Citation: Xie Jingli, Zhao Dongyuan. Continuous-flow photochemistry: An expanding horizon of sustainable technology[J]. Chinese Chemical Letters, ;2020, 31(9): 2395-2400. doi: 10.1016/j.cclet.2020.03.022 shu

Continuous-flow photochemistry: An expanding horizon of sustainable technology

Xie Jingli ^a,b,c,d,*, ,
Zhao Dongyuan ^e

a.
College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China
b.
Chemistry and Chemical Engineering Guangdong Laboratory, Guangdong Technion-Israel Institute of Technology (GTIIT), Shantou 515031, China
c.
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China
d.
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, China
e.
Department of Chemistry and Laboratory of Advanced Materials, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, iChEM and State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, China

Author Bio: Jingli Xie completed his BSc (1995), MSc degree (1998) at Jilin University and studied at Nanjing University with Prof. Qingjin Meng for his PhD (awarded in 2003). He was a postdoctoral researcher with Prof. Pingyun Feng at the University of California, Riverside (2003-2004) and with Prof. Anthony G. Wedd at the University of Melbourne (2005-2006). He took an Australian Postdoctoral Fellowship (2007-2009, with Prof. Wedd), Monash Research Fellowship (2010-2015, relinquished in 2012), Marie Curie International Incoming Fellowship at the University of Glasgow (2011-2013, with Prof. Leroy Cronin), consecutively. Currently his research focuses on flow chemistry, polyoxometalates and supramolecular science. In his spare time, Jingli enjoys running half-marathon in the XiuHu (ShowLake) Park and watching NBA games (http://xielab.zjxu.edu.cn)
Dongyuan Zhao is Hao-Qing Chair Professor at Fudan University and the Academician of Chinese Academy of Sciences. The research goal of his group is the design, synthesis and characterization of new materials. Now he serves at the editorial board of several journals including ACS Central Science, Joule and National Science Review (http://www.mesogroup.fudan.edu.cn)

jlxie@mail.zjxu.edu.cn

Received Date: 15 January 2020
Revised Date: 28 February 2020
Accepted Date: 7 March 2020
Available Online: 9 March 2020

