Citation: Chen Qi, Lu Kuo, Zheng Chang, Xu Xiao-Fang, Lin Jing, Chen Wei-Min. A facile synthesis of cajaninstilbene acid and its derivatives[J]. Chinese Chemical Letters, ;2019, 30(8): 1527-1529. doi: 10.1016/j.cclet.2019.04.043 shu

A facile synthesis of cajaninstilbene acid and its derivatives

College of Pharmacy, Jinan University, Guangzhou 510632, China

linjing-jnu@163.com

twmchen@jnu.edu.cn

Received Date: 28 January 2019
Revised Date: 26 March 2019
Accepted Date: 11 April 2019
Available Online: 17 August 2019

Figures(3)

A four-step synthesis of methyl 6-formyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate (11) that can be used as building block for a facile synthesis of cajaninstilbene acid and its derivatives is reported. The synthesis of cajaninstilbene acid was accomplished in six steps with an overall yield of 20% starting from commercial materials by a synthesis whose key steps are TiCl₄-mediated [3 + 3] cyclization and McMurry coupling.
- Cajaninstilbene acid,
- Synthesis,
- Building block,
- Derivatives
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沈阳化工大学材料科学与工程学院沈阳 110142