang, W. Cai, W. Lv, et al., Int. J. Nanomed. 14(2019) 7079–7093. doi: 10.2147/IJN.S207419
35. [35]
  X. Shu, Y. Chen, P. Yan, et al., J. Control. Release 347(2022) 270–281. doi: 10.1016/j.jconrel.2022.05.010
36. [36]
  H. Zhu, D. Qin, Y. Wu, et al., ACS Appl. Mater. Interfaces 10(2018) 29251–29259. doi: 10.1021/acsami.8b08190
37. [37]
  J. An, J. Zhang, F. Dong, et al., Small 18(2022) 2105989. doi: 10.1002/smll.202105989
38. [38]
  D.G. Ramirez, M. Ciccaglione, A.K. Upadhyay, et al., Proc. Natl. Acad. Sci. U. S. A. 118(2021) e2022523118. doi: 10.1073/pnas.2022523118
39. [39]
  N.Y. Rapoport, A.M. Kennedy, J.E. Shea, et al., J. Control. Release 138(2009) 268–276. doi: 10.1016/j.jconrel.2009.05.026
40. [40]
  S. Park, G. Son, Ultrason. Sonochem. 71(2021) 105361. doi: 10.1016/j.ultsonch.2020.105361
41. [41]
  P.S. Sheeran, S.H. Luois, L.B. Mullin, et al., Biomaterials 33(2012) 3262–3269. doi: 10.1016/j.biomaterials.2012.01.021
42. [42]
  P.S. Sheeran, J.D. Rojas, C. Puett, et al., Ultrasound Med. Biol. 41(2015) 814–831. doi: 10.1016/j.ultrasmedbio.2014.10.020
43. [43]
  D.S. Li, S. Schneewind, M. Bruce, et al., Nano Lett. 19(2019) 173–181. doi: 10.1021/acs.nanolett.8b03585
44. [44]
  R.W. Bourdeau, A. Lee-Gosselin, A. Lakshmanan, et al., Nature 553(2018) 86–90. doi: 10.1038/nature25021
45. [45]
  F. Pfeifer, Nat. Rev. Microbiol. 10(2012) 705–715. doi: 10.1038/nrmicro2834
46. [46]
  D.I. Piraner, A. Farhadi, H.C. Davis, et al., Biochemistry 56(2017) 5202–5209. doi: 10.1021/acs.biochem.7b00443
47. [47]
  M.G. Shapiro, P.W. Goodwill, A. Neogy, et al., Nat. Nanotechnol. 9(2014) 311–316. doi: 10.1038/nnano.2014.32
48. [48]
  J. Le Floc'h, A. Zlitni, H.A. Bilton, et al., Mol. Imaging Biol. 20(2018) 230–239. doi: 10.1007/s11307-017-1122-6
49. [49]
  J. Huang, H. Zhang, Y. Yu, et al., Biomaterials 35(2014) 550–566. doi: 10.1016/j.biomaterials.2013.09.089
50. [50]
  L.J. Cruz, P.J. Tacken, R. Fokkink, C.G. Figdor, Biomaterials 32(2011) 6791–6803. doi: 10.1016/j.biomaterials.2011.04.082
51. [51]
  Q. Feng, W. Zhang, X. Yang, et al., Adv. Healthc. Mater. 7(2018) 1700957. doi: 10.1002/adhm.201700957
52. [52]
  E. Kang, H.S. Min, J. Lee, et al., Angew. Chem. Int. Ed. 49(2010) 524–528. doi: 10.1002/anie.200903841
53. [53]
  M. Kim, J.H. Lee, S.E. Kim, et al., ACS Appl. Mater. Interfaces 8(2016) 8409–8418. doi: 10.1021/acsami.6b02115
54. [54]
  S. Chen, X.L. Xu, B. Zhou, et al., ACS Appl. Mater. Interfaces 11(2019) 22194–22205. doi: 10.1021/acsami.9b06745
55. [55]
  K.H. Min, H.S. Min, H.J. Lee, et al., ACS Nano 9(2015) 134–145. doi: 10.1021/nn506210a
56. [56]
  M. Versluis, E. Stride, G. Lajoinie, et al., Ultrasound Med. Biol. 46(2020) 2117–2144. doi: 10.1016/j.ultrasmedbio.2020.04.014
57. [57]
  Y. Yang, L. Jing, X. Li, et al., Theranostics 7(2017) 466–481. doi: 10.7150/thno.17411
