Citation: Peiyu Wang, Huirong Lin, Changhong Li, Gang Liu. ICG/Lecithin: A promising theranostic agent for simultaneous therapy and diagnosis of MRI and PAI[J]. Chinese Chemical Letters, ;2023, 34(7): 108068. doi: 10.1016/j.cclet.2022.108068 shu

ICG/Lecithin: A promising theranostic agent for simultaneous therapy and diagnosis of MRI and PAI

Peiyu Wang ^a ,
Huirong Lin ^a ,
Changhong Li ^{a, b} ,
Gang Liu ^{a, b, *,}

a.
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China
b.
State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen 361102, China

gangliu.cmitm@xmu.edu.cn

Received Date: 2 July 2022
Revised Date: 21 November 2022
Accepted Date: 12 December 2022
Available Online: 13 December 2022

Figures(2)

A chronic liver disease usually results in iron accumulation, and an excess of iron will further aggravate liver injury, forming a vicious circle. Likewise, it also plays a significant role in other organs when it comes to iron metabolism. A long time passes between the time it takes to break through to MRI-based iron diagnosis and its ability to distinguish the types of iron accumulation accurately and quickly. This work highlighted a new type of iron accumulation treatment solution integrated with diagnosis and treatment. A chelating method for ICG and Leci that can assist PAI and MRI to achieve better diagnostic and therapeutic effects. This work revealed biomaterial engineering techniques are being adapted to address clinical medical problems through cutting-edge research.
- Iron overloaded diseases,
- Magnetic resonance imaging,
- Photoacoustic imaging,
- Supramolecular assembly,
- Theranostic agent
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沈阳化工大学材料科学与工程学院沈阳 110142