Citation: Ye Wei, Wang Lingren, Zhao Jie, Fang Quentin Q., Ming Weihua. Recyclable, non-leaching antimicrobial magnetic nanoparticles[J]. Chinese Chemical Letters, ;2019, 30(12): 2047-2050. doi: 10.1016/j.cclet.2019.06.010 shu

Recyclable, non-leaching antimicrobial magnetic nanoparticles

Ye Wei ^a,b ,
Wang Lingren ^a,b ,
Zhao Jie ^a,c ,
Fang Quentin Q. ^d ,
Ming Weihua ^a,*,

a.
Department of Chemistry and Biochemistry, Georgia Southern University, Statesboro, GA 30460, United States
b.
Department of Mechanical and Materials Engineering, Huaiyin Institute of Technology, Huaian 223001, China
c.
Key Laboratory of Bionic Engineering, Ministry of Education, Jilin University, Changchun 130022, China
d.
Department of Biology, Georgia Southern University, Statesboro, GA 30460, United States

wming@georgiasouthern.edu

Received Date: 11 May 2019
Revised Date: 3 June 2019
Accepted Date: 5 June 2019
Available Online: 6 December 2019

Figures(7)

Pathogenic bacterial contaminations in water cause serious or even lethal threats. Strategies that effectively kill bacteria without causing environmental contamination are urgently needed in a wide range of applications. We prepared recyclable antimicrobial magnetic nanoparticles, Fe₃O₄@P(St-co-AcQAC), through surfactant-free seeded emulsion polymerization involving a polymerizable, hydrophobic quaternary ammonium compound (QAC). Fe₃O₄ particles were first synthesized by a solvothermal reaction, followed by functionalization with a methacrylic silane (MPS), and then copolymerized with a QAC-containing acrylic monomer (AcQAC), leading to Fe₃O₄@P(St-co-AcQAC) nanoparticles. As confirmed by antibacterial assays, these Fe₃O₄@P(St-co-AcQAC) nanoparticles exhibited strong antimicrobial action against both Gram-positive Staphylococcus epidermidis and Gram-negative Escherichia coli, without leaching out any bactericidal agent. An additional benefit of antimicrobial magnetic particles is that they can be easily recycled while maintaining excellent antimicrobial efficacy.
- Antimicrobial,
- Quaternary ammonium compound (QAC),
- Contact killing,
- Magnetic particles,
- Recyclability
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