58. [58]
  B. Helfield, Ultrasound Med. Biol. 45(2019) 282–300. doi: 10.1016/j.ultrasmedbio.2018.09.020
59. [59]
  Y. Wang, H. Cong, S. Wang, et al., J. Mater. Chem. B 9(2021) 7633–7661. doi: 10.1039/D1TB00850A
60. [60]
  M.W.N. Burns, R.F. Mattrey, J. Lux, ACS Appl. Mater. Interfaces 12(2020) 52298–52306. doi: 10.1021/acsami.0c12043
61. [61]
  H. Chen, Z. Zhen, T. Todd, et al., Mater. Sci. Eng. R. Rep. 74(2013) 35–69. doi: 10.1016/j.mser.2013.03.001
62. [62]
  A. Jafari Sojahrood, A.C. de Leon, R. Lee, et al., ACS Nano 15(2021) 4901–4915. doi: 10.1021/acsnano.0c09701
63. [63]
  H. Wu, N.G. Rognin, T.M. Krupka, et al., Ultrasound Med. Biol. 39(2013) 2137–2146. doi: 10.1016/j.ultrasmedbio.2013.05.007
64. [64]
  A. de Leon, R. Perera, C. Hernandez, et al., Nanoscale 11(2019) 15647–15658. doi: 10.1039/C9NR04828F
65. [65]
  R. Zhao, J. Jiang, H. Li, et al., J. Neuroinflamm. 15(2018) 334. doi: 10.1186/s12974-018-1368-1
66. [66]
  C. Wang, S. Yang, X. Chen, et al., Rev. Cardiovasc. Med. 22(2021) 1657–1666. doi: 10.31083/j.rcm2204173
67. [67]
  Y.I. Yoon, S.W. Ha, H.J. Lee, J. Magn. Reson. Imaging 48(2018) 1610–1616. doi: 10.1002/jmri.26217
68. [68]
  X. Mi, X. Guo, H. Du, et al., Nanomedicine 42(2022) 102533. doi: 10.1016/j.nano.2022.102533
69. [69]
  Y. Xie, Y. Chen, L. Zhang, et al., Transplantation 103.8(2019) 1603.
70. [70]
  L. Xinlong, Z. Xin, L. Chong, Chin. Chem. Lett. 32(2021) 2347–2358. doi: 10.1016/j.cclet.2021.03.015
71. [71]
  M. Zhang, S. Gao, D. Yang, et al., Acta Pharm. Sin. B 11(2021) 2265–2285. doi: 10.1016/j.apsb.2021.03.033
72. [72]
  J. Yang, X. Miao, Y. Guan, et al., Adv. Healthc. Mater. 10(2021) 2101628. doi: 10.1002/adhm.202101628
73. [73]
  L. Xu, Y. Chen, Q. Jin, et al., Mol. Pharmaceut. 18(2021) 2974–2985. doi: 10.1021/acs.molpharmaceut.1c00145
74. [74]
  N. Jugniot, T.F. Massoud, J.J. Dahl, R. Paulmurugan, J. Nanobiotechnol. 20(2022) 267. doi: 10.1186/s12951-022-01484-9
75. [75]
  C.K. Kuhl, Annu. Rev. Med. 70(2019) 501–519. doi: 10.1146/annurev-med-121417-100403
76. [76]
  M.M. Siddiqui, S. Rais-Bahrami, B. Turkbey, et al., JAMA 313(2015) 390–397. doi: 10.1001/jama.2014.17942
77. [77]
  D. Fu, X. Huang, Z. Lv, et al., Bioengineered 13(2022) 7104–7116. doi: 10.1080/21655979.2022.2045832
78. [78]
  J. Deprez, G. Lajoinie, Y. Engelen, et al., Adv. Drug Deliv. Rev. 172(2021) 9–36. doi: 10.1016/j.addr.2021.02.015
79. [79]
  S. Snipstad, K. Vikedal, M. Maardalen, et al., Adv. Drug Deliv. Rev. 177(2021) 113847. doi: 10.1016/j.addr.2021.113847
80. [80]
  S.P. Wrenn, S.M. Dicker, E.F. Small, et al., Theranostics 2(2012) 1140–1159. doi: 10.7150/thno.4305
81. [81]
  Z. Izadifar, P. Babyn, D. Chapman, J. Med. Biol. Eng. 39(2019) 259–276. doi: 10.1007/s40846-018-0391-0
82. [82]
  Thomas Leong, Ashok kumar, et al., Acoust. Aust. 39.2(2011) 54–63.
