Citation: Peihui Shan, Ruilian Lin, Ming Liu, Zhu Tao, Xin Xiao, Jingxin Liu. Recognition of glycine by cucurbit[5]uril and cucurbit[6]uril: A comparative study of exo- and endo-binding[J]. Chinese Chemical Letters, ;2021, 32(7): 2301-2304. doi: 10.1016/j.cclet.2021.02.020 shu

Recognition of glycine by cucurbit[5]uril and cucurbit[6]uril: A comparative study of exo- and endo-binding

Peihui Shan ^a ,
Ruilian Lin ^b ,
Ming Liu ^a ,
Zhu Tao ^a ,
Xin Xiao ^{a, *,} ,
Jingxin Liu ^{b, *,}

a.
Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, China
b.
College of Chemistry and Chemical Engineering, Anhui University of Technology, Maanshan 243002, China

gyhxxiaoxin@163.com

jxliu411@ahut.edu.cn

Received Date: 11 November 2020
Revised Date: 3 February 2021
Accepted Date: 9 February 2021
Available Online: 12 February 2021

Figures(7)

Recognition features of glycine (Gly) with cucurbit[5]uril (Q[5]) and cucurbit[6]uril (Q[6]) both in aqueous solution and solid state were investigated by ¹H NMR spectroscopy and X-ray crystallography. ¹H NMR data indicate that the Gly is located outside of the portals of the Q[5], exhibiting exo binding with the Q[5]. In the case of the Q[6], the Gly shows endo binding or a dual binding mode (endo and exo binding) with the host, which depends on the amount of the host in the aqueous solution. X-ray crystallography clearly display that the Gly forms 2:1 exclusion complex with the Q[5], and 2:1 inclusion complex with the Q[6]. Interestingly, hydrogen bondings between the encapsulated Gly molecules in the Q[6] were observed.
- Cucurbituril,
- endo-binding,
- exo-binding,
- Selective recognition,
- Supramolecular assembly
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