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Understanding the unique characteristics of continuous-flow photochemistry will lead to a paradigm shift in the way we enhance sustainability and wellbeing. In this mini-review, we first provide a succinct overview of working principles of this technique and discuss several recent synthetic protocols. Then, emphasis is given to those representative examples which address environmental issues such as indoor air pollutants and water contamination. Finally, recent progress made using this technique to deal with rising CO₂ emission, solar energy utilization and biomedical equipment is described. It is believed that this mini-review could inspire more chemists to utilize this technique in their research, either in the academic or industrial field.
- Continuous-flow photochemistry,
- Synthesis,
- Environmental application,
- Micro-reaction technology,
- Sustainable technology
1. [1]
  A. Adamo, R.L. Beingessner, M. Behnam, et al., Science 352 (2016) 61-67. doi: 10.1126/science.aaf1337
2. [2]
  J. Zhang, C. Gong, X. Zeng, et al., Coord. Chem. Rev. 324 (2016) 39-53. doi: 10.1016/j.ccr.2016.06.011
3. [3]
  D. Cambié, C. Bottecchia, N.J.W. Straathof, V. Hessel, T. Noël, Chem. Rev. 116 (2016) 10276-10341. doi: 10.1021/acs.chemrev.5b00707
4. [4]
  T. Noël, J. Flow Chem. 7 (2017) 87-93. doi: 10.1556/1846.2017.00022
5. [5]
  M. Oelgemöller, T. Goodine, P. Malakar, Flow photochemistry-a green technology with a bright future, in: L. Vaccaro (Ed.), Sustainable Flow Chemistry: Methods and Applications, Wiley-VCH, Weinheim, 2017, pp. 1-24.
6. [6]
  M. Oelgemöller, Chem. Eng. Technol. 35 (2012) 1144-1152. doi: 10.1002/ceat.201200009
7. [7]
  M. Oelgemöller, O. Shvydkiv, Molecules 16 (2011) 7522-7550. doi: 10.3390/molecules16097522
8. [8]
  F. Lévesque, P.H. Seeberger, Angew. Chem. Int. Ed. 51 (2012) 1706-1709. doi: 10.1002/anie.201107446
9. [9]
  K. Loubière, M. Oelgemöller, T. Aillet, et al., Chem. Eng. Process.104 (2016) 120-132. doi: 10.1016/j.cep.2016.02.008
10. [10]
  D. Staveness, T.M. Sodano, K. Li, et al., Chemistry 5 (2019) 215-226. doi: 10.1016/j.chempr.2018.10.017
11. [11]
  R.C. McAtee, E.J. McClain, C.R.J. Stephenson, Trends Analyt. Chem.1 (2019) 111-125. doi: 10.1016/j.trechm.2019.01.008
12. [12]
  C. Alonso, E.M. de Marigorta, G. Rubiales, et al., Chem. Rev. 115 (2015) 1847-1935. doi: 10.1021/cr500368h
13. [13]
  J.W. Beatty, J.J. Douglas, K.P. Cole, et al., Nat. Commun. 6 (2015) 1-6.
14. [14]
  K.C. Harper, E.G. Moschetta, S.V. Bordawekar, et al., ACS Cent. Sci. 5 (2019) 109-115. doi: 10.1021/acscentsci.8b00728
15. [15]
  N. Emmanuel, C. Mendoza, M. Winter, et al., Org. Process Res. Dev. 21 (2017) 1435-1438. doi: 10.1021/acs.oprd.7b00212
16. [16]
  I. Abdiaj, C.R. Horn, J. Alcazar, J. Org. Chem. 84 (2019) 4748-4753. doi: 10.1021/acs.joc.8b02358
17. [17]
  M. Sayes, G. Benoit, A.B. Charette, Angew. Chem. Int. Ed. 57 (2018) 13514-13518. doi: 10.1002/anie.201807347
18. [18]
  M. Hunger, G. Hüsken, H.J.H. Brouwers, Concrete Res. 40 (2010) 313-320. doi: 10.1016/j.cemconres.2009.09.013
19. [19]
  J. Mo, Y. Zhang, Q. Xu, et al., Atmos. Environ. 43 (2009) 2229-2246. doi: 10.1016/j.atmosenv.2009.01.034
20. [20]
  S. Wang, H.M. Ang, M.O. Tade, Environ. Int. 33 (2007) 694-705. doi: 10.1016/j.envint.2007.02.011
21. [21]
  J. Mo, Y. Zhang, R. Yang, et al., Build. Environ. 43 (2008) 238-245. doi: 10.1016/j.buildenv.2005.12.027
22. [22]
  Q.L. Yu, H.J.H. Brouwers, Appl. Catal. B -Environ. 92 (2009) 454-461. doi: 10.1016/j.apcatb.2009.09.004
23. [23]
  L. Yang, Z. Liu, J. Shi, et al., Catal. Today 126 (2007) 359-368. doi: 10.1016/j.cattod.2007.06.017
24. [24]
  F.B. Li, X.Z. Li, C.H. Ao, et al., Chemosphere 59 (2005) 787-800. doi: 10.1016/j.chemosphere.2004.11.019
25. [25]
  N. Wang, X. Zhang, Y. Wang, et al., Lab Chip. 14 (2014) 1074-1082. doi: 10.1039/C3LC51233A
26. [26]
  S. Malato, P. Fernández-Ibánez, M.I. Maldonado, et al., Catal. Today 147 (2009) 1-59. doi: 10.1016/j.cattod.2009.06.018
27. [27]
  L. Lei, N. Wang, X.M. Zhang, et al., Biomicrofluidics 4 (2010) 043004. doi: 10.1063/1.3491471
28. [28]
  M. Rahimi, B. Aghel, M. Sadeghi, et al., Water Treat. 52 (2014) 5513-5519. doi: 10.1080/19443994.2013.807471
29. [29]
  S.P. Albu, A. Ghicov, J.M. Macak, et al., Nano Lett. 7 (2007) 1286-1289. doi: 10.1021/nl070264k
30. [30]
  L. Wang, A. Mazare, I. Hwang, et al., Chem. Commun. 53 (2017) 11763-11766. doi: 10.1039/C7CC06889A
31. [31]
  H. Seo, M.H. Katcher, T.F. Jamison, Nat. Chem. 9 (2017) 453-456. doi: 10.1038/nchem.2690
32. [32]
  H. Seo, A. Liu, T.F. Jamison, J. Am. Chem. Soc. 139 (2017) 13969-13972. doi: 10.1021/jacs.7b05942
33. [33]
  D. Cambié, F. Zhao, V. Hessel, et al., Angew. Chem. Int. Ed. 56 (2017) 1050-1054. doi: 10.1002/anie.201611101
34. [34]
  J.A. Lv, Y. Liu, J. Wei, et al., Nature 537 (2016) 179-184. doi: 10.1038/nature19344
35. [35]
  N.K. Shrestha, J.M. Macak, F. Schmidt-Stein, et al., Angew. Chem. Int. Ed. 48 (2009) 969-972. doi: 10.1002/anie.200804429
36. [36]
  D. Cambié, J. Dobbelaar, P. Riente, et al., Angew. Chem. Int. Ed. 58 (2019) 14374-14378. doi: 10.1002/anie.201908553
37. [37]
  L. Buzzetti, G.E.M. Crisenza, P. Melchiorre, Angew. Chem. Int. Ed. 58 (2019) 3730-3747. doi: 10.1002/anie.201809984
38. [38]
  C.P. Haas, T. Roider, R.W. Hoffmann, et al., React. Chem. Eng. 4 (2019) 1912-1916. doi: 10.1039/C9RE00339H
39. [39]
  S. Fuse, N. Tanabe, M. Yoshida, et al., Chem. Commun. 46 (2010) 8722-8724. doi: 10.1039/c0cc02239j
40. [40]
  J. Turconi, F. Griolet, R. Guevel, et al., Org. Process Res. Dev. 18 (2014) 417-422. doi: 10.1021/op4003196
41. [41]
  J. Turconi, F. Griolet, R. Guevel, et al., Org. Process Res. Dev. 18 (2014) 831. doi: 10.1021/op5001397
42. [42]
  J.H. Clark, Green Chem. 1 (1999) 1-8. doi: 10.1039/a807961g
43. [43]
  A. Gavriilidis, A. Constantinou, K. Hellgardt, et al., React. Chem. Eng. 1 (2016) 595-612. doi: 10.1039/C6RE00155F
44. [44]
  C.W. Coley, D.A. Thomas Ⅲ, J.A.M. Lummiss, et al., Science 365 (2019) eaax1566. doi: 10.1126/science.aax1566
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