83. [83]
  C.C. Church, E.L. Carstensen, Ultrasound Med. Biol. 27(2001) 1435–1437. doi: 10.1016/S0301-5629(01)00441-0
84. [84]
  Y.J. Ho, H.C. Chang, C.W. Lin, et al., J. Control. Release 333(2021) 316–327. doi: 10.1016/j.jconrel.2021.03.044
85. [85]
  J. Tu, A.C.H. Yu, BME Front. 2022(2022) 9807347.
86. [86]
  S. El Kadi, T.R. Porter, N.J.W. Verouden, et al., JACC-Cardiovasc. Imag. 15(2022) 345–360.
87. [87]
  K.H. Song, B.K. Harvey, M.A. Borden, Theranostics 8(2018) 4393–4408. doi: 10.7150/thno.26869
88. [88]
  Q. Liu, J. Jiang, L. Tang, M. Chen, Ann. Transl. Med. 8(2020) 298. doi: 10.21037/atm.2020.02.155
89. [89]
  N. Qu, D. Shi, M. Shang, et al., Med. Sci. Monit. 24(2018) 9054–9062. doi: 10.12659/MSM.910790
90. [90]
  S. Kotopoulis, M. Popa, M. Mayoral Safont, et al., Pharmaceutics 14(2022) 98. doi: 10.3390/pharmaceutics14010098
91. [91]
  J. Wischhusen, F. Padilla, IRBM 40(2019) 10–15. doi: 10.1016/j.irbm.2018.11.005
92. [92]
  M. Argenziano, S. Occhipinti, A. Scomparin, et al., Drug Deliv. Transl. Res. 12(2022) 2007–2018. doi: 10.1007/s13346-022-01185-8
93. [93]
  L. Hui, X. Xi, H. Jianbo, et al., Chin. Chem. Lett. 32(2021) 1759–1764. doi: 10.1016/j.cclet.2020.12.004
94. [94]
  G. Dimcevski, S. Kotopoulis, T. Bjånes, et al., J. Control. Release 243(2016) 172–181. doi: 10.1016/j.jconrel.2016.10.007
95. [95]
  J.R. Eisenbrey, F. Forsberg, C.E. Wessner, et al., Radiology 298(2021) 450–457. doi: 10.1148/radiol.2020202321
96. [96]
  L. Sun, J.E. Zhou, T. Luo, et al., Adv. Mater. 34(2022) e2109969. doi: 10.1002/adma.202109969
97. [97]
  T. Liao, Q. Li, Y. Zhang, et al., J. Heart Lung Transpl. 39(2020) 481–490. doi: 10.1016/j.healun.2020.02.002
98. [98]
  J. Zhong, Y. Sun, Y. Han, et al., J. Thromb. Haemost. 19(2021) 738–752. doi: 10.1111/jth.15110
99. [99]
  K. Fan, L. Zeng, J. Guo, et al., Theranostics 11(2021) 2670–2690. doi: 10.7150/thno.53083
100. [100]
  X. Mi, H. Du, X. Guo, et al., Acta Biomater. 141(2022) 388–397. doi: 10.1016/j.actbio.2022.01.023
101. [101]
  X. Wang, M. Shang, X. Sun, et al., J. Control. Release 343(2022) 66–77. doi: 10.1016/j.jconrel.2022.01.009
102. [102]
  Z. Liu, H. Wang, Q. Zhao, et al., Mater. Express 11(2021) 240–247. doi: 10.1364/OME.412006
103. [103]
  G. Wei, Y. Wang, G. Yang, et al., Theranostics 11(2021) 6370–6392. doi: 10.7150/thno.57828
104. [104]
  N. Ingram, L.E. McVeigh, R.H. Abou-Saleh, et al., Theranostics 10(2020) 10973–10992. doi: 10.7150/thno.49670
105. [105]
  X. Yang, M. Zhao, Z. Wu, et al., ACS Nano 16(2022) 3417–3431. doi: 10.1021/acsnano.2c00462
106. [106]
  N. Yumita, R. Nishigaki, K. Umemura, S. Umemura, Jpn. J. Cancer Res. 80(1989) 219–222. doi: 10.1111/j.1349-7006.1989.tb02295.x
107. [107]
  Z. Jiayi, O. Ai, S. Zhuanglin, et al., Chin. Chem. Lett. 33(2022) 1907–1912. doi: 10.1016/j.cclet.2021.11.017
108. [108]
