Citation: Yang Jianlin, Zhang Ming, Wang Peng, Liu Wenjuan, Ruwei Shen. 2-Amino homopropargyl alcohols from the highly regioselective Ag₂CO₃-catalyzed nucleophilic openings of alkynyl epoxides by amines[J]. Chinese Chemical Letters, ;2018, 29(3): 524-526. doi: 10.1016/j.cclet.2017.09.001 shu

2-Amino homopropargyl alcohols from the highly regioselective Ag₂CO₃-catalyzed nucleophilic openings of alkynyl epoxides by amines

a.
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, China
b.
College of Materials Science and Engineering, Nanjing Tech University, Nanjing 210009, China

Corresponding author: Ruwei Shen, shenrw@njtech.edu.cn; srw1100@hotmail.com
Received Date: 4 July 2017
Revised Date: 26 August 2017
Accepted Date: 1 September 2017
Available Online: 6 March 2017

Figures(4)

The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented. The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields.
- Alkynyl epoxide,
- Ring opening,
- Silver catalysis,
- Regioselectivity,
- Amino alcohol
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沈阳化工大学材料科学与工程学院沈阳 110142

2-Amino homopropargyl alcohols from the highly regioselective Ag2CO3-catalyzed nucleophilic openings of alkynyl epoxides by amines

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通讯作者: 陈斌, bchen63@163.com

2-Amino homopropargyl alcohols from the highly regioselective Ag₂CO₃-catalyzed nucleophilic openings of alkynyl epoxides by amines