  W. Wu, Y. Pu, H. Lin, et al., Research 2021(2021) 9769867.
109. [109]
  K. Logan, F. Foglietta, H. Nesbitt, et al., Eur. J. Pharm. Biopharm. 139(2019) 224–231. doi: 10.1016/j.ejpb.2019.04.003
110. [110]
  W. Cao, Y. Liu, P. Ran, et al., ACS Appl. Mater. Interfaces 13(2021) 58411–58421. doi: 10.1021/acsami.1c19288
111. [111]
  X. Jintao, Z. Nanqian, Y. Yuping, et al., Colloids Surf. B: Biointerfaces 190(2020) 110887. doi: 10.1016/j.colsurfb.2020.110887
112. [112]
  R.J. Browning, S. Able, J.L. Ruan, et al., J. Control. Release 337(2021) 371–377. doi: 10.1016/j.jconrel.2021.07.020
113. [113]
  G. Sun, J. Zhang, S. Wu, Y. Liu, Mater. Express 11(2021) 1045–1050. doi: 10.1166/mex.2021.2029
114. [114]
  X.M. Anguela, K.A. High, Annu. Rev. Med. 70(2019) 273–288. doi: 10.1146/annurev-med-012017-043332
115. [115]
  Y. Zhou, M. Yu, C. Tie, et al., Research 2021(2021) 9760398.
116. [116]
  A.P.G. Walsh, H.N. Gordon, K. Peter, X. Wang, Adv. Drug Deliv. Rev. 179(2021) 113998. doi: 10.1016/j.addr.2021.113998
117. [117]
  M. Wu, H. Xiong, H. Zou, et al., Acta Biomater 70(2018) 211–226. doi: 10.1016/j.actbio.2018.02.006
118. [118]
  J.C. Wischhusen, S.M. Chowdhury, T. Lee, et al., J. Control. Release 321(2020) 272–284. doi: 10.1016/j.jconrel.2020.01.051
119. [119]
  F. Wang, T. Shi, C. Su, Ultrasound Med. Biol. 45(2019) 859–866. doi: 10.1016/j.ultrasmedbio.2018.10.021
120. [120]
  E. Jung, C. Kang, J. Lee, et al., ACS Nano 12(2018) 392–401. doi: 10.1021/acsnano.7b06560
121. [121]
  L. Zhang, H. Yi, J. Song, et al., ACS Appl. Mater. Interfaces 11(2019) 9355–9366. doi: 10.1021/acsami.8b21968
122. [122]
  A. Farhadi, G.H. Ho, D.P. Sawyer, et al., Science 365(2019) 1469–1475. doi: 10.1126/science.aax4804
123. [123]
  A. Bar-Zion, A. Nourmahnad, D.R. Mittelstein, et al., Nat. Nanotechnol. 16(2021) 1403–1412. doi: 10.1038/s41565-021-00971-8
124. [124]
  Y. Zhou, X. Han, X. Jing, Y. Chen, Adv. Healthc. Mater. 6(2017) 1700646. doi: 10.1002/adhm.201700646
125. [125]
  C. Zhang, J. Liu, H. Guo, et al., Adv. Healthc. Mater. 8(2019) 1900409. doi: 10.1002/adhm.201900409
126. [126]
  L. Chen, S.F. Zhou, L. Su, J. Song, ACS Nano 13(2019) 10887–10917. doi: 10.1021/acsnano.9b04954
127. [127]
  Y. Luodan, C. Yu, C. Hangrong, Chin. Chem. Lett. 28(2017) 1841–1850. doi: 10.1016/j.cclet.2017.05.023
128. [128]
  C. Bogdan, Nat. Immunol. 2(2001) 907–916. doi: 10.1038/ni1001-907
129. [129]
  L. Van Hese, L. Al Tmimi, S. Devroe, et al., Brit. J. Anaesth. 121(2018) 1365–1368. doi: 10.1016/j.bja.2018.08.014
130. [130]
  J. Jin, M. Li, J. Li, et al., ACS Appl. Mater. Interfaces 13(2021) 43880–43891. doi: 10.1021/acsami.1c06014
1. [1]
  Yuqing Zhu , Haohao Chen , Li Wang , Liqun Ye , Houle Zhou , Qintian Peng , Huaiyong Zhu , Yingping Huang . Piezoelectric materials for pollutants degradation: State-of-the-art accomplishments and prospects. Chinese Chemical Letters, 2024, 35(4): 108884-. doi: 10.1016/j.cclet.2023.108884
2. [2]
  Junjie Wang , Yan Wang , Zhengdong Li , Changqiang Xie , Musammir Khan , Xingzhou Peng , Fabiao Yu . Triphenylamine-AIEgens photoactive materials for cancer theranostics. Chinese Chemical Letters, 2024, 35(6): 108934-. doi: 10.1016/j.cclet.2023.108934
3. [3]
  Manoj Kumar Sarangi , L․D Patel , Goutam Rath , Sitansu Sekhar Nanda , Dong Kee Yi . Metal organic framework modulated nanozymes tailored with their biomedical approaches. Chinese Chemical Letters, 2024, 35(11): 109381-. doi: 10.1016/j.cclet.2023.109381
4. [4]
  Jia-Qi Feng , Xiang Tian , Rui-Ge Cao , Yong-Xiu Li , Wen-Long Liu , Rong Huang , Si-Yong Qin , Ai-Qing Zhang , Yin-Jia Cheng . An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy: Real-time tumor-tracking and chemical-enhanced photodynamic therapy. Chinese Chemical Letters, 2024, 35(12): 109657-. doi: 10.1016/j.cclet.2024.109657
5. [5]
  Haijing Cui , Weihao Zhu , Chuning Yue , Ming Yang , Wenzhi Ren , Aiguo Wu . Recent progress of ultrasound-responsive titanium dioxide sonosensitizers in cancer treatment. Chinese Chemical Letters, 2024, 35(10): 109727-. doi: 10.1016/j.cclet.2024.109727
6. [6]
  Hui Liu , Xi Xiang , Jian-Bo Huang , Bi-Hui Zhu , Li-Yun Wang , Yuan-Jiao Tang , Fang-Xue Du , Ling Li , Feng Yan , Lang Ma , Li Qiu . Corrigendum to "Ultrasound augmenting injectable chemotaxis hydrogel for articular cartilage repair in osteoarthritis" [Chinese Chemical Letters 32 (2021) 1759-1764]. Chinese Chemical Letters, 2025, 36(2): 110562-. doi: 10.1016/j.cclet.2024.110562
7. [7]
  Yiqiao Chen , Ao Liu , Biwen Yang , Zhenzhen Li , Binggang Ye , Zhouyi Guo , Zhiming Liu , Haolin Chen . Photoluminescence and photothermal conversion in boric acid derived carbon dots for targeted microbial theranostics. Chinese Chemical Letters, 2024, 35(9): 109295-. doi: 10.1016/j.cclet.2023.109295
8. [8]
  Yunlong Li , Xinyu Zhang , Shuang Liu , Chunsheng Li , Qiang Wang , Jin Ye , Yong Lu , Jiating Xu . Engineered iron-based metal-organic frameworks nanoplatforms for cancer theranostics: A mini review. Chinese Chemical Letters, 2025, 36(2): 110501-. doi: 10.1016/j.cclet.2024.110501
9. [9]
  Xiao-Fang Lv , Xiao-Yun Ran , Yu Zhao , Rui-Rui Zhang , Li-Na Zhang , Jing Shi , Ji-Xuan Xu , Qing-Quan Kong , Xiao-Qi Yu , Kun Li . Combing NIR-Ⅱ molecular dye with magnetic nanoparticles for enhanced photothermal theranostics with a 95.6% photothermal conversion efficiency. Chinese Chemical Letters, 2025, 36(4): 110027-. doi: 10.1016/j.cclet.2024.110027

Get Citation

PDF

XML

Metrics

PDF Downloads(4)
Abstract views(415)
HTML views(13)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142